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Correlations between histological characterizations and methylation statuses of tumour suppressor genes in Wilms' tumours

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Wilms' tumour is a solid tumour that frequently occurs in children. Genetic changes in WT1 and epigenetic aberrations that affect imprinted control region 1 in WT2 loci are implicated in its aetiology. Moreover, tumour suppressor genes are frequently silenced ... ...