Interactions of NK Cells and Macrophages: From Infections to Cancer Therapeutics [0.03%]
NK细胞与巨噬细胞的相互作用：从感染到癌症治疗
Vishakha Hooda,Alpana Sharma
Vishakha Hooda
The interaction between immune cells brings a consequence either on their role and functioning or the functioning of the other immune cells, modulating the whole mechanistic pathway. The interaction between natural killer (NK) cells and mac...
Review
Immunology. 2024 Dec 30. DOI:10.1111/imm.13886 2024
FOXP3 Transcriptionally Activates Fatty Acid Scavenger Receptor CD36 in Tumour-Induced Treg Cells [0.03%]
FOXP3通过转录激活脂肪酸清除受体CD36在肿瘤诱导的Tregs细胞中发挥功能
Subhanki Dhar,Tania Sarkar,Sayantan Bose et al.
Subhanki Dhar et al.
The host immune system is adapted in a variety of ways by tumour microenvironment and growing tumour interacts to promote immune escape. One of these adaptations is manipulating the metabolic processes of cells in the tumour microenvironmen...
ITGB4/BNIP3 Activates Autophagy and Reduces MHC-I Expression to Mediate Tumour Immune Escape in Pancreatic Cancer Cell Lines [0.03%]
ITGB4/BINP3通过激活自噬和降低MHC-I表达介导胰腺癌细胞系的免疫逃逸
Xianfei Zhou,Fan Yang,Luoshun Huang et al.
Xianfei Zhou et al.
This study attempted to identify the relevant pathways involved in autophagy activation of pancreatic cancer and explore the mechanisms underlying immune evasion. Western blot (WB) was used to detect the expression of ITGB4, BNIP3, autophag...
Blocking Deoxycytidine Kinase in Activated Lymphocytes Depletes Deoxycytidine Triphosphate Pools and Alters Cell Cycle Kinetics to Yield Less Disease in a Mouse Multiple Sclerosis Model [0.03%]
抑制活化淋巴细胞中的脱氧胞苷激酶会耗竭脱氧三磷酸胞苷并改变小鼠自身免疫性疾病模型中的细胞周期动力学以减少疾病发生
Jessica R Salas,K M Ryan,Alyssa O Trias et al.
Jessica R Salas et al.
Autoreactive, aberrantly activated lymphocytes that target myelin antigens in the central nervous system (CNS) are primary drivers of the autoimmune disease multiple sclerosis (MS). Proliferating cells including activated lymphocytes requir...
Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools [0.03%]
核酸内切酶：从原始的免疫守护者到现代生物技术工具
Frank J Hernandez
Frank J Hernandez
The story of nucleases begins on the ancient battlefields of early Earth, where simple bacteria fought to survive against viral invaders. Nucleases are enzymes that degrade nucleic acids, with restriction endonucleases emerging as some of t...
Review
Immunology. 2024 Dec 16. DOI:10.1111/imm.13884 2024
Xin-Hua Yu,Xin-Ning Guo,Kui Li et al.
Xin-Hua Yu et al.
Wnt5a plays an important role in cell development and maturation and is closely associated with various diseases, such as malignant tumours, metabolic disorders, fibrosis, growth and development. Recent studies have shown that Wnt5a express...
Review
Immunology. 2024 Dec 12. DOI:10.1111/imm.13882 2024
Transient Anti-TCRβ mAb Treatment Induces CD4+ T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus [0.03%]
抗TCRβ单克隆抗体瞬时治疗诱导小鼠系统性红斑狼疮模型中CD4+T细胞衰竭并延长生存期
Nancy Mize Gonzalez,Dawei Zou,Zihua Zeng et al.
Nancy Mize Gonzalez et al.
T cells play a critical role in the pathogenesis of systemic lupus erythematosus (SLE). Chronic T cell receptor (TCR) signalling induces T cell exhaustion, characterised by reduced capacity to induce tissue damage. Here, we investigated the...
RETRACTION: 5-lipoxygenase Knockout Mice Exhibit a Resistance to Acute Pancreatitis Induced by Cerulein [0.03%]
撤稿：5-脂氧合酶基因敲除小鼠对胰岛素诱导的急性胰腺炎具有抗性
S. Cuzzocrea, A. Rossi, I. Serraino, R. Di Paola, L. Dugo, T. Genovese, D. Britti, G. Sciarra, A. De Sarro, A. P. Caputi, and L. Sautebin, "5-lipoxygenase Knockout Mice Exhibit a Resistance to Acute Pancreatitis Induced by Cerulein," Immuno...
Retraction of Publication
Immunology. 2024 Dec 5. DOI:10.1111/imm.13876 2024
RETRACTION: Peroxynitrite-mediated DNA Strand Breakage Activates Poly (ADP-ribose) Synthetase and Causes Cellular Energy Depletion in Carrageenan-induced Pleurisy [0.03%]
撤销论文：聚阴离子介导的dna断裂激活 poly（adp-核糖） synthetase 和卡拉胶诱导性胸膜炎细胞能量丧失
S. Cuzzocrea, A. P. Caputi, and B. Zingarelli, "Peroxynitrite-mediated DNA Strand Breakage Activates Poly (ADP-ribose) Synthetase and Causes Cellular Energy Depletion in Carrageenan-induced Pleurisy," Immunology 93, no. 1 (1998): 96-101, ht...
Retraction of Publication
Immunology. 2024 Dec 5. DOI:10.1111/imm.13877 2024
IRF5 Controls Plasma Cell Generation and Antibody Production via Distinct Mechanisms Depending on the Antigenic Trigger [0.03%]
IRF5通过不同的机制控制浆细胞的生成和抗体的产生，取决于抗原刺激类型
Bharati Matta,Jenna Battaglia,Margaret Lapan et al.
Bharati Matta et al.
Elevated levels of serum autoantibodies are a hallmark of systemic lupus erythematosus (SLE) and are produced by plasma cells in response to a variety of antigenic triggers. In SLE, the triggers are complex and may include both T cell-depen...