FUS::CREM-rearranged malignant epithelioid neoplasm mimicking neuroendocrine neoplasm of unknown primary [0.03%]
FUS::CREM重排的恶性上皮样肿瘤模仿原发灶不明的神经内分泌肿瘤
Pieter Demetter,Ahmad Awada,Philippe Aftimos et al.
Pieter Demetter et al.
Nuclear morphology in breast lesions: refining its assessment to improve diagnostic concordance [0.03%]
乳腺病变的核形态:完善其评估以提高诊断一致性和准确性
Ayaka Katayama,Michael S Toss,Matthew Parkin et al.
Ayaka Katayama et al.
Aims: Although evaluation of nuclear morphology is important for the diagnosis and categorisation of breast lesions, the criteria used to assess nuclear atypia rely upon the subjective evaluation of several features that ...
Interobserver agreement in the diagnosis of anal dysplasia: comparison between gastrointestinal and gynaecological pathologists and utility of consensus conferences [0.03%]
肛部异型增生诊断中的观察者间一致性:胃肠病和妇科病理学家的对比及共识会议的作用
Sohaib Abu-Farsakh,Michael G Drage,Aaron R Huber et al.
Sohaib Abu-Farsakh et al.
Aims: Management of anal dysplasia relies upon the accurate diagnosis of anal biopsy specimens. As institutions move towards subspecialty signout (SSSO), decisions must be made regarding whether to assign anal biopsies to...
Comparative Study
Histopathology. 2022 Mar;80(4):648-655. DOI:10.1111/his.14578 2022
A comparative study of AJCC and the modified staging system in pT2/pT3 penile squamous cell carcinoma - a validation on an external data set [0.03%]
AJCC与改良分期系统在pT2/pT3阴茎鳞状细胞癌中比较研究 - 外部数据集验证研究
Akash P Sali,Gagan Prakash,Stênio de Cássio Zequi et al.
Akash P Sali et al.
Aims: The recent changes in the American Joint Commission on Cancer, 8th edition (AJCC-8E) pT2 and pT3 tumour definitions for penile cancer need robust validation studies. A recent study redefined and modified the pT2 and...
Comparative Study
Histopathology. 2022 Feb;80(3):566-574. DOI:10.1111/his.14575 2022
Development of a semi-automated method for tumour budding assessment in colorectal cancer and comparison with manual methods [0.03%]
结肠直肠癌肿瘤芽评估的半自动方法的发展及其与手动方法的比较
Natalie C Fisher,Maurice B Loughrey,Helen G Coleman et al.
Natalie C Fisher et al.
Aims: Tumour budding (TB) is an established prognostic feature in multiple cancers but is not routinely assessed in pathology practice. Efforts to standardise and automate assessment have shifted from haematoxylin and eos...
Comparative Study
Histopathology. 2022 Feb;80(3):485-500. DOI:10.1111/his.14574 2022
The prognostic significance of pleomorphism in gastrointestinal stromal tumours [0.03%]
胃肠道间质肿瘤中多形性的预后意义
Raymond A Isidro,Jason L Hornick
Raymond A Isidro
Aim: Gastrointestinal stromal tumours (GISTs) typically show uniform nuclear morphology, with spindle cell, epithelioid or mixed histology. Risk of progression in GIST is estimated based on anatomical site, tumour size an...
Sporadic superficial angiomyxomas demonstrate loss of PRKAR1A expression [0.03%]
散发性浅表性血管黏液瘤显示PRKAR1A表达丧失
Farhaan Hafeez,Andrew C Krakowski,Christine G Lian et al.
Farhaan Hafeez et al.
Superficial angiomyxomas are cutaneous mesenchymal tumours that typically present clinically as slow-growing, solitary, asymptomatic nodules that can occur at any age. Histopathologically, these dermal and subcutaneous tumours are character...
Lessons learnt from MDM2 fluorescence in-situ hybridisation analysis of 439 mature lipomatous lesions with an emphasis on atypical lipomatous tumour/well-differentiated liposarcoma lacking cytological atypia [0.03%]
439例成熟脂样病变MDM2荧光原位杂交分析的经验教训,特别强调了缺乏细胞异型性的非典型脂瘤样肿瘤/分化良好的脂肪肉瘤
Ana Cristina Vargas,Christopher Joy,Alison L Cheah et al.
Ana Cristina Vargas et al.
Aims: Amplification of the murine double minute-2 (MDM2) gene, which is usually detected with fluorescence in-situ hybridisation (FISH), is the key driving event for atypical lipomatous tumours (ALTs)/well-differentiated ...
Measuring depth of invasion of submucosa - invasive adenocarcinoma in oesophageal endoscopic specimens: how good are we? [0.03%]
如何测量食道内镜标本中粘膜下层浸润深度:我们的技术有多好?
Dipti M Karamchandani,Raul S Gonzalez,Maria Westerhoff et al.
Dipti M Karamchandani et al.
Aims: Emerging data support that submucosa-invasive (pT1b) esophageal adenocarcinomas are cured via endoscopic resection, provided that invasion measures ≤500 μm, they lack other histological features predictive of noda...