Parallel evolution of two distinct lymphoid proliferations in clonal haematopoiesis [0.03%]
克隆性造血中两种不同淋巴增殖的平行进化
Ayoma D Attygalle,Rachel Dobson,Pui Kwan Chak et al.
Ayoma D Attygalle et al.
Aims: Angioimmunoblastic T-cell lymphoma (AITL) is genetically characterized by TET2 and DNMT3A mutations occurring in haematopoietic progenitor cells, and late events (e.g. the RHOA-G17V mutation) associated with maligna...
Case Reports
Histopathology. 2022 Apr;80(5):847-858. DOI:10.1111/his.14619 2022
Head to head: should we adopt the term 'sessile serrated lesion'? [0.03%]
面对面:我们是否应该采用“平型锯齿状病变”这一术语?
Iris D Nagtegaal,Dale C Snover
Iris D Nagtegaal
The precursor lesion for the ~30% of colon carcinomas developing along the serrated pathway was first described in detail in 1996, and was named sessile serrated adenoma in 2003. Although the entity itself was controversial initially, over ...
Incidence, clinicopathological features and genetics of in-situ follicular neoplasia: a comprehensive screening study in a Japanese cohort [0.03%]
日本人群体中就地滤泡性肿瘤的发病率、临床病理特征和遗传学:一项全面筛查研究
Naoki Oishi,Takahiro Segawa,Kunio Miyake et al.
Naoki Oishi et al.
Aims: In-situ follicular neoplasia (ISFN) is a histologically recognizable neoplastic proliferation of follicular lymphoma (FL)-like B cells confined to the germinal centres. While some ISFNs are associated with overt FL,...
Ovarian microcystic stromal tumour: from morphological observations to syndromic associations [0.03%]
卵巢微囊性间质瘤:从形态学观察到综合征关联
Carlos Parra-Herran,W Glenn McCluggage
Carlos Parra-Herran
Microcystic stromal tumour (MST) is a rare, usually benign, ovarian neoplasm characterized morphologically in its classic form by a distinctive triad of features comprising microcysts, solid cellular regions and fibrous stroma. Variant morp...
Key changes to the World Health Organization (WHO) classification of female genital tumours introduced in the 5th edition (2020) [0.03%]
《世界卫生组织女性生殖器官肿瘤分类》第5版(2020年)的主要修改点
W Glenn McCluggage,Naveena Singh,C Blake Gilks
W Glenn McCluggage
An updated World Health Organization (WHO) classification of female genital tumours was published in autumn 2020. We discuss the major new additions to and changes from the prior 2014 classification with a discussion of the reasons underlyi...
Daniel M Berney
Daniel M Berney
Aleodor A Andea
Aleodor A Andea
The work-up of melanocytic tumors has undergone significant changes in the last years following the exponential growth of molecular assays. For the practicing pathologist it is often difficult to sort through the myriad of different tests a...
'I Can't Keep Up!': an update on advances in soft tissue pathology occurring after the publication of the 2020 World Health Organization classification of soft tissue and bone tumours [0.03%]
软组织和骨肿瘤2020年世界卫生组织分类出版后软组织病理学进展概述:“我跟不上了!”
Andrew L Folpe
Andrew L Folpe
Progress in our understanding of the pathogenesis and diagnosis of soft tissue neoplasia is exceptionally rapid. Although the most recent World Health Organization classification of soft tissue tumours contains many new entities and refinem...
Dianne Torrence,Cristina R Antonescu
Dianne Torrence
Recent molecular advances have shed significant light on the classification of vascular tumours. Except for haemangiomas, vascular lesions remain difficult to diagnose, owing to their rarity and overlapping clinical, radiographic and histol...
Francois Le Loarer,Jessica Baud,Rihab Azmani et al.
Francois Le Loarer et al.
Round cell sarcomas represent a diagnostic challenge for pathologists, owing to the poorly differentiated features of these high-grade tumours. The diagnosis of round cell sarcoma requires large immunohistochemical panels and molecular test...