Reconsidering clinical translation of margin clearance and ablation in Barrett's-related endoscopic mucosal resection [0.03%]
从临床转化角度再思考巴雷特相关内镜下黏膜切除术的切缘阴性及消融完全的概念
Qiang Wu,Li Wang,Feiying Gao et al.
Qiang Wu et al.
Papillary renal cell carcinoma, formerly known as Type 2: a single institutional study addressing histologic and molecular features [0.03%]
乳头状肾细胞癌（曾称为2型）的组织学和分子特征研究
Melissa Yuwono Tjota,Jung Woo Kwon,Pankhuri Wanjari et al.
Melissa Yuwono Tjota et al.
Aims: Papillary renal cell carcinoma (pRCC) accounts for 15%-20% of RCC cases and is the second most common histologic subtype of RCC. In contrast to other common RCC subtypes, there continues to be ongoing debate about h...
Apocrine encapsulated papillary carcinoma: a comprehensive clinicopathological analysis of 28 cases [0.03%]
顶泌型囊内乳头状癌的临床病理特征（28例报告）
Ke Zuo,Ruohong Shui,Xiaoli Xu et al.
Ke Zuo et al.
Aims: Encapsulated papillary carcinoma (EPC) is characterized by neoplastic epithelial cells of low-to-intermediate nuclear grade arranged along fibrovascular cores. Classical EPC typically expresses oestrogen receptor (E...
Next-generation sequencing-based IG clonality analysis to discriminate reactive infiltrates from minimal lymphoma involvement in paired lymphoma and bone marrow biopsies; a EuroClonality-NGS Working Group study [0.03%]
基于下一代测序的免疫球蛋白克隆性分析，以鉴别淋巴瘤和骨髓活检配对样本中的反应性浸润和微量淋巴瘤病灶：EuroClonality-NGS工作组研究
Michiel van den Brand,Meilinde Leenders,Jos Rijntjes et al.
Michiel van den Brand et al.
Aims: Bone marrow (BM) biopsy is an important procedure in B-cell lymphoma staging. In most biopsies, the presence or absence of a lymphoma infiltrate can reliably be determined by standard histology. However, in a subset...
Ovarian Sertoli-Leydig cell tumors with heterologous rhabdomyosarcoma: Clinicopathologic features and molecular analysis highlighting recurrent genetic alterations [0.03%]
具有异源性横纹肌肉瘤的卵巢塞利希-莱迪奇细胞肿瘤的临床病理特征及分子分析高亮反复出现的遗传改变
Ying S Zou,Sanobar Yasmeen Mohammed,Jing Zhu et al.
Ying S Zou et al.
Aims: Ovarian Sertoli-Leydig cell tumor (SLCT) with heterologous rhabdomyosarcoma (RMS) is exceptionally rare. While the presence of heterologous elements in SLCT is highly predictive of an underlying DICER1 mutation, the...
Tatiana S Driva,Stratigoula Sakellariou,Irene Theochari et al.
Tatiana S Driva et al.
Aims: Metaplastic alterations of oxyntic mucosa in autoimmune gastritis (AIG) remain under investigation. This study aimed to characterize pyloric gland-like and intestinal metaplasia (IM) in AIG and assess their origin a...
Prostate cancer molecular subtypes in systematic versus MRI-targeted biopsy cores at active surveillance: association of PTEN and ERG status with extreme grade reclassification [0.03%]
系统活检与MRI目标活检在主动监测前列腺癌分子亚型中的差异：PTEN和ERG状态与极端分级重分类的关系
Claire M de la Calle,Oluwademilade O Dairo,Zhuo Tony Su et al.
Claire M de la Calle et al.
Aims: Biomarkers are needed to identify patients with favourable-risk prostate cancers who could benefit from treatment versus active surveillance (AS). MRI-targeted biopsies may allow for better sampling of the 'dominant...
Tiffany Liv,Antoine Touzé,David Schrama et al.
Tiffany Liv et al.
RB1 was the first identified tumour suppressor gene, named for its crucial role in opposing retinoblastoma oncogenesis. The RB1 gene encodes the retinoblastoma protein pRB, which is a well-known negative regulator of the cell cycle. However...
Diagnosing oncocytic renal tumours on renal mass biopsy; pathological concordance and the impact of evolving classification [0.03%]
肾肿瘤活检中的滤泡性肾肿瘤诊断；病理一致性及分类发展的影响
Shifaa&#x; Al Qa&#x;qa&#x;,Carol C Cheung,Satheesh Krishna et al.
Shifaa&#x; Al Qa&#x;qa&#x; et al.
Aims: Renal tumours with oncocytic morphology are among the most difficult to classify at renal mass biopsy (RMB), and a number of emerging entities with low-grade oncocytic morphology have been recently described. This s...
Interobserver variability of histopathological assessment in pT1 colorectal carcinoma [0.03%]
pT1期结直肠癌病理评估的观察者间变异度研究
Karmele Saez de Gordoa,María Daca-Alvarez,Maite Rodrigo-Calvo et al.
Karmele Saez de Gordoa et al.
Aims: Pathological evaluation of colorectal carcinoma (CRC) diagnosed at stage pT1 is challenging. Nevertheless, it is crucial for treatment guiding and to determine the patient's prognosis. This study aimed to assess the...