Bronchiolar adenoma and glandular papilloma/mixed squamous cell and glandular papilloma represent a continuous disease spectrum: revelations from combined histological and genetic analysis [0.03%]
支气管腺瘤和腺样乳头状瘤/鳞状细胞与腺样乳头状瘤混合型代表连续的疾病谱系：结合组织学和遗传分析的结果
Zhenghua Piao,Jiayun Xu,Lu Li et al.
Zhenghua Piao et al.
Aims: Despite their common bronchial/bronchiolar origin, the relationship between glandular/mixed papillomas (GPs/MPs) and bronchiolar adenomas (BAs) remains uncertain; therefore, this study aimed to elucidate it. ...
Traditional serrated adenoma of the colorectum: Evolving concepts in histological classification and terminology [0.03%]
传统锯齿状腺瘤的分类及术语变迁——结直肠传统锯齿状腺瘤的病理学研究进展
Christophe Rosty,Maurice B Loughrey,Taiki Hashimoto et al.
Christophe Rosty et al.
Traditional serrated adenoma (TSA) is the least common of the currently recognized serrated colorectal polyps and, thus, elucidating its pathogenesis, spectrum of morphological features and biological risk has been challenging. Most TSAs ha...
Low-risk HPV-associated invasive carcinoma with squamous and glandular features arising in a Buschke-Löwenstein tumour [0.03%]
Buschke-Lowenstein瘤中发生低危HPV相关同时具有鳞状和腺细胞特征的浸润性癌
Nuray Tezcan,Jinru Shia,Dorukhan Bahceci
Nuray Tezcan
Aims: Low-risk human papillomavirus (LR-HPV) types 6 and 11 are classically associated with benign anogenital condylomas and are only rarely implicated in malignant transformation. Reported carcinomas associated with LR-H...
Perineurioma-like EMA-positive calvarial neoplasms: clinicopathological study of eight cases [0.03%]
类似颗粒细胞瘤且EMA阳性的颅骨肿瘤：8例临床病理研究
Raheel Rizwan,Yingting Mok,Josephine K Dermawan et al.
Raheel Rizwan et al.
Background: Incidental skull lesions are increasingly detected due to the widespread use of brain imaging. We have encountered an unusual cohort of unclassifiable calvarial spindle cell lesions showing phenotypic overlap ...
Intramuscular myxoma with chondroid features: two cases expanding the morphological spectrum [0.03%]
具有软骨特征的肌内黏液瘤两例报告：扩展形态谱系
Bethany Batson,Azfar Neyaz,Lucas Da Gama Lobo et al.
Bethany Batson et al.
Background: Intramuscular myxoma is a benign mesenchymal tumour typically composed of bland spindle to stellate cells in abundant myxoid stroma and usually characterized by GNAS mutations. Chondroid matrix has not been pr...
Updates and controversies in contemporary grading of clear cell renal cell carcinoma and papillary renal cell carcinoma [0.03%]
当前透明细胞肾细胞癌和乳头状肾细胞癌分级的更新与争议
Gladell P Paner,Mahul B Amin,Jung Woo Kwon et al.
Gladell P Paner et al.
A decade into the formal adoption of the World Health Organization (WHO)/International Society of Urological Pathology (ISUP) grading system for clear cell renal cell carcinoma (CCRCC) and papillary renal cell carcinoma (PRCC), newer gradin...
Unveiling the molecular profile of adenosquamous gallbladder carcinoma: characterization of a Caucasian cohort [0.03%]
揭开胆囊腺鳞癌分子特征的面纱：对高加索人队列的表征研究
Jessica Gasparello,Valentina Angerilli,Mario Domenico Rizzato et al.
Jessica Gasparello et al.
Aims: Gallbladder carcinoma (GBC) is a rare and highly aggressive malignancy associated with poor clinical outcomes. While most GBCs are adenocarcinomas, only a small subset shows squamous differentiation. Tumours contain...
Extra-appendiceal low-grade mucinous neoplasm-like lesions: clinicopathologic and molecular characteristics [0.03%]
额外-appendix低级别黏液性肿瘤样病变：临床病理和分子特征
Soo Hyun Lee,Berk Kaan Aktas,Avery Kim et al.
Soo Hyun Lee et al.
Aims: We identified three extra-appendiceal low-grade appendiceal mucinous neoplasms (LAMN)-like lesions occurring in the absence of appendiceal involvement, raising uncertainty regarding their classification, biologic na...
Yasamin Mirzabeigi,Amr Abulaban,Hisham F Bahmad et al.
Yasamin Mirzabeigi et al.
Aims: Uterine smooth muscle tumours (SMTs) conventionally express myogenic markers such as desmin, h-caldesmon and smooth muscle actin by immunohistochemistry. In contrast, the frequency and extent of melanocytic marker (...
Borderline breast lesions and the limits of classification: insights from the UK National Breast Screening EQA scheme [0.03%]
乳腺边缘病变的分类限度：英国全国乳腺筛查EQAS计划的启示
Emad A Rakha,Elena Provenzano,Angela Kingham et al.
Emad A Rakha et al.
Background: Previous concordance studies in breast pathology have demonstrated high levels of diagnostic agreement. This study aimed to characterize breast lesions associated with the lowest levels of concordance within t...