A minor high-grade component in non-invasive papillary urothelial carcinoma is not associated with a more indolent behaviour [0.03%]
非侵袭性乳头状尿路上皮癌中的低级别成分并不预示着更良性的行为特征
Mina S Farag,Neda Oghbaei,Jaffar Hussain et al.
Mina S Farag et al.
Aims: The latest WHO edition proposed using a cut-off of ≥5% high-grade component (%HGc) as a criterion to label non-invasive papillary urothelial carcinomas as high-grade (pTaHG). It also suggested that tumours with min...
Correct diagnosis of patients with fibrolamellar carcinoma: A Dutch nationwide study [0.03%]
荷兰全国范围内纤维板层肝癌患者正确诊断的研究
Alicia Furumaya,Abisha Gumede,Víola B Weeda et al.
Alicia Furumaya et al.
Aims: Fibrolamellar carcinoma (FLC) is a rare primary liver cancer. Adequate diagnosis is essential for appropriate treatment. The current study evaluates the diagnosis of fibrolamellar carcinoma in a Dutch cohort. ...
Human papilloma virus infection and mismatch repair protein expression in sebaceous neoplasms of the genital area [0.03%]
外阴皮脂腺肿瘤中人乳头瘤病毒感染和错配修复蛋白表达的关系研究
Katharina Wiedemeyer,Zainab Al-Shamma,Martin Köbel et al.
Katharina Wiedemeyer et al.
Aims: This study aimed to investigate the clinical and histopathological features of sebaceous tumours of the genital area and their association with human papilloma virus (HPV) infection and mismatch repair (MMR) protein...
Tall cell carcinoma with reversed polarity of the breast harbouring IDH1 hotspot mutation: morphologic, immunohistochemical and genetic characterization of two cases [0.03%]
形态学、免疫组化和遗传表型特征的2例IDH1热点突变伴极向逆转的高细胞癌病例报告
Gregor Krings,Sherin Hashem,Marsha A Apushkin et al.
Gregor Krings et al.
Aims: Tall cell carcinomas with reversed polarity (TCCRPs) are rare, indolent triple negative or oestrogen receptor (ER)-low positive breast cancers classically characterized by solid-papillary and papillary proliferation...
Tumour budding in pretreatment cervical biopsies: a prognosticator for personalised therapy in the era of precision oncology [0.03%]
精准肿瘤学时代个性化治疗的预后指标：术前宫颈活检中的肿瘤芽生现象
Young Sub Lee,Kwangil Yim,Chan Joo Kim et al.
Young Sub Lee et al.
Aims: Tumour budding (TB) is a noteworthy morphologic indicator for tumour microenvironment (TME) especially because it is detectable with routine haematoxylin and eosin (H&E) staining. Its prognostic relevance has been d...
GREB1-rearranged uterine tumour shares a common DNA methylation signature with ESR1-rearranged UTROSCT [0.03%]
GREB1重组型子宫肿瘤与ESR1重组型UTROSCT具有共同的DNA甲基化特征
Cheng-Han Lee,Yow-Shan Lee,Jennifer A Bennett et al.
Cheng-Han Lee et al.
Background and objectives: GREB1-rearranged uterine tumours encompass a group of uterine mesenchymal tumours with varied histologic appearances. The fusion partners to GREB1 include NCOA1-3, SS18 and NR4A3. Given that som...
Claudin-18 expression in gastric type adenocarcinoma and HPV-associated adenocarcinoma of the uterine cervix [0.03%]
Claudin-18在胃型腺癌和HPV相关宫颈腺癌中的表达
Nobuko Yasutake,Yuki Yokawa,Takehiro Tanaka et al.
Nobuko Yasutake et al.
Aims: Claudin-18 (CLDN18) is both a marker for the gastric phenotype and a therapeutic target. However, little is known about its immunoexpression in endocervical adenocarcinomas (ECAs), particularly as detected using the...
Mucinous metaplasia in a mixed epithelial and stromal tumour of the seminal vesicle: a potential precursor to mucinous adenocarcinoma [0.03%]
精囊混合上皮和间质瘤的粘液样异位增生：可能的粘液腺癌前体病变
Nathnael Tezera Tuffa,Emma Sheldon,Pedro Oliveira
Nathnael Tezera Tuffa
Well-differentiated papillary mesothelial tumour: histologic, molecular and genetic features support a benign clonal neoplasm despite diffuse peritoneal involvement [0.03%]
分化良好的乳头状间皮肿瘤：组织学、分子和遗传特征支持一种良性克隆新生物，尽管存在广泛的腹膜受累
Charles Leduc,Kurosh Rahimi,Frédéric Mercier et al.
Charles Leduc et al.
The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges [0.03%]
原位乳头状乳腺癌伴浸润和浸润性乳腺癌伴乳头状特征的谱系：组织学亚型及诊断难点概述
Emad A Rakha,Puay Hoon Tan,Wendy A Raymond
Emad A Rakha
Invasive breast carcinomas with papillary features (IBCP) constitute a distinct and morphologically diverse group of breast cancers characterised by varying degrees of papillary architecture and invasive behaviour. IBCP encompass (1) papill...