Katja Schnidrig,Manovriti Thakur,Aleksandra Tuleja et al.
Katja Schnidrig et al.
Background: Lower extremity arterial disease (LEAD) affects over 200 million people globally and is largely driven by chronic vascular inflammation. However, the complex interplay between inflammatory pathways, their prog...
Angiopoietin-like protein 2 and mortality in patients with heart failure-Results from an observational study [0.03%]
血管生成素样蛋白2与心力衰竭患者的死亡率——一项观察性研究的结果
Eva Maria Brandtner,Andreas Leiherer,Barbara Larcher et al.
Eva Maria Brandtner et al.
Background: Heart failure is an advanced form of cardiovascular disease with a high mortality rate. Management of the condition is possible and blood-based biomarkers could help identify the most vulnerable patients. Ther...
ANGPTL8 is upregulated in subcutaneous adipose tissue at early term after bariatric surgery in patients living with obesity [0.03%]
肥胖患者代谢手术早期改善时皮下脂肪组织中血管生成素-like蛋白8的上调表达
Ester Martínez Negro,Pablo Fernández-García,Marina Martin-Taboada et al.
Ester Martínez Negro et al.
Objective: Our aim is to study proteomic and transcriptomic changes in the subcutaneous white adipose tissue (sWAT) from patients living with severe obesity at early term after bariatric surgery (BS). ...
Nationwide estimates of SARS-CoV-2 infection fatality rates and numbers needed to vaccinate for COVID-19 vaccines in 2024 in Austria [0.03%]
奥地利2024年COVID-19疫苗的SARS-CoV-2感染致死率和接种人数估算全国估计值
Uwe Riedmann,Martin Sprenger,John P A Ioannidis et al.
Uwe Riedmann et al.
Background: Post-pandemic years are characterized by widespread previous population immunization against COVID-19. Whether and for whom COVID-19 vaccinations are still justified is unclear. We use nationwide estimates of ...
Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine [0.03%]
脂质组学谱型揭示了糖尿病风险的性别差异：对精准医疗的意义
Ana F Pina,Maria João Meneses,Fabrizia Carli et al.
Ana F Pina et al.
Aims/hypothesis: Type 2 diabetes is a multifactorial condition whose greatest impact comes from its complications. We hypothesized that distinct insulin-derived mechanisms and lipid profiles discriminate sex differences a...
Revisiting tricuspid regurgitation: Historical insights and emerging research perspectives [0.03%]
三尖瓣反流的再思考：历史见解和新兴研究视角
Claudia Gonzalez-Cucharero,Gemma Vilahur,Marta Saura et al.
Claudia Gonzalez-Cucharero et al.
Background: Tricuspid regurgitation (TR), defined as the failure of proper leaflet coaptation during systole, is a common but often underrecognized valvular disorder. TR continues to rise, primarily due to population agin...
GLP-1 receptor agonists in patients with MGUS: A real-world propensity-matched study [0.03%]
MGUS患者中GLP-1受体激动剂的使用：真实世界倾向匹配研究
Anastasios Tentolouris,Ioannis Ntanasis-Stathopoulos,Charalampos Filippatos et al.
Anastasios Tentolouris et al.
Background: Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma cell disorder with potential progression to multiple myeloma (MM). Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have ...
A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered 'early'? [0.03%]
什么是早期炎症性及自身免疫性风湿病？
Elvis Hysa,Emanuele Gotelli,Carmen Pizzorni et al.
Elvis Hysa et al.
Background: Early diagnosis is pivotal for guiding the intensity of clinical monitoring, optimizing therapeutic strategies and preventing organ damage in inflammatory and autoimmune rheumatic diseases (IARDs). This review...
Clustered cardiometabolic risk in pregnancy and dysmenorrhea in offspring: Results from a prospective birth cohort study [0.03%]
基于前瞻性出生队列研究的妊娠期间聚集性心血管代际传递效应及子代痛经症状之间的关系研究
Siyu Zhou,Nikol Shkarpa,Cathy Brouwer et al.
Siyu Zhou et al.
Background: Dysmenorrhea, a common gynaecological complaint, is often underdiagnosed, particularly in adolescents. The Developmental Origins of Health and Disease hypothesis suggests that maternal cardiometabolic conditio...
Metabolic dysfunction-associated steatotic liver disease, insulin resistance and hepatocellular carcinoma: A deadly triad [0.03%]
与代谢功能异常相关的肝脂肪变性疾病、胰岛素抵抗和肝细胞癌：致命的三联征
Alfredo Caturano,Enes Erul,Roberto Nilo et al.
Alfredo Caturano et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a leading cause of chronic liver disease worldwide, driven by the increasing prevalence of obesity and insulin resistance (IR). IR, a...