Practical considerations for the use of vericiguat in older patients with heart failure and reduced ejection fraction [0.03%]
用于射血分数降低的心力衰竭老年患者的维立西呱的实用考量
Francesco Castelletti,Elena Bianco,Giulia Fabro et al.
Francesco Castelletti et al.
Background: Worsening heart failure (WHF) is a red flag in the natural history of heart failure (HF) that negatively impacts the prognosis. Urgent improvements in the management of WHF, especially among HF with reduced ej...
Exercise-induced immune response in breast cancer patients during prehabilitation, neoadjuvant or adjuvant treatment: A systematic review and meta-analysis [0.03%]
系统综述与meta分析：乳腺癌患者在术前准备、新辅助或辅助治疗期间运动诱导的免疫反应
Simone Ubaghs,Kenza Mostaqim,Astrid Lahousse et al.
Simone Ubaghs et al.
Background: Adjuvant and neoadjuvant treatment for breast cancer (BC) such as chemotherapy and radiotherapy can lead to immune system impairment. Exercise is hypothesized to mitigate these effects by modulating immune res...
Increased levels of serum surfactant protein D are associated with cardiovascular disease incidence in the Spanish adult population: Di@bet.es study [0.03%]
血浆肺表面活性物质蛋白D水平与西班牙成人糖尿病患者心血管病发病率相关性：Di@bet.es研究
Wasima Oualla-Bachiri,Ana Lago-Sampedro,Eva García-Escobar et al.
Wasima Oualla-Bachiri et al.
Aims: Cardiovascular disease (CVD) remains the leading cause of mortality. New biomarkers are needed to improve CVD risk prediction. Several studies have reported associations between surfactant protein D (SP-D), an innat...
Can ammonia scavenging treat MASLD? Evaluating the evidence for L-ornithine L-aspartate-A systematic review [0.03%]
鸟氨酸-天冬氨酸治疗MASLD的疗效如何？一项系统综述
Abdulrahman Ismaiel,Vera Ciornolutchii,Stefan-Lucian Popa et al.
Abdulrahman Ismaiel et al.
Introduction: While hyperammonemia is traditionally associated with decompensated cirrhosis, emerging evidence suggests that disturbances in nitrogen homeostasis contribute to disease progression in earlier stages of stea...
Beyond glycemic control: How incretins are changing the cardiovascular trajectories of diabetes and obesity [0.03%]
超越血糖控制：肠泌肽如何改变糖尿病和肥胖症的心血管预后
Angelo Avogaro
Angelo Avogaro
Background: Diabetes mellitus is a leading global health concern. The parallel rise in obesity has exacerbated this burden, with projections suggesting over half of the adult population will be overweight or obese by 2050...
Improving end-of-life care in the cardiac intensive care unit: Navigating the challenge of timing palliative care intervention [0.03%]
心脏重症监护室临终期的改善：缓和治疗介入时机的挑战及应对策略分析
Simona Giubilato,Roberta Della Bona,Alessia Gambaro et al.
Simona Giubilato et al.
Background: Integrating end-of-life (EoL) care in cardiac intensive care units (CICUs) is particularly complex because it requires a shift from a purely curative approach to one that emphasizes symptom management, emotion...
Identification of a pathological feed-forward loop linking succinate, HIF1α signalling and vascular remodelling in abdominal aortic aneurysm [0.03%]
鉴定出病理前馈回路连接腹主动脉瘤中的琥珀酸、HIF1α信号和血管重塑
S Griepke,G L Tripodi,K L Kristensen et al.
S Griepke et al.
Background: Succinate is a metabolite with roles beyond energy production, including regulation of metabolic pathways, signalling and protein modifications. Abdominal aortic aneurysm (AAA) is a disease characterized by de...
Advancing urine-derived stem cells: Cryopreservation validation and sex-specific metabolism [0.03%]
尿源性干细胞的研究进展： cryopreservation验证和性别特异性代谢
Gonçalo José Martins Afonso,Carla Cavaleiro,Sofia Marlene Nunes et al.
Gonçalo José Martins Afonso et al.
Background: Urine-derived stem cells (UDSC) are an emerging, non-invasive source of human stem cells combining easy collection, broad accessibility and high patient compliance with multilineage differentiation capacity. H...
Minimizing ischemic and/or rewarming injury during preservation of porcine kidney grafts [0.03%]
降低猪肾移植器官保存期间的缺血和/或复温损伤
Charlotte von Horn,Laura Malkus,Thomas Minor
Charlotte von Horn
Claudia Bartalucci,Laura Mezzogori,Riccardo Schiavoni et al.
Claudia Bartalucci et al.
Background: Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among critically ill patients. In the intensive care unit (ICU), invasive candidiasis (IC), invasive pulmonary aspergillosis (IPA)...