Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi-pathologist validation and a reader study [0.03%]
基于人工智能的更新悉尼系统胃黏膜活检病理评估和重复性研究：多病理医生验证和阅读者研究
Ho Heon Kim,Won Chan Jeong,Yuri Hwang et al.
Ho Heon Kim et al.
Aims: The Updated Sydney System is the most widely used framework for histological grading of gastritis, but complete grading in routine gastric biopsies is time-consuming and subject to interobserver variability. We deve...
Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous [0.03%]
肝内胆管癌内的异柠檬酸脱氢酶1突变状态同质性良好
Sharon Weidmann,Silvana Ebner,Aayushi Srivastava et al.
Sharon Weidmann et al.
Introduction: IDH1 mutations occur in approximately 10%-20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy. As routine molecular diagnostics are commonly base...
Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous [0.03%]
肝内胆管癌中IDH1突变状态的同质性
Sharon Weidmann,Silvana Ebner,Aayushi Srivastava et al.
Sharon Weidmann et al.
Introduction: IDH1 mutations occur in approximately 10%-20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy. As routine molecular diagnostics are commonly base...
Saba Shafi,Josephine K Dermawan
Saba Shafi
Molecular advances have expanded the spectrum of cutaneous soft tissue tumours, leading to the recognition of several recently described entities with distinct genetic drivers. This review outlines the defining histopathological, immunophen...
Hybrid grading systems improve progression risk stratification in non-invasive papillary urothelial carcinoma and support a histomorphological continuum of disease progression [0.03%]
混合评分系统可改善非侵袭性乳头状尿路上皮癌的进展风险分层并支持疾病进展情况的组织病理学连续性
Jane K Nguyen,Marcello P Toscano,Jianbo Li et al.
Jane K Nguyen et al.
Objective: Histological grading is a key predictor of progression in non-muscle-invasive bladder cancer (NMIBC). The WHO 1973 three-tier system is limited by heterogeneity within the G2 category, whereas the WHO 2004/2016...
Solitary cutaneous histiocytosis: when genomics defines subclassification [0.03%]
单发性皮肤朗格汉斯细胞组织细胞增生症：当基因组学定义亚分类时
Thomas Papathomas,Markus Andreassen,Lorant Farkas et al.
Thomas Papathomas et al.
Histological assessment of treatment effect in lymph node-positive breast cancer after neoadjuvant chemotherapy [0.03%]
新辅助化疗后淋巴结阳性乳腺癌治疗效果的组织学评估
Yihong Wang,Jess Hart,Mariana Canepa et al.
Yihong Wang et al.
Aims: Neoadjuvant chemotherapy (NACT) is becoming the standard of care for lymph node (LN)-positive breast cancers. Residual disease in the breast and LN serves as a critical prognostic indicator and guides adjuvant thera...
Histopathological stratification of primary aldosteronism using the CYP11B2 size ratio: first evaluation in clinical routine [0.03%]
利用CYP11B2大小比值对原发性醛固酮增多症进行组织病理学分层：首次在临床常规中的评估
Adam Stenman,Tim Nilsson,Henrik Falhammar et al.
Adam Stenman et al.
Background: In primary aldosteronism (PA), the HISTALDO framework classifies aldosterone-producing lesions as 'classical' (solitary nodule) or 'non-classical' (multinodular or diffuse) based on CYP11B2 immunohistochemistr...
Time-dependent histopathological remodelling of the appendix in patients with ulcerative colitis [0.03%]
溃疡性结肠炎患者阑尾的时间依赖性组织病理学重塑
Kurara Yamamoto,Takanori Nishiguchi,Keiko Abe et al.
Kurara Yamamoto et al.
Aims: To characterize the endoscopic features of periappendiceal lesions and histopathological features of appendiceal lesions in patients with conventional ulcerative colitis (UC), particularly in relation to disease dur...
Nosological reappraisal of primary cutaneous apocrine carcinoma based on a clinicopathological and genetic analysis of 30 cases [0.03%]
基于临床病理和遗传分析的30例病例对原发性皮肤大汗腺癌进行疾病分类再评价
Keisuke Goto,Yoji Kukita,Shuichi Ohe et al.
Keisuke Goto et al.
Aims: The nosology of primary cutaneous apocrine carcinoma remains controversial, as the term has often been used as a heterogeneous diagnostic category. The aim of this study was to clarify the clinicopathological and mo...