Tiffany Liv,Antoine Touzé,David Schrama et al.
Tiffany Liv et al.
RB1 was the first identified tumour suppressor gene, named for its crucial role in opposing retinoblastoma oncogenesis. The RB1 gene encodes the retinoblastoma protein pRB, which is a well-known negative regulator of the cell cycle. However...
Diagnosing oncocytic renal tumours on renal mass biopsy; pathological concordance and the impact of evolving classification [0.03%]
肾肿瘤活检中的滤泡性肾肿瘤诊断；病理一致性及分类发展的影响
Shifaa&#x; Al Qa&#x;qa&#x;,Carol C Cheung,Satheesh Krishna et al.
Shifaa&#x; Al Qa&#x;qa&#x; et al.
Aims: Renal tumours with oncocytic morphology are among the most difficult to classify at renal mass biopsy (RMB), and a number of emerging entities with low-grade oncocytic morphology have been recently described. This s...
Interobserver variability of histopathological assessment in pT1 colorectal carcinoma [0.03%]
pT1期结直肠癌病理评估的观察者间变异度研究
Karmele Saez de Gordoa,María Daca-Alvarez,Maite Rodrigo-Calvo et al.
Karmele Saez de Gordoa et al.
Aims: Pathological evaluation of colorectal carcinoma (CRC) diagnosed at stage pT1 is challenging. Nevertheless, it is crucial for treatment guiding and to determine the patient's prognosis. This study aimed to assess the...
Diagnostic potential of a novel immunohistochemical marker, GFPT2, in differentiating mesothelioma from its morphological mimics [0.03%]
新型免疫组化标记物GFPT2在区分间皮瘤及其形态类似病变中的诊断价值研究
Jia Wei,Xiaofang Ma,Gang Chen et al.
Jia Wei et al.
Aims: Mesothelioma (MESO) is a rare and aggressive tumour originating from mesothelial cells, primarily affecting the pleura and peritoneum. Its diagnosis remains challenging due to non-specific clinical, radiological and...
Immunohistochemical characterization of peritoneal inclusion cysts with squamous metaplasia [0.03%]
具有鳞状上皮化的腹膜包裹囊肿的免疫组化表型特征分析
Heather I Chen-Yost,David B Chapel,Steven M Hrycaj et al.
Heather I Chen-Yost et al.
Aims: Peritoneal inclusion cysts (PICs) are mesothelial-lined cysts that can uncommonly develop squamous metaplasia. Here, we describe the immunophenotype of PICs with squamous metaplasia using a comprehensive immunohisto...
Roger Feakins
Roger Feakins
Editorial
Histopathology. 2026 Jan;88(2):379. DOI:10.1111/his.70059 2026
Pathological features, differential diagnosis, prognosis, and diagnostic challenges in the classification of penile squamous neoplasia [0.03%]
阴茎鳞状细胞肿瘤的病理特征、鉴别诊断、预后及分类中的诊断挑战
Ingrid Rodriguez,Maria Jose Fernandez-Nestosa,Diego Sanchez et al.
Ingrid Rodriguez et al.
Approximately 50% of penile squamous cell carcinomas are of the usual (conventional) type, resembling their counterparts in the skin or other organs. The remaining half comprises a heterogeneous group of histological variants, some of which...
Recent developments in eosinophilic renal neoplasms: what's new, true and important? [0.03%]
近年关于嗜酸细胞肾肿瘤的研究进展：哪些是新的、重要的和可信的？
Kiril Trpkov,Farshid Siadat,Rola Saleeb
Kiril Trpkov
We focus in this review on the latest developments on several eosinophilic renal entities, aiming to provide an update on this topic that was previously addressed by the Genitourinary Pathology Society in their consensus papers on existing ...
Treatment-related changes in the prostate: past, present and future therapies [0.03%]
前列腺治疗引起的改变：过去、现在和未来的疗法
Katrina Collins,Liang Cheng
Katrina Collins
A broad spectrum of therapies is available for the management of prostate cancer, ranging from well-established interventions like radical prostatectomy, androgen deprivation therapy (ADT) and radiation therapy (RT), to emerging modalities ...
Antonio Lopez-Beltran,Ana Blanca,Michelle R Downes et al.
Antonio Lopez-Beltran et al.
Significant progress has been achieved in elucidating the molecular underpinnings of bladder cancer initiation and progression. Translational research has identified mutations in chromatin-modifying genes such as KMT2D and KDM6A, which faci...