Flat epithelial atypia of the breast: a pragmatic, context-integrated diagnostic framework within a biological continuum [0.03%]
乳腺扁平上皮非典型病变：一种实用的、基于背景情况的诊断标准及其在生物学连续谱中的定位框架
Emad A Rakha
Emad A Rakha
Flat epithelial atypia (FEA) is a diagnostically challenging lesion within the spectrum of columnar cell alterations of the breast, occupying a borderline position between benign columnar cell change and flat type intermediate nuclear grade...
Nicolas Macagno,Diane Frankel,Alexandra Meurgey et al.
Nicolas Macagno et al.
Aims: Myxomas are benign soft tissue neoplasms typically driven by activating GNAS mutations. However, a subset lacks this alteration and remains molecularly undefined. Recent reports have implicated MAP3K family gene fus...
TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma [0.03%]
肺大细胞神经内分泌癌中TROP2的表达分布及临床意义
Michael Minkley,Kashif Ravasia,Thi Nghiem et al.
Michael Minkley et al.
Introduction: TROP2 antibody-drug conjugates have shown promising anti-tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma ...
Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges [0.03%]
乳腺恶性腺肌上皮瘤七例临床病理报道及诊断陷阱分析
Sompon Apornvirat,Edward Jaya Hadi,Mihir Gudi et al.
Sompon Apornvirat et al.
Background: Malignant adenomyoepithelioma (M-AME) is an extremely rare and morphologically diverse breast tumour, posing significant diagnostic and management challenges. We present seven cases of M-AME with different his...
A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile [0.03%]
一例CRX阳性RB1缺陷型骨肿瘤伴有视网膜母细胞瘤样的DNA甲基化谱型
Akifumi Nozawa,Daichi Hayashi,Shiho Yasue et al.
Akifumi Nozawa et al.
Perivascular epithelioid cell tumours of the genitourinary tract: clinicopathological features and molecular landscape [0.03%]
泌尿生殖道血管周上皮样细胞肿瘤的临床病理特征和分子图谱分析
Busra Yaprak Bayrak,Mahmut Akgul,Michael Cheng et al.
Busra Yaprak Bayrak et al.
Perivascular epithelioid cell tumours (PEComas) comprise a distinctive and biologically heterogeneous family of mesenchymal neoplasms defined by perivascular epithelioid differentiation and dual melanocytic and smooth muscle-like immunophen...
Navigating diagnostic challenges in low-grade spindle cell lesions of the breast: a retrospective review [0.03%]
低级别乳腺梭形细胞病变的诊断挑战及回顾性分析
Graham Stoddard,Rabeka Ali,Ozlen Saglam
Graham Stoddard
Aims: Low-grade spindle cell lesions of the breast (LGSCL-B) are uncommon, with malignant counterparts being particularly rare. Management recommendations for desmoid-type fibromatosis (DF), in particular, have evolved. ...
Neoplastic transformation of sporadic gastric hyperplastic polyps: a systematic review and meta-analysis of risk factors and clinicopathological features [0.03%]
胃息肉癌变的系统评价和 Meta 分析：危险因素及临床病理特征分析
Inês Maria Ferreira,Mariana Simplício,Rafael José Vieira et al.
Inês Maria Ferreira et al.
This systematic review with meta-analysis aims to analyse the existing literature on clinicopathological features of sporadic gastric hyperplastic polyps (GHP), with special emphasis on risk factors associated with neoplastic transformation...
KRAS-mutant serrated lesion with TSA-like dysplasia in the appendix [0.03%]
带有TSA样不典型增生的结肠型锯齿状腺瘤并kras突变appendiceal KRAS-mutant serrated lesion with tumor-specific adenoma like dysplasia
Hanna Henzinger,Cord Langner
Hanna Henzinger
Primary pseudomyogenic haemangioendothelioma of the lung with a novel ACTG1::FOSB gene fusion [0.03%]
新型ACTG1::FOSB基因融合的原发性肺假肌源性血管内皮细胞瘤
Mengqin Xiang,Mengjun Mo,Feicheng Yang et al.
Mengqin Xiang et al.