Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin-Dependent NAD+ Regeneration [0.03%]
核黄素补救通过依赖辅酶的NAD+再生支持伯氏疏螺旋体的糖酵解反应
Anna M Schulz,Grace E Easterling,Aaditya Balasubramaniyan et al.
Anna M Schulz et al.
Borrelia burgdorferi (Bb), the etiological agent of Lyme disease, lacks the genes for de novo riboflavin biosynthesis and depends on host-derived riboflavin to generate flavin cofactors FMN and FAD. Riboflavin salvage by Bb has demonstrated...
Distinct Spatial Organisation of Rho and RNA Polymerase in Salmonella Cells [0.03%]
宋内志贺氏菌细胞中Rho和RNA聚合酶具有不同的空间结构组织
Lionello Bossi,Romain Le Bars,Johnathan C Black et al.
Lionello Bossi et al.
Rho is a conserved, ATP-dependent RNA translocase that terminates transcription at hundreds of sites across bacterial genomes. Although the molecular mechanism of Rho-dependent termination is well characterized, its spatial interplay with R...
A Single-Nucleotide Substitution Generates a de Novo Promoter That Activates a Latent Metabolic Bypass in Escherichia coli [0.03%]
单核苷酸替代生成了一个新的启动子激活了大肠杆菌中的一个潜在的代谢旁路
Qiaoqiao Guo,Qi Zou,Jilong Qin et al.
Qiaoqiao Guo et al.
The Escherichia coli fabH gene encodes the 3-ketoacyl-ACP synthase III that initiates fatty acid synthesis. Deletion of the fabH gene results in severely limited fatty acid synthesis and tiny cells that are unusually sensitive to antibiotic...
A Phosphorylation-Dependent Partner-Switching-Like Module Regulates a Glycosyltransferase Required for Heterocyst Polysaccharide Layer Formation in Anabaena sp. Strain PCC 7120 [0.03%]
一个磷酸化依赖的类似蛋白质互换模块通过调节糖基转移酶控制鱼腥藻孢囊多糖层的形成
Mai Harada,Satoshi Matsuoka,Shigeki Ehira
Mai Harada
Heterocyst-specific polysaccharide (Hep) is an essential component of the heterocyst envelope in the filamentous cyanobacterium Anabaena sp. PCC 7120; however, the regulatory mechanisms that control Hep layer formation remain poorly underst...
Chain-Length Regulation by WzzE Is Necessary for, but Genetically Separable From, Cyclic Enterobacterial Common Antigen Synthesis [0.03%]
WzzE调节链长对环状肠杆菌共同抗原合成是必需的，但可以遗传分离
Joseph F Carr,Yohannes H Rezenom,Jennifer S Rudolf et al.
Joseph F Carr et al.
Enterobacterial common antigen (ECA) is a conserved glycan that supports intrinsic antibiotic resistance in Enterobacterales. ECA exists in outer membrane diacylglycerol-phosphate- and lipopolysaccharide-linked forms, and a cyclic periplasm...
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility [0.03%]
迁移还是不迁移：细菌何时以及如何抑制鞭毛运动
Fatemeh Mohagegh,Jacob Scadden,Matthew A B Baker
Fatemeh Mohagegh
Bacterial motility enables cells to migrate toward favourable environments and initiate surface colonisation. While motility can be lost through passive processes, such as shearing of filament, it frequently occurs as a tightly regulated re...
Roles of PknB and CslA in Cell Wall Morphogenesis of Streptomyces [0.03%]
结核分枝杆菌PknB和CslA在细胞壁形态发生中的作用
Marta Derkacz,Andrew Watson,Akshada Gajbhiye et al.
Marta Derkacz et al.
The bacterial cell wall is essential for maintaining cellular integrity and defining the mode of growth, with different species adopting distinct strategies for cell wall synthesis and remodelling. Streptomyces are filamentous bacteria pred...
Zachery R Lonergan,Sarah L Weisflog,Matthew Scurria et al.
Zachery R Lonergan et al.
The radical nitric oxide (·NO) is short-lived but has imprinted itself on many aspects of physiology and disease. ·NO's rapid production and consumption, coupled with its intrinsic reactivity, drive its biological importance; thus, defini...
Protein STM3547 From Salmonella typhimurium Is a Phosphofructose Kinase B-Type Enzyme With Ribose Kinase Activity [0.03%]
大肠杆菌STM3547蛋白是一种具有核糖激酶活性的磷酸果糖激酶B类酶
Regan D McCormick,Aatif A Jabbar,Jorge C Escalante-Semerena
Regan D McCormick
The first step in the metabolic utilization of ribose is the phosphorylation of its 5' hydroxyl group. The enteropathogenic bacterium Salmonella enterica subsp. enterica sv. Typhimurium str. LT2 (hereafter S. Typhimurium) has two known enzy...
The Absence of E. coli Nucleoid-Associated Protein FIS at Low Temperature Leads to an Adaptation Response That Causes a Shift Towards Genome Compaction in Small Rods [0.03%]
低温下缺少大肠杆菌染色体相关蛋白FIS导致的适应性反应使小杆状菌株基因组趋于紧密化
Pamela G Jones
Pamela G Jones
In contrast to the rod shape at 37°C, the morphology of Escherichia coli cells at temperatures just above the minimum temperature of growth is small rods. A study was initiated to determine the requirement of nucleoid-associated protein FI...