Dense sampling for mapping pituitary growth dynamics before, during, and after pregnancy [0.03%]
密集采样绘制妊娠前、妊娠中和妊娠后的垂体生长动力学地图
Giorgia Picci,Risha Arora,Hannah Grotzinger et al.
Giorgia Picci et al.
Pregnancy represents a period of profound endocrine activity and neural reorganization. While recent evidence highlights pituitary volume as a biomarker of endocrine dynamics during pregnancy, its precise trajectory (timing and relative mag...
Determinants of incidence trends in pancreatic neuroendocrine neoplasms [0.03%]
胰腺神经内分泌肿瘤发病率变化的影响因素分析
Giuseppe Lamberti,Elisa Andrini,Adriana Di Odoardo et al.
Giuseppe Lamberti et al.
The incidence of pancreatic neuroendocrine neoplasms (NENs) is rising; whether this reflects a true increase in disease occurrence or improved detection remains uncertain. We conducted a retrospective, population-based study using data from...
The intermediate conductance calcium-dependent K+ channel does not contribute to the slow after hyperpolarization in oxytocin and vasopressin hypothalamic magnocellular neurons [0.03%]
中间钙依赖性钾通道不参与血管加压素和缩宫素的大细胞神经元的慢后超极化作用
Levi Shook,Matthew K Kirchner,Elba Campos-Lira et al.
Levi Shook et al.
Vasopressin (VP) magnocellular neurosecretory neurons of the hypothalamic supraoptic nucleus (SON) are critical regulators of renal water retention and vascular tone. VP neurons undergo detrimental plastic changes in cardiovascular diseases...
Blunted arginine vasopressin secretion in individuals experiencing a major depressive episode with comorbid post-traumatic stress disorder: Results from an exploratory study using copeptin as a surrogate marker [0.03%]
伴有创伤后应激障碍的重大抑郁发作患者的精氨酸加压素分泌不足：采用copeptin作为替代标记物的探索性研究结果
Hiroe Hu,Yoojin Lee,Alaina N Tillman et al.
Hiroe Hu et al.
Arginine vasopressin (AVP) modulates stress responsivity and social-affective behaviors, but its role in mood and trauma-related disorders remains poorly defined due to challenges in peripheral measurement. This study used copeptin, a stabl...
Sexual receptivity increases in synchrony with the ovulatory cycle in female medaka [0.03%]
虹鳉雌鱼的交配受容性与其排卵周期同步出现波动现象
Soma Tomihara,Rinko Shimomai,Mikoto Nakajo et al.
Soma Tomihara et al.
Background: Successful reproduction requires coordinated regulation of gonadal function and sexual behavior. Nonetheless, the mechanisms underlying this coordination in teleosts remain elusive. Here, we aimed to find out ...
Diana Lalitsasivimol,Kalpana D Acharya,Paige L Graney et al.
Diana Lalitsasivimol et al.
During development, there is a significant sex difference in the expression of progestin receptor (PR) in the medial preoptic nucleus (MPN) of rodents. Males express high levels of PR immunoreactivity (PR-ir) in the MPN beginning at embryon...
Genetic inactivation of the CRF1 receptor eliminates age-linked elevation of hippocampal 11β-hydroxysteroid dehydrogenase type 1 activity in female mice [0.03%]
遗传性失活CRF1受体可消除雌性小鼠海马室管膜细胞中年龄依赖性的11β-羟基类固醇脱氢酶Ⅰ型活性升高现象
Julie Brossaud,Alessandro Piccin,Angelo Contarino et al.
Julie Brossaud et al.
Glucocorticoids are produced through activation of the hypothalamic-pituitary-adrenal (HPA) axis, initiated by the release of corticotropin-releasing factor (CRF) from the hypothalamus. CRF acts through two receptor subtypes, CRF1 and CRF2....
Athul R Ramesh,Naveen Nedunchezhian,Md Hasan Ali et al.
Athul R Ramesh et al.
The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypo...
The transition to human fatherhood involves increased brain activation to infant stimuli in regions involved with reward and motivation [0.03%]
人类父亲的角色转换涉及奖励和动机相关脑区在婴儿刺激下的激活增强现象
James K Rilling,Minwoo Lee,Carolyn Zhou et al.
James K Rilling et al.
In species where males provide parental care, the transition to fatherhood involves a shift in life history strategy in the direction of increased parenting and decreased mating effort. In non-human mammals, the transition to parenthood inv...
Josiane do N Silva,Ligia M M de Sousa,Maria E de Sousa et al.
Josiane do N Silva et al.
Neurons in the arcuate nucleus of the hypothalamus (ARH) that coexpress kisspeptin, neurokinin B, and dynorphin (KNDy neurons) are considered the gonadotropin-releasing hormone (GnRH) pulse generator necessary for fertility. KNDy neurons ar...