Does Hypoxic Burden Better Explain Sex Differences in Functional Impairments Than Apnoea-Hypopnoea Index in Obstructive Sleep Apnoea? [0.03%]
低氧负荷较呼吸暂停低通气指数更能解释阻塞性睡眠呼吸暂停功能损害的性别差异？
Urvashi Nanda,Yu Sun Bin,Philip de Chazal et al.
Urvashi Nanda et al.
Women with obstructive sleep apnoea (OSA) report more severe functional impairments than men, despite lower apnoea-hypopnoea index (AHI) values. This raises questions about the adequacy of AHI for capturing OSA severity. We explored sex dif...
Risk Factors for Motor Vehicle Accidents in Obstructive Sleep Apnoea Patients With Long-Term Continuous Positive Airway Pressure Therapy [0.03%]
长期接受持续气道正压治疗的阻塞性睡眠呼吸暂停患者发生机动车事故的风险因素
Jere Jaakkola,Thijs Feuth,Ulla Anttalainen et al.
Jere Jaakkola et al.
In this study, we aim to establish risk factors for sleepiness while driving, motor-vehicle accidents and near miss incidents in obstructive sleep apnoea patients with long-term continuous positive airway pressure (CPAP) therapy. We perform...
Chronic Sleep Irregularity Is Common, Persistent, and Associated With Poorer Sleep Health [0.03%]
慢性睡眠不规律普遍且持久，并与较差的睡眠健康状况相关
Colby D Jones,Bastien Lechat,Daniel Windred et al.
Colby D Jones et al.
Sleep irregularity, characterised by inconsistent sleep duration and timing, is increasingly linked to adverse health outcomes including hypertension. However, the persistence and long-term effects of irregular sleep remain unclear, largely...
Telemedicine Consultation as Diagnostic Triage for Adult and Children With Suspected Narcolepsy: A Reliability and Diagnostic Accuracy Study [0.03%]
针对疑似发作性睡病成人和儿童的远程医疗咨询作为诊断分流的方法：一项关于可靠性和诊断准确性的研究
Luca Vignatelli,Fabio Pizza,Stefano Vandi et al.
Luca Vignatelli et al.
This study aimed at assessing the inter-procedural reliability (compared to the in-office consultation) and the diagnostic accuracy (compared to the reference standard) of the telemedicine consultation to guide the diagnostic workup of adul...
Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof-Of-Concept Study of Alixorexton [0.03%]
针对特发性过度睡眠症和嗜睡症的食欲素2受体：一项关于奥拉克索通的Ⅰb期概念验证性随机研究
Ronald R Grunstein,Brendon J Yee,Julia L Chapman et al.
Ronald R Grunstein et al.
Idiopathic hypersomnia (IH) and narcolepsy type 2 (NT2) are central disorders of hypersomnolence characterised by excessive daytime sleepiness and substantial functional burden. Narcolepsy type 1 (NT1), defined by orexin deficiency, serves ...
Exploring the Relationship Between Thyroid Hormones and Obstructive Sleep Apnea Severity in Euthyroid Patients [0.03%]
甲状腺功能正常患者的甲状腺激素与阻塞性睡眠呼吸暂停严重程度关系的研究
Marsida Teliti,Laura Croce,Caterina Pronzato et al.
Marsida Teliti et al.
Obstructive sleep apnea, characterised by intermittent hypoxia and sleep fragmentation, may influence thyroid hormone regulation. However, evidence regarding thyroid function in obstructive sleep apnea remains inconsistent, particularly for...
Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort [0.03%]
警觉性受损与慢性焦虑相关：一项来自三级大学中心队列的研究
Anice Borjon,Lucie Bobin,François Ricordeau et al.
Anice Borjon et al.
The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may infl...
Distinct EEG Features and Sleep/Wake Behaviour Predict Anxiety Phenotypes in Mice [0.03%]
不同的EEG特征和睡眠/清醒行为可预测小鼠的焦虑表型
A Altunkaya,K M Mengel,M V Schmidt et al.
A Altunkaya et al.
Preoperative anxiety is a prevalent clinical problem linked to adverse surgical outcomes, including elevated pain, prolonged hospital stays and increased risk of postoperative delirium. Current assessments rely heavily on subjective measure...
The Relative Contributions of Arousal Presence and Arousal Intensity to Post-Respiratory-Event Ventilation in Obstructive Sleep Apnea [0.03%]
阻塞性睡眠呼吸暂停患者呼吸事件后通气的自主神经机制研究唤醒的存在和觉醒强度的作用大小
Junyan Zhang,Dwayne Mann,Timo Leppänen et al.
Junyan Zhang et al.
Obstructive sleep apnea (OSA) is characterised by cyclical respiratory events followed by hyperpneic breaths that frequently coincide with cortical arousals. Whilst this post-event hyperventilation partly reflects accumulated respiratory st...
Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk [0.03%]
夜间睡眠时长的改变及其与认知衰退和痴呆风险之间的关系
Marieclaire Overton,Sölve Elmståhl,Rani Basna
Marieclaire Overton
This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study 'Good Aging in Skåne' (Mage = 68.4) with normal base...