MicroRNA-23a-3p promotes macrophage M1 polarization and aggravates lipopolysaccharide-induced acute lung injury by regulating PLK1/STAT1/STAT3 signalling [0.03%]
microRNA-23a-3p通过调控PLK1/STAT1/STAT3信号促进巨噬细胞M1极化并加重脂多糖诱导的急性肺损伤
Tao Jiang,Li Sun,Jun Zhu et al.
Tao Jiang et al.
Macrophage polarization is an important effector process in acute lung injury (ALI) induced by sepsis. MicroRNAs (miRNAs) have emerged as important players in regulating ALI process. Here, we showed that elevated microRNA-23a-3p (miR-23a-3p...
Histomorphometric and oxidative evaluation of the offspring's testis from type 2 diabetic female rats treated with metformin and pentoxifylline [0.03%]
二型糖尿病大鼠模型口服二甲双胍和戊四硝酯对子代睾丸组织形态计量学及氧化损伤的影响
Jessica Santana de Oliveira,Alluanan Adelson do Nascimento Silva,Fernanda Carolina Ribeiro Dias et al.
Jessica Santana de Oliveira et al.
Type 2 diabetes mellitus (T2D) during pregnancy is characterized by high levels of reactive oxygen species and pro-inflammatory factors in the placenta. Once these reactive species reach the foetus, they trigger physiological adaptations th...
Pre-analytical processing protocol of breast biopsies affects multigene panel results [0.03%]
乳腺活检的预分析处理方案会影响多基因检测结果
Vanessa Reinaldo Lima,Beatriz da Costa Aguiar Alves,Fernando Luiz Affonso Fonseca et al.
Vanessa Reinaldo Lima et al.
The creation of multigene panels for prognostic and predictive purposes allows a more accurate indication of adjuvant chemotherapy for patients with breast cancer. In a previous study, we reproduced a multigene panel of 21 genes based on th...
Expression of airway smooth muscle contractile proteins in children with acute interstitial pneumonia [0.03%]
急性间质性肺病患儿气道平滑肌收缩蛋白的表达
Fang Cheng,Tao Lu,Yicheng Wang et al.
Fang Cheng et al.
The purpose of the present study was to investigate the expression of α-SMA and SM22α in airway smooth muscle (ASM) of bronchioles from children younger than 14 years who died of acute interstitial pneumonia (AIP). This is based upon the ...
Eda Yildizhan,Burak Veli Ulger,Murat Akkus et al.
Eda Yildizhan et al.
Wound healing is a dynamic process initiated in response to injury. There are many factors that have detrimental effects on the wound healing process. Numerous studies have been conducted for improving wound healing processes. Dexpanthenol ...
Correlations between histological characterizations and methylation statuses of tumour suppressor genes in Wilms' tumours [0.03%]
肾母细胞瘤中肿瘤抑制基因甲基化状态与组织病理特征的相关性研究
Yen-Chein Lai,Meng-Yao Lu,Wen-Chung Wang et al.
Yen-Chein Lai et al.
Wilms' tumour is a solid tumour that frequently occurs in children. Genetic changes in WT1 and epigenetic aberrations that affect imprinted control region 1 in WT2 loci are implicated in its aetiology. Moreover, tumour suppressor genes are ...
lncRNA MIAT targets miR-411-5p/STAT3/PD-L1 axis mediating hepatocellular carcinoma immune response [0.03%]
长链非编码RNA MIAT通过靶向miR-411-5p/STAT3/PD-L1轴介导肝癌的免疫反应
Xiaoxia Zhang,Banglun Pan,Jiacheng Qiu et al.
Xiaoxia Zhang et al.
Emerging evidences have shown that long noncoding RNA (lncRNA) plays an important role in the immune escape of cancer cells. Our previous study has demonstrated that lncRNA MIAT is associated with the immune infiltration of hepatocellular c...
High level of FHL2 exacerbates the outcome of non-small cell lung cancer (NSCLC) patients and the malignant phenotype in NSCLC cells [0.03%]
FHL2高表达加重非小细胞肺癌患者的预后及促进肺腺癌细胞恶性表型的进展
Na Li,Ling Xu,Ji Zhang et al.
Na Li et al.
Non-small cell lung cancer (NSCLC) is a malignant tumour with high mortality. FHL2 has been identified as a biomarker of lung cancer. This research explored the effects of FHL2 expression on NSCLC. NSCLC-associated data sets were collected ...
Transient atrial inflammation in a murine model of Coxsackievirus B3-induced myocarditis [0.03%]
柯萨奇病毒B3诱导的小鼠心肌炎模型中的瞬时房性炎症
Linghe Wu,Mitchell D Fiet,Daan R Raaijmakers et al.
Linghe Wu et al.
Atrial dysfunction is a relatively common complication of acute myocarditis, although its pathophysiology is unclear. There is limited information on myocarditis-associated histological changes in the atria and how they develop in time. The...
Inflammatory response and immunohistochemical characterization of experimental calcium silicate-based perforation repair material [0.03%]
钙硅酸盐根管堵塞材料的炎症反应及其免疫组化特征分析
Hend Okasha,Ashraf M Abu-Seida,Ahmed A Hashem et al.
Hend Okasha et al.
This study compares the immunohistochemical reaction of a new experimental tricalcium silicate perforation repair material to mineral trioxide aggregate (MTA) and Biodentine. A total of 162 mature premolar teeth from 12 dogs were divided in...