Mild increase of temperature from the thermoneutral zone inhibits reproductive activation in Syrian hamsters through epigenetic inhibition [0.03%]
温和升高的温度通过表观遗传抑制作用抑制叙利亚仓鼠的生殖激活
Lalsiamkima Hnamler,Amit Kumar Trivedi
Lalsiamkima Hnamler
The rapid increase in urbanization is drastically altering the habitat composition of the wild population. Urbanization is predominantly changing the landscape, composition of flora and fauna, availability of night light, and the rise in te...
Telotristat ethyl affects tumour-fibroblast crosstalk in small intestinal neuroendocrine tumours [0.03%]
_telotristat乙醇胺影响小肠神经内分泌肿瘤的肿瘤-成纤维细胞交叉谈话
Harry Hodgetts,Maria Castanho Martins,Luohai Chen et al.
Harry Hodgetts et al.
Small intestinal neuroendocrine tumours (SI-NETs) are associated with mesenteric fibrosis, which causes significant morbidity and mortality. Telotristat ethyl was developed to treat carcinoid syndrome in SI-NET patients. Recent studies indi...
Three-dimensional quantification of oxytocin neurons in the hypothalamic paraventricular nucleus reveals sex- and subregion-specific differences in two genetic mouse models of autism [0.03%]
两种自闭症遗传小鼠模型中下丘脑室旁核催产素神经元的三维定量分析揭示了性别和亚区特异性的差异
Aishwarya Patwardhan,Siyao Li,Jessica Chen et al.
Aishwarya Patwardhan et al.
Oxytocin (OXT), a neuropeptide hormone essential to a wide range of social functions, has drawn increasing attention as a crucial contributor to the neurobiology of autism spectrum disorder (ASD). Central OXT system disruptions have been re...
Annual rhythms of thyroid hormone signaling: Environmental influences on thyroid function and disease implications [0.03%]
甲状腺激素信号的年度节奏：环境对甲状腺功能和疾病的影响
Jiaqi Liu,Zixuan Wang,Hanyu Wang et al.
Jiaqi Liu et al.
Hormones within the hypothalamic-pituitary-thyroid (HPT) axis play a central role in acclimatization, dynamically responding to nutritional, thermal, and photoperiodic cues to coordinate metabolic, thermoregulatory, and reproductive functio...
Controversies in NEN: An ENETS position statement on the management of locally advanced neuroendocrine neoplasia of the small intestine and pancreas without distant metastases [0.03%]
小肠和胰腺局部晚期神经内分泌肿瘤的诊疗争议及ENETS立场声明（无远处转移）
M E T Tesselaar,S Partelli,A J A T Braat et al.
M E T Tesselaar et al.
Locally advanced neuroendocrine neoplasms (NENs) are defined by extensive local invasion in the absence of distant metastases, although specific definitions may vary among study groups. While most patients with NENs present with localized o...
Kirk D Haan,Thomas E Fisher
Kirk D Haan
Osmoregulation is an essential homeostatic process that maintains the osmolality of the extracellular fluid (ECF) close to a physiological setpoint. Vasopressin (VP) plays a key role in osmoregulation and is secreted by the magnocellular ne...
Juan Manuel Riano Gomez
Juan Manuel Riano Gomez
Benzophenones (BPs) are widely used as ultraviolet (UV) filters in personal care products, plastics, and food packaging. Although they serve as effective photoprotective agents, growing evidence suggests that BPs can act as endocrine-disrup...
Mechanisms of intrinsic osmolality and sodium detection by magnocellular neurosecretory neurons [0.03%]
大细胞神经分泌神经元检测固有渗透压和钠的机制
Sandra Salgado-Mozo,Anzala Murtaz,Joshua C Wyrosdic et al.
Sandra Salgado-Mozo et al.
The maintenance of extracellular fluid (ECF) osmolality and sodium concentration ([Na+]o) near optimal "set point" values sustains physiological functions and prevents pathological states such as hypo- and hypernatremia. The peptide hormone...
Oxytocin neural responses distinguish social novelty from familiarity but not kin from non-kin in male spiny mice [0.03%]
催产素神经反应区分刺毛鼠雄性的社会新颖性与熟悉性但不能区分亲属与非亲属
Christian Janmil Esquilin-Rodriguez,Brandon A Fricker,Aubrey M Kelly
Christian Janmil Esquilin-Rodriguez
In most species, individuals must be able to identify threats, peers, and potential mates to survive. The distinction of kin from non-kin and novel conspecifics from familiars is essential to the successful categorization of these identitie...
Sleep in neurodegenerative diseases: A focus on melatonin, melanin-concentrating hormone and orexin [0.03%]
神经退行性疾病中的睡眠障碍：关于褪黑素、促黑激素和下丘脑分泌素的研究焦点
Simon J Guillot,Pierre-Hervé Luppi,Luc Dupuis et al.
Simon J Guillot et al.
Sleep and circadian rest-activity rhythm alterations are recognised as inherent clinical features of various neurodegenerative diseases. Traditionally viewed as secondary manifestations of neurodegeneration, recent studies have revealed tha...