Acute Myocarditis: From Pathophysiology to Risk-Stratified Management-A Clinical Review [0.03%]
急性心肌炎：从发病机制到分层管理-临床综述
Michele Golino,Marco Giuseppe Del Buono,Michele Marchetta et al.
Michele Golino et al.
Background: Acute myocarditis is an inflammatory disease of the myocardium with an annual incidence of 4-14 per 100,000 individuals, predominantly affecting young adults. Its clinical features are frequently nonspecific, ...
Early Hemolysis, Myolysis and Renal Stress Following Pentaspline Pulsed Field Versus Radiofrequency Ablation of Atrial Fibrillation [0.03%]
早期溶血、肌溶解和肾功能障碍的产生与五点标线脉冲场消融与射频消融治疗房颤的对比研究
Paul Felix Harbich,Lisa Auer,Florian Tinhofer et al.
Paul Felix Harbich et al.
Background: Pulsed field ablation (PFA) is an effective alternative to radiofrequency ablation (RFA) for pulmonary vein isolation (PVI) in atrial fibrillation (AF), offering procedural advantages and a favourable safety p...
Observational Study
European journal of clinical investigation. 2026 Aug;56(8):e70248. DOI:10.1111/eci.70248 2026
From Electrical Morphology to Physiological Dynamics: Lessons From ECG Adoption for the Clinical Integration of Heart Rate Variability [0.03%]
从心电图形态学到生理动力学：心率变异性临床整合的心电图采用教训
José Luis Puglisi,Gurpreet Sodhi,Samuel Minucci Carmargo et al.
José Luis Puglisi et al.
Background: Heart rate variability (HRV) has remained a relatively finite and niche tool in cardiology despite decades of research supporting its physiological and clinical relevance. This limited adoption may resemble th...
Systemic Inflammation and Risk of Thromboembolism, Mortality, and Treatment Response in Patients With Cancer Receiving Immune Checkpoint Inhibitors [0.03%]
系统性炎症与癌症患者接受免疫检查点抑制剂治疗的血栓栓塞、死亡和治疗反应风险的关系
Leyla Ay,Ingrid Pabinger,Matthias Preusser et al.
Leyla Ay et al.
Background: Immune checkpoint inhibitors (ICI) are widely used in cancer therapy, but biomarkers for thromboembolic risk, treatment response, and survival remain limited. We evaluated the association of systemic inflammat...
High-Intensity Statin Treatment Is Associated With Reduced Growth Differentiation Factor-15 in Patients With Coronary Artery Disease [0.03%]
高强度他汀治疗与冠心病患者生长分化因子-15降低有关
Konrad Stępień,Michał Ząbczyk,Joanna Natorska et al.
Konrad Stępień et al.
Background: Growth differentiation factor-15 (GDF-15) is upregulated in coronary artery disease (CAD). The relationship of intensive statin therapy with circulating GDF-15 levels has not been explored yet. In the current ...
Observational Study
European journal of clinical investigation. 2026 Jul;56(7):e70241. DOI:10.1111/eci.70241 2026
Pacemaker Status and 5-Year Mortality After TAVI: A Sex-Specific Analysis [0.03%]
经导管主动脉瓣植入后的起搏器状态与五年死亡率：一项基于性别的分析研究
Cecilia Veraar,Gudrun Lamm,Maximilian Will et al.
Cecilia Veraar et al.
Background: Sex-specific differences regarding the prognostic impact of permanent pacemaker (PM) implantation after transcatheter aortic valve implantation (TAVI) remain largely unexplored. ...
Carmine Zoccali,Giovanni Tripepi
Carmine Zoccali
The g formula is a cornerstone method for estimating causal effects of time-varying treatments using longitudinal observational data in the presence of time-varying confounders that are affected by prior treatment. Standard regression techn...
Improving Scientific Research: Renegotiated Principles of Science, Proposals, Failures, and Successes [0.03%]
改进科学研究：科学原理的重新谈判、建议、失败与成功
John P A Ioannidis
John P A Ioannidis
Science is a self-correcting process, and scientific research aims to improve adequacy, accuracy, and utility. However, improving scientific research is a demanding task, especially when currently some key principles of science are challeng...
Beta-Blockers After Myocardial Infarction With Preserved and Mildly Reduced Ejection Fraction: A Meta-Analysis With Trial Sequential Analysis [0.03%]
心功能保留及轻度降低的心肌梗死后β阻滞剂治疗的meta分析及试验序贯分析
Michele Maremmani,Paolo Gianfico,Christian Templin et al.
Michele Maremmani et al.
Aims: We aimed to evaluate the efficacy of β-blockers after myocardial infarction (MI) across left ventricular ejection fraction (LVEF) strata and to assess the conclusiveness of the available evidence using trial sequen...
Prognostic Role of Serum Albumin Levels in Elderly Patients With Non-Valvular Atrial Fibrillation [0.03%]
老年非瓣膜性房颤患者中血清白蛋白水平的预后价值分析
Giuseppe Armentaro,Giulia Crudo,Danilo Menichelli et al.
Giuseppe Armentaro et al.
Introduction: Atrial fibrillation (AF) is the most common arrhythmia in the elderly, and is associated with an increased risk of cardiovascular events (CVE). Hypoalbuminemia is an independent predictor of all-cause and ca...
Observational Study
European journal of clinical investigation. 2026 Jun;56(6):e70237. DOI:10.1111/eci.70237 2026