Pharmacokinetics of Ceftiofur-Related Residues in Rabbits After Single Intravenous and Intramuscular Administration [0.03%]
单次静脉和肌肉注射头孢噻呋后家兔的药动学研究
Yan-Yan Gao,Ijaz Ahmad,Fan Yang
Yan-Yan Gao
Ceftiofur is a third-generation cephalosporin widely used in veterinary medicine; however, pharmacokinetic data in rabbits remain limited. This study aimed to characterize the pharmacokinetics of ceftiofur in rabbits following single intrav...
Pharmacokinetics of Moxidectin in Bare-Nosed Wombats (Vombatus ursinus) After Intravenous, Sub-Cutaneous and Transdermal Administration [0.03%]
莫西菌素在裸鼻 wombat (Vombatus ursinus) 静脉内、皮下和经皮给药后的药动学研究
E K Stott,L F Skerratt,T Whittem et al.
E K Stott et al.
The anti-parasitic drug moxidectin is a frontline treatment for sarcoptic mange in bare-nosed wombats (Vombatus ursinus), a disease causing significant animal welfare issues and instances of local population declines. Despite widespread usa...
Pharmacokinetics of Bexagliflozin After Intravenous and Oral Administration in Cats [0.03%]
经静脉和口服给药后贝格列净在猫体内的药代动力学
Yogini Patel,Sheeva Bhattarai,Céline E Toutain
Yogini Patel
Bexagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, has been developed for feline diabetes mellitus. This study characterized bexagliflozin pharmacokinetics in healthy cats after single intravenous and oral administ...
Pharmacokinetics of 2 mg/kg Bupivacaine in a Rectus Abdominis Sheath Block in Horses [0.03%]
马尾巴阻滞复合腹白线阻滞用于马的站立手术剂量及药代动力学研究
Daniel M Sakai,Yushun Ishikawa,Jessica S Y Im et al.
Daniel M Sakai et al.
Administering large volumes of bupivacaine in the rectus abdominis sheath (RAS) block in horses could cause local anesthetic toxicity. This study aimed to evaluate the pharmacokinetics of 2 mg/kg bupivacaine in RAS blocks and the associated...
Pharmacokinetics of Intramuscularly Administered Ketamine at Subanaesthetic Dosage in Horses [0.03%]
马 horse 静脉和肌内注射亚麻醉剂量ketamine的动力学
Zoë Vandaele,Jana Flyps,Charlotte Cuypers et al.
Zoë Vandaele et al.
Subanaesthetic doses of ketamine (0.5 mg kg-1) provide analgesia in several species, but there is limited information on the pharmacokinetics and clinical effects of intramuscularly administered ketamine in horses. This study investigated t...
Ocular Pharmacokinetics of Topical Chloramphenicol in Dogs: Effects of Concentration and Vehicle Formulation [0.03%]
浓度和剂型对犬结膜囊给药氯霉素眼药水的眼内药动学的影响
Bar Fruchter,Oren Peer,Shir Gonen et al.
Bar Fruchter et al.
This study compared tear film exposure and retention of four chloramphenicol ophthalmic formulations in dogs, evaluating the effects of drug concentration (0.2% to 5%) and vehicle type (solution vs. ointment). Eight healthy dogs were enroll...
Pharmacokinetics, Safety Assessment and Residue Kinetics of Emamectin Benzoate in Rainbow Trout, Oncorhynchus mykiss (Walbaum, 1792) [0.03%]
阿维菌素在虹鳟鱼体内药代动力学、安全性和消解试验研究
Richa Pathak,Neetu Shahi,Prasanna Kumar Patil et al.
Richa Pathak et al.
Emamectin benzoate (EB) is widely used in aquaculture to control ectoparasites. The study evaluated the pharmacokinetics, biosafety, and muscle residue depletion of EB. In pharmacokinetics, following administration of a single oral dose of ...
Effects of Oral Single-Dose Empagliflozin on Urinary Glucose, Serum β-Hydroxybutyrate, and Plasma Empagliflozin Concentrations in Healthy Adult Dogs [0.03%]
恩格列净单次给药对健康成年犬尿糖、血清β-羟丁酸及 plasma 恩格列净浓度的影响
Andrea D Plá Gutierrez,M Lynne OSullivan,Etienne Côté et al.
Andrea D Plá Gutierrez et al.
Empagliflozin is a sodium-glucose cotransporter-2 inhibitor used for treating humans with heart failure, among other conditions. This drug could have applications in veterinary cardiology, but whether empagliflozin has biological effects in...
Proposed Meropenem Breakpoints for Interpretation of Antimicrobial Susceptibility Testing of Bacteria Isolated From Dogs [0.03%]
用于解释犬分离菌药敏试验的美罗培南 breakpoint 的建议
Mark G Papich,Marilyn N Martinez
Mark G Papich
Meropenem is a carbapenem antibiotic used infrequently in veterinary medicine. However, antimicrobial susceptibility testing standards are needed to monitor for resistance caused by carbapenem resistant Enterobacterales (CRE). The Clinical ...
Perceptions of Medications and Supplements by U.S. Dog-Interested Members of the Public and Final-Year Veterinary Students [0.03%]
美国爱狗人士和兽医专业学生对药物和补充剂的看法
Sidonie T Gallinger,Johanna C Heseltine,Kate Illing et al.
Sidonie T Gallinger et al.
Veterinary graduates must be prepared to educate clients about medications and supplements. We surveyed 1955 Dog Aging Project newsletter recipients and 40 final-year veterinary students at Texas A&M College of Veterinary Medicine and Biome...