IBD functions as a double-edged sword for food allergy in BALB/c mice model [0.03%]
在BALB/c小鼠模型中，IBD具有双刃剑作用诱导食物过敏现象
Bihua Chen,Yuhong Wu,Huan Wu et al.
Bihua Chen et al.
Inflammatory bowel disease (IBD) and food allergy (FA) increase in tandem, but the potential impact of IBD on FA remains unclear. We sought to determine the role of IBD on FA. We first assessed the changes of FA-related risk factors in dext...
Polygenic TB control and the sequence of innate/adaptive immune responses to infection: MHC-II alleles determine the size of the S100A8/9-producing neutrophil population [0.03%]
多基因结核病控制和感染后固有/适应性免疫反应顺序：MHC-II等位基因决定了产生S100A8/9的中性粒细胞的数量大小
Nadezhda Logunova,Marina Kapina,Alexander Dyatlov et al.
Nadezhda Logunova et al.
Among several quantitative trait loci involved in tuberculosis (TB) control in mice, one was mapped within the chromosome 17 segment occupied by the H2 complex and another within the chromosome 3 segment comprising the S100A8/9 genes, which...
Erythropoietin induces tumour progression and CD39 expression on immune cells in a preclinical model of triple-negative breast cancer [0.03%]
预临床模型中红细胞生成素可诱导三阴性乳腺癌进展和免疫细胞上CD39的表达
Stéphanie Bessoles,Andrada Chiron,Guillaume Sarrabayrouse et al.
Stéphanie Bessoles et al.
The adverse effects observed in some cancer patients treated with erythropoiesis-stimulating agents such as erythropoietin (EPO) might be due to the latter's well-known immunosuppressive functions. Here, we used a mouse model of syngeneic t...
Changing the location of proteins on the cell surface is a promising strategy for modulating T cell functions [0.03%]
调节T细胞功能的一种策略是在细胞表面改变蛋白质的位置
Marianne Strazza,Ruijiang Song,Shannon Hiner et al.
Marianne Strazza et al.
Targeting immune receptors on T cells is a common strategy to treat cancer and autoimmunity. Frequently, this is accomplished through monoclonal antibodies targeting the ligand binding sites of stimulatory or inhibitory co-receptors. Blocki...
Review
Immunology. 2024 Jul 1. DOI:10.1111/imm.13828 2024
PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody-secreting cells from oxidative stress [0.03%]
PCK2通过保护抗体分泌细胞免受氧化应激以维持肠内稳态和防止结肠炎
Kun-Long Duan,Tian-Xiang Wang,Jian-Wei You et al.
Kun-Long Duan et al.
Maintaining intracellular redox balance is essential for the survival, antibody secretion, and mucosal immune homeostasis of immunoglobulin A (IgA) antibody-secreting cells (ASCs). However, the relationship between mitochondrial metabolic e...
IL-10 indirectly modulates functional activity of CD4+CD28null T-lymphocytes through LFA-3 and HLA class II inhibition [0.03%]
IL-10通过抑制LFA-3和HLA-II间接调节CD4+CD28null T淋巴细胞的功能活性
Alejandra García-Torre,Eva Bueno-García,Marco A Moro-García et al.
Alejandra García-Torre et al.
Expansion of CD4+CD28null T-lymphocytes is common in chronic heart failure (CHF) patients. Its ability to produce high levels of proinflammatory cytokines is probably the key role of these cells in CHF. IL-10 is a candidate for limiting CD4...
Correction to "Psychological stress to ovalbumin peptide-specific T-cell receptor transgenic mice impairs the suppressive ability of type 1 regulatory T cell" [0.03%]
题为“心理压力通过T细胞受体转基因小鼠卵清蛋白肽特异性T辅助性T细胞抑制调节性T细胞的能力”的勘误通知书
Published Erratum
Immunology. 2024 Aug;172(4):669-670. DOI:10.1111/imm.13830 2024
Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody [0.03%]
新型单克隆抗体鉴别不同功能的CD8⁺ T细胞亚群
Kantinan Chuensirikulchai,Supansa Pata,Witida Laopajon et al.
Kantinan Chuensirikulchai et al.
The explicit identification of CD8+ T cell subpopulation is important for deciphering the role of CD8+ T cells for protecting our body against invading pathogens and cancer. Our generated monoclonal antibody (mAb), named FE-1H10, recognized...
Ru-Xue Ma
Ru-Xue Ma
Intermittent fasting (IF) refers to periodic fasting routines, that caloric intake is minimized not by meal portion size reduction but by intermittently eliminating ingestion of one or several consecutive meals. IF can instigate comprehensi...
Review
Immunology. 2024 Jun 25. DOI:10.1111/imm.13829 2024
CD5L is upregulated upon infection with Mycobacterium tuberculosis with no effect on disease progression [0.03%]
麻风分枝杆菌感染可以上调CD5L，但其表达水平与疾病进展无关
Marcos S Cardoso,Rute Gonçalves,Liliana Oliveira et al.
Marcos S Cardoso et al.
Tuberculosis (TB) alone caused over a billion deaths in the last 200 years, making it one of the deadliest diseases to humankind. Understanding the immune mechanisms underlying protection or pathology in TB is key to uncover the much needed...