Metabolic cell deaths in head and neck cancer: mechanisms, therapeutic potential, and challenges [0.03%]
头颈癌中的代谢性细胞死亡：机制、治疗潜力与挑战
Tong Wang,Xu Li,Xu Huang et al.
Tong Wang et al.
Background: Head and neck cancer (HNC) poses prominent clinical challenges: limited early diagnosis efficacy, suboptimal five-year survival after conventional treatment, over 60% of patients at advanced/metastatic stages,...
The predictive implications for stroke-associated infection and prognostic outcome of neutrophil to albumin ratio in Chinese patients with spontaneous intracerebral hemorrhage [0.03%]
中性粒细胞/白蛋白比率对自发性脑出血患者预测感染和预后的价值分析
Guangyong Chen,Tian Zeng,Jiaqi Huang et al.
Guangyong Chen et al.
Introduction: The Neutrophil to Albumin Ratio (NAR) stands out as a novel integrative inflammatory biomarker that is associated with the occurrence of stroke-associated infection (SAI). Our objective is to comprehensively...
Qing-Re-Xiao-Zheng-yi-qi formula protects renal function by stabilizing lysosomal membranes and inhibiting NLRP3-inflammasome-mediated pyroptosis in diabetic kidney disease [0.03%]
清热消徵义气对糖尿病肾病大鼠尿蛋白的改善作用及其机制研究
Lei Tian,Lin Wang,Yutong Wang et al.
Lei Tian et al.
Background: Qing-Re-Xiao-Zheng-Yi-Qi formula (QRXZYQF), based on the "Shen-Luo-Zheng-Jia" principles of traditional Chinese medicine, has been reported to reduce 24-hour urinary total protein in diabetic kidney disease (D...
Clinical development and guiding theory of transcranial magnetic stimulation: a literature review [0.03%]
经颅磁刺激的临床研发及其理论指导：文献综述
Zhanxiang Lin,Jinling Cheng,Cheng Tan et al.
Zhanxiang Lin et al.
Background: Transcranial magnetic stimulation (TMS) is widely used as a painless, non-invasive, and well-tolerated neuromodulation technique for various psychiatric and neurological disorders. Evidence from reviews, clini...
Associations between social factors and spinal pain-related disability in people with back pain and/or neck pain [0.03%]
社会因素与背痛和/或颈痛患者脊柱疼痛相关残疾之间的关联
Lisette Bijker,Margreet Ten Have,Gwendolyne G M Scholten-Peeters et al.
Lisette Bijker et al.
Purpose: Pain-related disability is often managed using the biopsychosocial model. However, social factors, such as living situation, financial hardship and employment status, are understudied. This study focused on the a...
Long-term effectiveness and safety of benralizumab in EGPA: a 3-year single-center experience [0.03%]
Benralizumab治疗EGPA长期有效性和安全性的单中心3年经验
Federica Davanzo,Luca Iorio,Marta Codirenzi et al.
Federica Davanzo et al.
Objectives: Benralizumab emerged as a promising treatment option for eosinophilic granulomatosis with polyangiitis (EGPA). This study assessed the long-term effectiveness and safety of benralizumab in patients with severe...
Net clinical benefit of patiromer for acute hyperkalemia: a post-hoc analysis of the reduce trial [0.03%]
评价patiromer治疗急性高钾血症净临床效益的回顾性分析：REDUCE试验的结果
Robert McArthur,W Frank Peacock,Jeff Budden et al.
Robert McArthur et al.
Introduction: Hyperkalemia (HK) is a common and potentially life-threatening electrolyte disturbance managed with potassium (K)-shifting medications and potassium binders. The use of K-shifting agents is a confounder when...
Randomized Controlled Trial
Annals of medicine. 2025 Dec;57(1):2581912. DOI:10.1080/07853890.2025.2581912 2025
Jun Zhao,Zhuanping Wang,Xuetao Wang et al.
Jun Zhao et al.
Introduction: Bradykinin (BK) and its primary receptor, the bradykinin 2 receptor (B2R), play pivotal roles in regulating oxidative stress. While B2R activation has traditionally been linked to elevated reactive oxygen sp...
Impact of early minimal residual disease assessment on the outcomes of patients with systemic light chain amyloidosis [0.03%]
早期最小残留病灶评估对全身轻链淀粉样变患者结局的影响
Xiaozhe Li,Meilan Chen,Junru Liu et al.
Xiaozhe Li et al.
Background: Systemic light chain (AL) amyloidosis is associated with a high mortality rate, particularly in the first year after diagnosis. Minimal residual disease (MRD) assessment plays a key role in the prognosis of AL...