Development and validation of a supervised deep learning algorithm for automated whole-slide programmed death-ligand 1 tumour proportion score assessment in non-small cell lung cancer [0.03%]
用于自动评估非小细胞肺癌中整体滑片式程序性死亡配体1肿瘤比例分数的监督深度学习算法的开发及验证
Liesbeth M Hondelink,Melek Hüyük,Pieter E Postmus et al.
Liesbeth M Hondelink et al.
Aims: Immunohistochemical programmed death-ligand 1 (PD-L1) staining to predict responsiveness to immunotherapy in patients with advanced non-small cell lung cancer (NSCLC) has several drawbacks: a robust gold standard is...
The International Collaboration on Cancer Reporting (ICCR): a decade of progress towards global pathology standardisation and data interoperability [0.03%]
国际癌症报告协作组（ICCR）：向着全球病理标准化和数据兼容性迈进的十年
John R Srigley,Meagan Judge,Tim Helliwell et al.
John R Srigley et al.
Large cell calcifying Sertoli cell tumour: a contemporary multi-institutional case series highlighting the diagnostic utility of PRKAR1A immunohistochemistry [0.03%]
大型细胞钙化的Sertoli细胞肿瘤：当代多机构病例系列强调PRKAR1A免疫组织化学的诊断作用
William J Anderson,Jennifer B Gordetsky,Muhammad T Idrees et al.
William J Anderson et al.
Aims: Large cell calcifying Sertoli cell tumour (LCCSCT) is a rare testicular sex cord-stromal tumour that primarily affects young patients and is associated with Carney complex. We sought to characterise the clinicopatho...
Multicenter Study
Histopathology. 2022 Mar;80(4):677-685. DOI:10.1111/his.14599 2022
The Bowel Cancer Screening Programme Expert Board: an analysis of activity during 2017-2020 [0.03%]
肠癌筛查计划专家委员会：2017-2020年活动分析
Adrian C Bateman,Octavia R Kurn,Marco R Novelli et al.
Adrian C Bateman et al.
Aims: The inception of the National Health Service Bowel Cancer Screening Programme in England in 2006 highlighted the fact that the differential diagnosis between the presence of epithelial misplacement and adenocarcinom...
Yale Rosen
Yale Rosen
Although precursor lesions of pulmonary squamous carcinoma, adenocarcinoma and carcinoid tumour are well known and accepted entities, precursor lesions of pulmonary neuroendocrine carcinomas, i.e. small-cell lung carcinoma and large-cell ne...
Clinical, radiological and pathological features of idiopathic and secondary interstitial pneumonia with pleuroparenchymal fibroelastosis in patients undergoing lung transplantation [0.03%]
肺移植患者中特发性和继发性伴胸膜肺弹力纤维增生的间质性肺炎的临床，影像和病理特征
Naoya Ikegami,Naoki Nakajima,Akihiko Yoshizawa et al.
Naoya Ikegami et al.
Aims: Idiopathic pleuroparenchymal fibroelastosis (PPFE) is a rare type of idiopathic interstitial pneumonia, and pathological PPFE is also observed in patients with secondary interstitial pneumonia. This study aimed to e...
Well-differentiated lipomatous neoplasms with p53 alterations: a clinicopathological and molecular study of eight cases with features of atypical pleomorphic lipomatous tumour [0.03%]
具有p53改变的分化良好的类脂瘤样新生物：八例不典型多形性类脂瘤样肿瘤临床病理及分子研究
Phoebe M Hammer,Christian A Kunder,Brooke E Howitt et al.
Phoebe M Hammer et al.
Aims: Well-differentiated lipomatous neoplasms encompass a broad spectrum of benign and malignant tumours, many of which are characterised by recurrent genetic abnormalities. Although a key regulator of p53 signalling, MD...
A refined approach to the diagnosis of Burkitt lymphoma in a resource-poor setting [0.03%]
在资源匮乏的环境中对伯基特淋巴瘤进行诊断的改进方法
Kikkeri N Naresh,Stefano Lazzi,Raffaella Santi et al.
Kikkeri N Naresh et al.
SRY-box transcription factor 10 is a highly specific biomarker of basal-like breast cancer [0.03%]
SRY框转录因子10是基底样乳腺癌的高度特异性生物标志物
Kristina-Ana Klaric,Nazia Riaz,Karama Asleh et al.
Kristina-Ana Klaric et al.
Aims: Basal-like breast cancer is an aggressive molecular subtype associated with younger age and early relapse. Most cases lack expression of oestrogen receptor (ER), progesterone receptor, and human epidermal growth fac...
Pathology updates and diagnostic approaches to haemophagocytic lymphohistiocytosis [0.03%]
噬血细胞综合征的病理学进展及诊断方法
Alexander Kikuchi,Kunwar Singh,Eric Gars et al.
Alexander Kikuchi et al.
Haemophagocytic lymphohistiocytosis (HLH) is a complex, often under-recognised hyperinflammatory immune dysregulation syndrome arising in a diverse range of clinical scenarios and conditions. The accurate and timely diagnosis of HLH is cruc...