Sclerosing stromal tumour: a clinicopathological study of 100 cases of a distinctive benign ovarian stromal tumour typically occurring in the young [0.03%]
硬化性基质瘤：年轻妇女易发的一种罕见的良性卵巢间叶肿瘤——100例临床病理分析
Kyle M Devins,Robert H Young,Jaclyn C Watkins
Kyle M Devins
Aims: Since the sclerosing stromal tumour (SST) of the ovary was first described in 1973, few studies have expanded upon its histological features or overlap with other tumours. We thus investigate these aspects based on ...
Programmed death-ligand 1 expression in human papillomavirus-independent cervical adenocarcinoma and its prognostic significance [0.03%]
程序性死亡配体-1在人类乳头瘤病毒阴性的宫颈腺癌中的表达及其预后的意义
Lili Chen,Elena Lucas,Xiaofei Zhang et al.
Lili Chen et al.
Aims: In the 2020 World Health Organization classification of female genital tumours, endocervical adenocarcinomas (ECAs) are subclassified into human papillomavirus (HPV)-associated (HPVA) and HPV-independent (HPVI) grou...
Assessment of proliferation in breast cancer: cell cycle or mitosis? An observational study [0.03%]
乳腺癌增殖评估：细胞周期还是有丝分裂？一项观察性研究
Ayat G Lashen,Michael S Toss,Ayaka Katayama et al.
Ayat G Lashen et al.
Background and aims: Proliferation is an important indicator of breast cancer (BC) prognosis, but is assessed using different approaches. Not all cells in the cell cycle are committed to division. This study aimed to char...
Observational Study
Histopathology. 2021 Dec;79(6):1087-1098. DOI:10.1111/his.14542 2021
Visual assessment of mitotic figures in breast cancer: a comparative study between light microscopy and whole slide images [0.03%]
乳腺癌的有丝分裂图象视觉评估：光镜与全片数字化图像的比较研究
Ayat Lashen,Asmaa Ibrahim,Ayaka Katayama et al.
Ayat Lashen et al.
Background and aims: Visual assessment of mitotic figures in breast cancer (BC) remains a challenge. This is expected to be more pronounced in the digital pathology era. This study aims to refine the criteria of mitotic f...
Comparative Study
Histopathology. 2021 Dec;79(6):913-925. DOI:10.1111/his.14543 2021
Primary high-grade non-anaplastic thyroid carcinoma: a retrospective study of 364 cases [0.03%]
以364例原发高级别非间变性甲状腺癌病例分析为基础的回顾性研究
Bin Xu,Julia David,Snjezana Dogan et al.
Bin Xu et al.
Aims: We aimed to study the clinicopathological and molecular features of high-grade non-anaplastic thyroid carcinomas (HGTCs), a carcinoma with a prognosis intermediate between those of well-differentiated carcinoma and ...
Epstein-Barr virus reactivation influences clonal evolution in human herpesvirus-8-related lymphoproliferative disorders [0.03%]
EB病毒的再激活影响HHV-8相关淋巴细胞增生性疾病的克隆演化
Massimo Granai,Mattia Facchetti,Virginia Mancini et al.
Massimo Granai et al.
Background: Human herpesvirus-8 (HHV8) is a lymphotropic virus associated with different lymphoproliferative disorders, including primary effusion lymphoma (PEL), multicentric Castleman's disease (MCD), diffuse large B-ce...
Case Reports
Histopathology. 2021 Dec;79(6):1099-1107. DOI:10.1111/his.14551 2021
High interobserver variability and frequent overdiagnosis of dysplasia in fundic gland polyps can be improved by detecting atypia on the surface epithelium and an abrupt transition to non-neoplastic cells [0.03%]
通过在表面上皮中检测出非典型性以及与非肿瘤性细胞的突然转变可以改善胃底腺息肉中发育不良高观察者差异和频繁过度诊断的现象
Christine E Orr,Debra Beneck,Jose Jessurun et al.
Christine E Orr et al.
Aims: Fundic gland polyps (FGPs) arise sporadically and in combination with familial adenomatous polyposis (FAP). Criteria for distinguishing low-grade dysplasia (LGD) from regenerative atypia in FGPs are not well establi...
NTRK-rearranged mesenchymal tumour with epithelioid features: expanding the morphological spectrum of NTRK-fused neoplasms [0.03%]
具有上皮样特征的NTRK重排间叶源肿瘤：扩大NTRK融合新生物形态学谱系范围
João Victor Alves de Castro,Felipe D&#x;Almeida Costa,Giovana Tardin Torrezan et al.
João Victor Alves de Castro et al.
Léonie Alran,Foucauld Chamming&#x;s,Sophie Auriol-Leizagoyen et al.
Léonie Alran et al.
Aims: Breast hamartomas are an under-recognised lesion because they lack a distinctive microscopic appearance. Microscopic diagnosis can often conclude 'no significant lesion' or 'normal breast tissue', leading to repeate...
Sentinel lymph node tumour burden using digital cell count estimation predicts outcomes in melanoma [0.03%]
使用数字细胞计数估计黑色素瘤 sentinel 淋巴结肿瘤负荷以预测结果
Emily M Hartsough,Daniel Miller,Ryan Shanley et al.
Emily M Hartsough et al.
Background and aims: Cutaneous melanoma often metastasises in primis to sentinel lymph nodes (SLNs). Currently, there is no standardized method of characterizing the micrometastatic tumour burden in SLN biopsies for melan...