Tumour-infiltrating lymphocytes, tertiary lymphoid structures and myxoid stroma predict upstaging of ductal carcinoma in situ in breast biopsies [0.03%]
肿瘤浸润性淋巴细胞、三级淋巴结构和黏液样间质可预测乳腺导管原位癌活检的期别加重
Chung-Yen Huang,Yu-Jui Wang,Min-Shu Hsieh et al.
Chung-Yen Huang et al.
Aims: We aimed to evaluate tumour-infiltrating lymphocytes (TILs), tertiary lymphoid structures (TLSs) and myxoid stroma in breast biopsies diagnosed with atypical ductal hyperplasia (ADH) and ductal carcinoma in situ (DC...
Gynaecological serous carcinomas exhibiting squamous differentiation: exploding a myth [0.03%]
具有鳞状分化妇科浆液性癌：破解一个传说
Lucy Hamer,Shatrughan Sah,W Glenn McCluggage
Lucy Hamer
S100 expression in molecularly confirmed dermatofibrosarcoma protuberans, including fibrosarcomatous variants [0.03%]
分子确诊的隆突性皮肤纤维肉瘤（包括肉瘤样变异型）中S100的表达
Azfar Neyaz,Dale Davis,David J Papke Jr et al.
Azfar Neyaz et al.
Aims: Dermatofibrosarcoma protuberans (DFSP) is a superficial, locally aggressive spindle cell neoplasm, characterised by diffuse CD34 expression and the presence of COL1A1::PDGFB or related fusions. S100 expression is no...
TRPS1 expression in neuroendocrine neoplasms of breast and other organs [0.03%]
神经内分泌肿瘤中的TRPS1表达研究——乳腺及其他器官肿瘤中的作用与机制
Qiqi Ye,Jeannelyn Estrella,Neda Kalhor et al.
Qiqi Ye et al.
Background: Primary neuroendocrine (NE) neoplasms of the breast are rare. In the absence of in situ carcinoma, metastasis from other organs needs to be ruled out first. TRPS1 is a recently identified marker for breast ori...
Clinicopathological and molecular characterization of seven rare cases of renal cell carcinoma with hemangioblastoma-like features: Expanding the morphological spectrum of renal tumours with tuberous sclerosis complex/mammalian target of rapamycin mutations [0.03%]
七例具有血管球芽细胞瘤样特征肾细胞癌的临床病理及分子特点分析：含结节硬化症/TSC-MTOR途径突变肿瘤形态谱系的扩展
Xuan Tao,Xiao-Tong Wang,Peng-Cheng Wang et al.
Xuan Tao et al.
Aims: Renal cell carcinoma with hemangioblastoma-like features (RCC-HB) is a rare renal cell carcinoma (RCC) subtype. It consists of renal cell carcinoma with fibromyomatous stroma (RCC FMS)-like and hemangioblastoma (HB)...
Low-grade glial neoplasms of germ cell origin may represent maturation of embryonic-type neuroectodermal elements [0.03%]
低度胶质瘤的生精细胞起源可能代表了胚胎型神经外胚叶成分的成熟化
João Lobo,Nuno Tiago Tavares,Fernanda Fernandes-Pontes et al.
João Lobo et al.
Aims: Glial tumours of germ cell origin are relatively rare in men, occurring predominantly after chemotherapy. Many exhibit low-grade histological features within a spectrum that includes teratomas with mature glial/gang...
Colorectal carcinoma with sarcomatoid component: isolated SMARCA2 loss and high PD-L1 expression as a potential therapeutic target [0.03%]
富含肉瘤样成分的结直肠癌中SMARCA2缺失和高PD-L1表达可能是一个潜在的治疗靶点
Furkan Aknar,Tuce Soylemez-Akkurt,Huseyin Karatay
Furkan Aknar
A 5-marker immunohistochemical panel of CK17, MEP1A, PAX8, SMAD4, and CDX2 to distinguish ovarian mucinous carcinoma from metastatic pancreatic ductal adenocarcinoma [0.03%]
CK17、MEP1A、PAX8、SMAD4和CDX2的5标记免疫组化谱鉴定卵巢黏液性癌与转移性胰腺导管腺癌
Astrid De Boeck,Eun Young Kang,Nicola S Meagher et al.
Astrid De Boeck et al.
Aims: Metastatic pancreatic adenocarcinoma (PDAC), albeit uncommon, may involve the ovary, and distinction from primary ovarian mucinous tumours (OMT) poses a diagnostic challenge. Our aim was to develop an ancillary immu...
Taishi Takahara,Natsuki Taniguchi,Naoto Sassa et al.
Taishi Takahara et al.
Aims: Intraductal carcinoma of the prostate (IDC-P) is a strong indicator of poor prognosis in prostate cancer (PCa). We utilized the Visium Spatial Gene Expression platform to characterize the gene expression profiles an...
Six-pattern p53 interpretation in 1293 vulvar squamous cell carcinomas: inter-pathologist variation and pattern distribution according to p16 status [0.03%]
1293例外阴鳞癌p53六种模式的判读差异及不同p16状态下的分布模式
Emma L Kaderly Rasmussen,Susanne K Kjær,Lise G Larsen et al.
Emma L Kaderly Rasmussen et al.
Aims: Vulvar squamous cell carcinoma (VSCC) is classified into human papillomavirus (HPV)-associated and HPV-independent types, primarily using p16 immunohistochemistry, with p53 staining playing a complementary role sinc...