CD71 expression in Rosai-Dorfman disease: a useful adjunct marker in the differential diagnosis of histiocytic proliferations [0.03%]
CD71在Rosai-Dorfman病中的表达:与组织细胞增生性疾病鉴别诊断相关的有用辅助标记物
Nurfiza N Ladak,Kseniya Petrova-Drus,Meera R Hameed et al.
Nurfiza N Ladak et al.
Aims: Accurate diagnosis of histiocytosis remains challenging due to overlapping morphologic and immunophenotypic features among subtypes, including Langerhans cell histiocytosis (LCH), Erdheim-Chester disease/xanthogranu...
Characterizing pseudoangiomatous stromal hyperplasia (PASH) of the breast [0.03%]
乳腺类血管瘤样硬化增生(PASH)的特征分析
Rahul Koshy,Pragya Virendrakumar Jain,Julie M Jorns
Rahul Koshy
Aims: To investigate the associated histopathology and immunohistochemical (IHC) profile of pseudoangiomatous stromal hyperplasia (PASH) of the breast in a large, contemporary cohort. ...
Ossifying spindled and epithelioid tumour: Expanding the clinical and morphologic spectrum of a recently described entity [0.03%]
骨化的纺锤体和上皮样肿瘤:最近描述的一种疾病的临床和形态学谱系的扩展
Rayan M Sibira,Benjamin F Smith,Amy Davis et al.
Rayan M Sibira et al.
Background: Ossifying spindled and epithelioid tumour (OSET) is a recently defined soft tissue neoplasm with characteristic features, including a peripheral shell of bone or pseudocapsule, keratin expression, and indolent...
Real-world prevalence of PD-L1 positivity in early-stage/metastatic triple-negative breast cancer: primary results and pathology insights from the global retrospective observational VANESSA study [0.03%]
早期和晚期三阴性乳腺癌的PD-L1阳性真实世界患病率:全球性的回顾性观察研究VANESSA的主要结果和病理学见解
Corrado DArrigo,Sitki Tuzlali,Romualdo Barroso-Sousa et al.
Corrado DArrigo et al.
Aim: To understand whether the worldwide implementation of PD-L1 testing in triple-negative breast cancer (TNBC) can be achieved in routine clinical practice. ...
Changes in the 6th edition of the World Health Organization classification of tumours of the digestive system [0.03%]
世界卫生组织消化系统肿瘤分类第六版的更新变化
Mark J Arends,Irene Esposito,Anthony J Gill et al.
Mark J Arends et al.
The 6th Edition of the WHO Classification of Digestive System Tumours represents a significant update to the 5th edition. It integrates pathological, new molecular, and clinical insights to refine the taxonomy of digestive system neoplasms....
Roselyne Choiniere,Willem Pa Boellaard,Geert Jlh van Leenders
Roselyne Choiniere
Background and objective: Occult germ cell neoplasia in situ (GCNIS) can occur in testicular biopsies prompted by male infertility with or without concomitant contralateral tumour. Immunohistochemistry can improve the dia...
Clinicopathological and molecular genetic characteristics of Epstein-Barr virus-positive small cell neuroendocrine carcinoma of the nasopharynx [0.03%]
鼻咽部EB病毒阳性的小细胞神经内分泌癌的临床病理和分子遗传学特征
Lu Jian-Ping,Xie Yun-Li,Wang Xiao-Jiang et al.
Lu Jian-Ping et al.
Background: Epstein-Barr virus (EBV)-positive small cell neuroendocrine carcinoma of the nasopharynx (SCNEC-nasopharynx) is exceptionally rare and aggressive, with poorly characterized molecular features. ...
Paula Toro,Clifton Fulmer,Erica Savage et al.
Paula Toro et al.
Aims: Human papillomavirus (HPV) is the most common sexually transmitted disease in the United States. HPV-associated invasive anorectal adenocarcinoma has been previously described. In this study, we report the clinicopa...
Malignant struma ovarii: Advances in molecular pathogenesis, classification, diagnosis and treatment [0.03%]
恶性卵巢甲状腺肿的分子病理学、分类、诊断及治疗进展
Wanrun Lin,Xin Zhou,Yudong Wang et al.
Wanrun Lin et al.
Malignant struma ovarii (MSO) is an extremely rare ovarian teratoma containing malignant thyroid tissue, typically presenting in middle-aged women. Molecularly and histologically, MSO mirrors thyroid carcinoma and includes analogous subtype...
Genomic and clinicopathological characteristics of low oncotype recurrent score breast cancers with subsequent metastasis [0.03%]
低Oncotype再发分数乳腺癌伴随后期转移的基因组和临床病理特征
Liu Liu,Stephanie L Graff,Sean Hacking et al.
Liu Liu et al.
Aims: Oncotype DX has played a critical role in guiding treatment decisions for hormone receptor (HR)-positive, HER2-negative early-stage breast cancer. Clinically, a subset of patients with low Oncotype recurrent score (...