Pedram Argani
Pedram Argani
The MiT subfamily of transcription factors includes TFE3, TFEB, TFEC and MITF. Gene fusions involving two of these transcription factors have been well characterized in two subtypes of renal cell carcinoma (RCC): TFE3-rearranged RCC (also k...
Lori A Erickson,Sounak Gupta,Rumeal D Whaley
Lori A Erickson
Changes in the nomenclature and classification of adrenal gland diseases are the result of advances in understanding the pathogenesis, germline susceptibility and the clonal-neoplastic nature of diseases of the adrenal gland. Although numer...
Liang Cheng,Daniel M Berney
Liang Cheng
Editorial
Histopathology. 2026 Jan;88(1):3-7. DOI:10.1111/his.70060 2026
Second edition ICCR dataset for testicular germ cell tumours: a reporting guide for histopathological diagnosis of orchiectomy specimens [0.03%]
睾丸生殖细胞肿瘤的ICCR第二版数据集：对睾丸切除标本的病理诊断报告指南
Felix Bremmer,Fleur Webster,Gedske Daugaard et al.
Felix Bremmer et al.
To summarise the content and significance of the recently published second edition International Collaboration on Cancer Reporting (ICCR) histopathology dataset for testicular germ cell tumours, covering the Orchiectomy specimen dataset. We...
Grading of bladder cancer: updates, controversies and practical solutions [0.03%]
膀胱癌分级：更新、争议及实用解决方案
Michelle R Downes,Theodorus H van der Kwast,Antonio Lopez-Beltran et al.
Michelle R Downes et al.
Bladder cancer grading provides important prognostic information to clinicians, and the assigned grade is used as a variable in risk stratification models. There have been multiple proposed grading schemes over the last century, with the mo...
Advances in non-germ cell tumours of the testis: focus on new molecular developments in sex cord-stromal tumours [0.03%]
睾丸非生精细胞肿瘤的进展：聚焦性索-间质瘤的新分子发展要点
João Lobo,Andres M Acosta
João Lobo
Testicular sex cord-stromal tumours (TSCSTs) represent ~4%-8% of all testicular neoplasms. Most show a Leydig or Sertoli cell phenotype and exhibit benign clinical behaviour. However, a subset of ~10% is malignant and clinically problematic...
Molecular pathology of testicular germ cell tumours: an update for practicing pathologists [0.03%]
睾丸生殖细胞肿瘤的分子病理学：实用病理工作者的更新版
Alexander Fichtner,Stefanie Zschäbitz,Daniel Nettersheim et al.
Alexander Fichtner et al.
Testicular tumours are a diverse group of tumours, but most cases fall into the category of testicular germ cell tumours (TGCT). TGCTs are classified as either derived from a germ cell neoplasia in situ (GCNIS) or unrelated to GCNIS. Based ...
The Paris system for reporting urinary cytology: what worked and what still needs to be improved [0.03%]
巴黎泌尿系统细胞学报告体系的优缺点
Eva M Wojcik
Eva M Wojcik
Urine cytology has long been a challenging diagnostic modality due to its low sensitivity for low-grade urothelial neoplasms and high interobserver variability. The introduction of The Paris System (TPS) in 2016 marked a pivotal shift towar...
Ankush U Patel,Anil V Parwani,Swati Satturwar
Ankush U Patel
Artificial intelligence (AI) is now a practical, value-generating tool in genitourinary (GU) pathology. Real-world deployments report up to 65% time-savings and multi-million-dollar returns on investment within 3 years at high-volume centre...
Dilara Akbulut,Hikmat Al-Ahmadie
Dilara Akbulut
Small cell carcinoma is the most frequently encountered neuroendocrine tumour (NET) of the urinary bladder, and it may present as either pure or in combination with urothelial carcinoma or other histological subtypes. Large cell neuroendocr...