Pathological assessment of tumour beds in breast excisions post-neoadjuvant therapy: a retrospective cohort study [0.03%]
新辅助治疗后乳腺切除标本的病理评估：一项回顾性队列研究
Angela Cheng,Penelope Barnes,Daniel Rayson et al.
Angela Cheng et al.
Aims: The pathological assessment of breast cancer resection specimens with neoadjuvant therapy (NAT) offers invaluable information for prognosis and further management. At times, these cases are difficult to pathological...
Diagnostic utility of inflammatory markers in formalin-fixed and paraffin-embedded muscle biopsies for idiopathic inflammatory myopathies [0.03%]
石蜡包埋肌肉组织切片中炎症标志物的诊断价值研究:idopathic炎症性肌病患者的肌肉活检指标分析
Chinnawut Suriyonplengsaeng,Jariya Waisayarat
Chinnawut Suriyonplengsaeng
Objective: This study aimed to develop a reproducible immunohistochemistry method for formalin-fixed, paraffin-embedded (FFPE) muscle sections and to assess its diagnostic utility for idiopathic inflammatory myopathies (I...
Consistency of c-Met protein overexpression over time in patients with non-squamous non-small cell lung cancer [0.03%]
非鳞状非小细胞肺癌患者中c-Met蛋白过度表达的随时间变化的一致性研究
Alexis B Cortot,Romain Dubois,Valérie Grégoire et al.
Alexis B Cortot et al.
Aims: The c-Met signalling pathway is dysregulated in non-small cell lung cancer (NSCLC), with c-Met protein overexpression emerging as a potentially actionable biomarker given the development of c-Met-targeted antibody-d...
Secretory carcinoma of the breast: a report of six cases with different immunophenotypes and molecular subtypes [0.03%]
分泌性乳腺癌六例并有不同的免疫表型和分子亚型报告
María Ángeles López-García,Lourdes Galán,Blas Meléndez et al.
María Ángeles López-García et al.
Aim: Secretory carcinoma is a rare and well-recognized subtype of breast carcinoma generally associated with a favourable prognosis. Although it was initially described in young patients, it is now known to occur at any a...
NFE2L2-mutated urothelial carcinomas frequently show concomitant myxoid and squamous features and have high PD-L1 expression [0.03%]
NFE2L2突变的尿路上皮癌常表现为并发黏液样和鳞状特征并高表达PD-L1
Dane Wuori,Alexander Guzzetta,Melissa Y Tjota et al.
Dane Wuori et al.
Aims: NFE2L2 encodes the transcription factor, NRF2, which is a regulator of cellular oxidative stress responses and metabolic homeostasis. NFE2L2 alterations are implicated in multiple cancers, with significant study in ...
The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist [0.03%]
2025年ATS/ERS间质性肺炎国际多学科分类更新：对病理学家的影响
Andrew G Nicholson,Wendy A Cooper,Aurelie Fabre et al.
Andrew G Nicholson et al.
A consensus classification for idiopathic interstitial pneumonias was first published in 2002, providing terminology for clinicians, radiologists and pathologists as well as highlighting that a multidisciplinary approach was best clinical p...
Landscape of genetic alterations affecting cancer genes in primary and advanced malignant phyllodes tumours [0.03%]
原发和晚期恶性叶状肿瘤影响癌症基因的遗传改变景观
Selma Yeni Yildirim,Pier Selenica,Andrea Gazzo et al.
Selma Yeni Yildirim et al.
Background: Malignant phyllodes tumours (MPT) are aggressive breast fibroepithelial neoplasms. Their rarity has limited their genetic characterization, and associations with genetic ancestry and progression drivers remain...
Spatial transcriptomics reveals clonal relationships between intraductal carcinoma and adjacent invasive prostate cancer [0.03%]
空间转录组学揭示了导管内癌及其邻近侵袭性前列腺癌之间的克隆关系
Hridya Harikumar,Myrthe de Waard-van Baardwijk,Marit de Haan et al.
Hridya Harikumar et al.
Aims: The pathogenesis of intraductal carcinoma (IDC) is still controversial. Contrary to current opinion, where IDC represents retrograde spread of invasive prostate cancer (PCa), we recently presented an alternative, un...
Breast core needle biopsy diagnosis and personalized treatment: navigating pitfalls and challenging lesions [0.03%]
乳腺核心针活检诊断及个性化治疗：规避陷阱和应对疑难病变
Emad A Rakha,Cecily Quinn,Puay Hoon Tan et al.
Emad A Rakha et al.
Most breast lesions can be diagnosed accurately on core needle biopsy (CNB); however, certain entities remain diagnostically challenging due to limited tissue sampling, morphological overlap with other lesions, unusual immunoprofiles or lac...