Validation and Evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers [0.03%]
用于检测家禽羽毛上抗生素残留的侧向流动试验的验证与评估
Sophie Hedges,Sophie Mompelat,Dominique Hurtaud-Pessel et al.
Sophie Hedges et al.
Persistence of antimicrobial drugs (AMDs) administered to poultry is longer in feathers than in edible tissues. Hence, poultry feathers are a suitable matrix to investigate historical exposure contributing to antimicrobial resistance, since...
Ilse R Dubbelboer,Lena Olsén,Lena Pelander et al.
Ilse R Dubbelboer et al.
The pharmacokinetics and plasma protein binding of amoxicillin in cats has not been thoroughly investigated. In a single-group sequential designed experimental study, amoxicillin was administered to six healthy cats intravenously, orally, a...
Pharmacokinetics of Chloramphenicol and Chloramphenicol Glucuronide in Horses Following Administration Per Rectum or via Nasogastric Intubation [0.03%]
直肠给药和鼻管投予氯霉素和氯霉素葡萄糖醛酸酯在 horse 体内的药代动力学研究
B Sayler,A J Manship,J Davis et al.
B Sayler et al.
Chloramphenicol is a broad-spectrum antibiotic used in equine practice. It is known to produce adverse effects of hyporexia/anorexia after oral administration. Administration per rectum (PR) could mitigate the appetite suppression seen with...
Routine Doses of Enrofloxacin Achieve Pharmacodynamic Target Likely to Treat Susceptible and Susceptible Dose-Dependent Bacterial Infections in Critically Ill Dogs [0.03%]
环丙沙星常规剂量在危重病犬体内的药动学指标有望治疗敏感菌和剂量依赖性敏感菌感染
Robert Goggs,Sarah Robbins,Julie Menard et al.
Robert Goggs et al.
The fluoroquinolones, particularly enrofloxacin, are frequently used to treat life-threatening bacterial infections in small animal emergency and critical care practice. Achieving therapeutic plasma concentrations is essential for effective...
Penicillin and Gentamicin Concentrations in the Uterine Fluid of Non-Pregnant Mares Following a Single Intrauterine Infusion [0.03%]
一次性宫腔给药非妊娠母马子宫液中青霉素和庆大霉素的浓度分布研究
C Scott Bailey,Theresa M Beachler,Jonathan P Mochel et al.
C Scott Bailey et al.
Despite their widespread clinical use, there is limited pharmacokinetic data for many equine intrauterine antimicrobials. This study aimed to measure the concentration of gentamicin and penicillin in the uterine fluid of mares following inf...
Dissolution Characteristics of Split and Crushed Levetiracetam Extended-Release Tablets in Comparison With Immediate-Release Formulation [0.03%]
比较利培酮缓释片与即释制剂的溶出特征（裂开或研碎后）
Alejandro Mondino,Julie A Nettifee,Mark G Papich et al.
Alejandro Mondino et al.
Levetiracetam (LEV) is a commonly used antiseizure medication in dogs, available in immediate-release (LEV-IR) and extended-release (LEV-XR) formulations. LEV-XR improves owner compliance with less frequent dosing, but its lowest concentrat...
Incorporating the Competencies of Evidence-Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US [0.03%]
将基于证据的兽医医学能力（以药物治疗为主）融入美国一所兽医教学医院的小动物皮肤病和食品动物外科学临床轮转中
Virginia R Fajt,Adam P Patterson,Dusty Nagy et al.
Virginia R Fajt et al.
Building the skills and knowledge necessary to practice evidence-based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the bio...
A Randomized, Blinded, Placebo-Controlled Crossover Study of the Pharmacokinetics and Pharmacodynamics of Naloxone, Naltrexone, and Nalmefene in Methadone-Sedated Working Dogs [0.03%]
一项有关纳洛酮、纳曲酮和纳美芬在美沙酮镇静工作犬体内药代动力学和药效学的随机盲法对照交叉研究
Travis Mills,Mary A Robinson,Ciara Barr et al.
Travis Mills et al.
A randomized, blinded, placebo-controlled crossover study was performed with eight professional working dogs to evaluate the pharmacokinetics and pharmacodynamics of three opioid reversal agents. Following sedation with 1 mg kg-1 methadone ...
Planned Approach and Implementation of Pharmacology Teaching in the Bachelor's Veterinary Nursing Programme in Sweden [0.03%]
瑞典兽医护理学士课程中药理学教学的计划与实施
Lena Olsén,Ann-Christin Blomkvist
Lena Olsén
Veterinary Nurses play a key role in handling drugs and perform medication treatments, thus pharmacological knowledge is essential. The veterinary nurses' role varies widely worldwide but does not include the prescription of drugs. Neverthe...
The Impact of Vatinoxan on the Concentrations of Medetomidine, Midazolam, and Fentanyl in Central Nervous System After Subcutaneous Co-Administration in Rats [0.03%]
瓦西诺酮对皮下联合给药后大鼠脑内美托咪啶、咪达唑仑和芬太尼浓度的影响
Juhana Honkavaara,Emily Lindh,Anna Meller et al.
Juhana Honkavaara et al.
Our aim was to investigate whether vatinoxan, a peripherally acting alpha2-adrenoceptor antagonist, would affect the concentrations of medetomidine, midazolam, and fentanyl in the central nervous system after subcutaneous co-administration....