The OLGIMA system for gastric cancer risk assessment. A useful method based on the histological Sydney consensus [0.03%]
悉尼共识胃病理组织学意见下的胃癌风险评估系统OLGIMA及其临床应用价值评估
Pedro Genaro Delgado Guillena,Miriam Cuatrecasas,Sheyla Montori et al.
Pedro Genaro Delgado Guillena et al.
Introduction: The risk stratification of gastric cancer (GC) is graded by assessing well-established precursor lesions, glandular atrophy (GA), and intestinal metaplasia (IM), resulting in both the operative link on gastr...
Isolated morular squamous metaplasia in endometrial biopsies and curettings: is there a role for repeated sampling? [0.03%]
子宫内膜活检和刮宫标本中孤立的瘤样鳞状上皮化生的临床意义：有必要重复取材吗？
Valentina Zanfagnin,Lawrence Hsu Lin,Kyle M Devins et al.
Valentina Zanfagnin et al.
Aims: Endometrial atypical hyperplasia and low-grade endometrioid carcinoma are often associated with morular squamous metaplasia. Limited evidence suggests that the finding of isolated morular squamous metaplasia without...
Rethinking Gleason pattern quantification in predicting metastasis: results of 20 years of follow-up in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer [0.03%]
格利森模式量化在预测前列腺癌转移中的再思考：欧洲前列腺癌筛查随机研究的鹿特丹部分20年的随访结果
Lisa J Kroon,Sebastiaan Remmers,Ivo I de Vos et al.
Lisa J Kroon et al.
Introduction: The Gleason grading system for prostate cancer (PCa) is based on the proportions of Gleason patterns (GP) 3-5. While pure GP3 has minimal metastatic potential, it is unclear whether GP3 quantity in the prese...
A morphomolecular study of 175 'USP6-associated neoplasms': The USP6 fusion partner strongly depends on morphology and location [0.03%]
175例XPO018/USP6肿瘤的形态分子学研究：USP6融合伴侣强烈依赖于肿瘤的形态和发生部位
Fleur Cordier,Jo Van Dorpe,Raf Sciot et al.
Fleur Cordier et al.
Context: Nodular fasciitis (NF), myositis ossificans/fibro-osseous pseudotumor of the digits (MO/FP) and aneurysmal bone cyst (ABC) are grouped under the category of 'USP6-associated neoplasms' (UANs) due to their shared ...
Transcription factor-based subtype assignment in pulmonary large cell neuroendocrine carcinoma [0.03%]
基于转录因子的肺大细胞神经内分泌癌亚型分配
Yin P Hung,Komson Wannasai,Catherine B Meador et al.
Yin P Hung et al.
Aims: Pulmonary large cell neuroendocrine carcinoma (LCNEC) can be difficult to diagnose due to histological overlap with small cell lung carcinoma (SCLC). SCLC comprises multiple transcription factor-based subtypes. We a...
Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature [0.03%]
睾丸颗粒细胞瘤类似于卵巢同名肿瘤，极为罕见：多中心系列研究及文献综述
Costantino Ricci,Dario de Biase,Thais Maloberti et al.
Costantino Ricci et al.
Aims: Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical-pathological differences with their ovarian counterparts. In a limited number of prior studies, FOXL2 p.Cys134Trp, the hallmark mole...
Acellular mucin pools and neutrophil-to-lymphocyte ratio: unveiling hidden aggressiveness in pathological complete response after chemoradiotherapy for rectal cancer [0.03%]
细胞外黏蛋白池和中性粒细胞与淋巴细胞比率：揭开放化疗后直肠癌病理完全缓解的隐藏侵袭性特征
Zhenyu Xu,Heyuan Zhu,Xiaojie Wang et al.
Zhenyu Xu et al.
Background: Pathological complete response (pCR) following neoadjuvant chemoradiotherapy (nCRT) for locally advanced rectal cancer (LARC) does not eliminate tumor recurrence risk, with distant metastasis remaining a criti...
Apocrine carcinoma of the breast: distinctive metabolic reprogramming and high-frequency PIK3CA mutations revealed by molecular and immunohistochemical analysis [0.03%]
分子和免疫组化分析揭示的乳腺顶小叶癌特有的代谢重组及高频PIK3CA突变
Harumi Nakamura,Yoji Kukita,Nobuyoshi Kittaka et al.
Harumi Nakamura et al.
Aims: Apocrine carcinoma (AC) is a rare and distinct subtype of invasive breast carcinoma, typically characterized by androgen receptor (AR) positivity and negative expression of oestrogen and progesterone receptors. This...
Testicular mass frozen section examination: Pathological insights and diagnostic accuracy [0.03%]
睾丸肿物冷冻切片检查：病理学见解和诊断准确性
Roselyne Choiniere,Willem P A Boellaard,Marij Dinkelman-Smit et al.
Roselyne Choiniere et al.
Background and objectives: Testicular frozen section examination on excisional biopsy (FSEB) is an underused pathological and surgical approach, considering the increasing number of small benign testicular lesions found o...
Novel NOTCH3 alteration expanding the molecular spectrum of pericytic tumours: report of two cases [0.03%]
NOTCH3新突变扩展周细胞肿瘤分子分型报告两例
Irena Antonia Ungureanu,Megane Le Quang,Rihab Azmani et al.
Irena Antonia Ungureanu et al.
Introduction: Myofibromas are part of the pericytic tumour family, which includes myopericytomas, glomus tumours and angioleiomyomas. While they typically display benign behaviour when arising in the skin and subcutaneous...