Stress testing in the diagnosis and early screening of chronic thromboembolic pulmonary disease with and without pulmonary hypertension [0.03%]
肺高血压存在与不存在的慢性血栓栓塞性肺病诊断和早期筛查中的压力测试
Giorgia Tocci,Matteo Santi,Cipollini Viola et al.
Giorgia Tocci et al.
Background: Chronic thromboembolic pulmonary disease (CTEPD) and its hemodynamic counterpart chronic thromboembolic pulmonary hypertension (CTEPH) are long-term sequelae of acute pulmonary embolism (PE), often underdiagno...
The fat-heart entanglement and the role of 'osteopontin mechanics' in cardiometabolic senescence [0.03%]
心脏衰老中脂肪心与骨桥蛋白力学作用的关系研究
Cristina Michelauz,Fabrizio Montecucco,Luca Liberale et al.
Cristina Michelauz et al.
Background: Residual cardiovascular (CV) risk persists despite therapeutic advances. Obesity is heterogeneous, and visceral adipose tissue (VAT) dysfunction ('adiposopathy') complicates risk stratification. Osteopontin (O...
Association between Helicobacter pylori infection and Parkinson's disease: A systematic review and meta-analysis [0.03%]
幽门螺旋杆菌感染与帕金森病的关联：系统评价和荟萃分析
Chang Seok Bang,Md Hasanuzzaman,Jae Jun Lee et al.
Chang Seok Bang et al.
Background: Helicobacter pylori infection is epidemiologically linked to Parkinson's disease (PD), though findings remain inconsistent. This study aimed to determine whether patients with PD have a higher prevalence of H....
Amyloid-beta (1-40) peptide is associated with systemic metabolic health [0.03%]
淀粉样β（1-40）肽与全身代谢健康相关
Kateryna Sopova,Dimitrios Delialis,Evmorfia Aivalioti et al.
Kateryna Sopova et al.
Background: Amyloid-beta 1-40 peptide (Aβ40) has recently emerged as a blood-based biomarker of cardiovascular disease (CVD). However, whether plasma levels of Aβ40 are associated with metabolic traits in humans without...
Iron-related intercellular communication in the liver: Main players and mechanisms [0.03%]
铁依赖性肝细胞间通讯：主要参与者和机制
Óscar Fonseca,Paulo J Oliveira,Martina U Muckenthaler et al.
Óscar Fonseca et al.
Background: The liver is widely recognized as a central hub for metabolic processes. Additionally, it plays critical roles in immune responses and in the regulation of iron homeostasis. Liver disorders have a profound imp...
Sex differences in cholesterol metabolism and their association with SCORE2 cardiovascular risk based on cholesterol homeostasis markers and principal component analysis [0.03%]
基于胆固醇稳态标志物和主成分分析的性激素差异对SCORE2心血管风险的影响研究
Sandra Vladimirov,Tamara Gojković,Nataša Bogavac-Stanojevic et al.
Sandra Vladimirov et al.
Background: Sex-related differences in cholesterol metabolism may influence cardiovascular disease risk and outcomes. Understanding these differences in the context of SCORE2 predicted cardiovascular risk could support th...
Atherogenic dyslipidaemia and residual cardiovascular risk: Understanding the link to heart disease [0.03%]
致动脉粥样硬化性脂质异常和心血管残余风险：了解其与心脏病的联系
Gabriela O Girón,Sergi Otero,Panagiota Efstathia Nikolaou et al.
Gabriela O Girón et al.
Background: A significant proportion of patients continue to experience cardiovascular (CV) events despite achieving recommended low-density lipoprotein cholesterol (LDL-C) targets, a phenomenon referred to as residual CV...
Albumin, urea-to-albumin ratio, or the albumin-to-creatinine ratio to predict outcomes in heart failure with mildly reduced ejection fraction [0.03%]
预测射血分数轻度降低的心力衰竭患者预后的白蛋白、尿素与白蛋白比值或白蛋白与肌酐比值研究
Alexander Schmitt,Ibrahim Akin,Marielen Reinhardt et al.
Alexander Schmitt et al.
Background: This study investigates the prognostic impact of albumin, the urea-to-albumin ratio (UAR), and albumin-to-creatinine ratio (ACR) in patients with heart failure with mildly reduced ejection fraction (HFmrEF), s...
Cellular senescence in giant cell arteritis and polymyalgia rheumatica: From mechanisms to therapeutic opportunities [0.03%]
巨细胞动脉炎和多肌炎风湿症中的细胞衰老：从机制到治疗机会
Yiting Luo,Fan Yang,Yanlin He et al.
Yiting Luo et al.
Background: Giant cell arteritis (GCA) and (PMR) are inflammatory rheumatic disorders whose pathogenesis are unclear. The interleukin (IL)-6 receptor inhibitor is the first approved biologic agent for GCA and PMR, reducin...