Magnetic resonance imaging changes of thigh muscles in dermatomyositis patients with anti-Mi2 antibody [0.03%]
抗Mi2抗体皮肌炎患者大腿肌肉磁共振成像变化特点研究
Yikang Wang,Qingyue Yuan,Na Xu et al.
Yikang Wang et al.
Background: Anti-complex nucleosomal remodelling histone deacetylase (Mi2)-positive dermatomyositis (DM) is characterized by severe muscle damage. This study investigated muscle magnetic resonance imaging (MRI) features i...
Granulomatous inflammation in histopathological samples: examining the aetiological spectrum, diagnostic challenges, and future perspectives [0.03%]
肉芽肿性炎症的组织病理学谱系、诊断挑战及未来展望
Pilar Hernández-Jiménez,Mónica Sánchez de la Fuente,Jorge Macedo Pascual et al.
Pilar Hernández-Jiménez et al.
Background: Granulomas can be found in different tissues and are associated with a variety of processes. To understand the primary diagnoses is the aim of this study. ...
Exosomal delivery of METTL3 promotes M1 macrophage polarization by inducing miR-155-5p maturation via m6A modification [0.03%]
METTL3源微囊泡通过m6A修饰促进miR-155-5p成熟从而诱导M1型巨噬细胞极化
Xinyu Wu,Hongbo Gong,Jie Zhang et al.
Xinyu Wu et al.
Objective: Macrophage polarization and function are regulated by epigenetic mechanisms and microRNAs transported by exosomes; however, the specific mechanisms are not clear yet. The study aims to investigate whether exoso...
Evaluating the prognostic value of admission IL-8 and sST2 as biomarkers of early myocardial injury in severe community-acquired pneumonia [0.03%]
入院时IL-8和sST2作为社区获得性肺炎重症患者早期心肌损伤生物标志物的预后价值评估
Shanshan Liu,Lu Liu,Jian Dong
Shanshan Liu
Background: Myocardial injury in severe community-acquired pneumonia (SCAP) is often under-recognized, and interpretation of high-sensitivity cardiac troponin I (hs-cTnI) may be complicated by renal dysfunction and critic...
Beyond the role in motor function, entopeduncular nucleus, a critical neural hub in psychiatric disorders and sleep regulation [0.03%]
超越运动功能，黑质网状核在精神病和睡眠调节中的关键神经节点作用机制研究
Huaizhi Wang,Saboor Saeed,Nana Yan et al.
Huaizhi Wang et al.
Background: The entopeduncular nucleus (EP) is a major output nucleus of the basal ganglia and plays a critical role in integrating motor, emotional, and behavioral processes. Although traditionally linked to motor contro...
Impact of antithrombotic therapy on outcomes of incidental unruptured intracranial aneurysms in patients with ischemic stroke [0.03%]
抗栓治疗对缺血性卒中患者偶发性未破裂脑动脉瘤的影响
Chao Chen,Yiya Xu,Yingchao He et al.
Chao Chen et al.
Background: The coexistence of acute ischemic stroke (AIS) and unruptured intracranial aneurysms (UIAs) is relatively common, but the safety of antithrombotic therapy in this population remains uncertain. This study evalu...
Protocol for a cohort study: evaluating the effect of neoadjuvant immunochemotherapy on intraoperative remifentanil consumption during IoC2-guided anesthesia in elderly patients with esophageal cancer [0.03%]
新辅助免疫化疗对老年食管癌患者术中异丙酚和瑞芬太尼消耗影响的临床研究方案
Halisa Paerhati,Xinyang Hu,Yuchen Lu et al.
Halisa Paerhati et al.
Background: The influence of neoadjuvant immunochemotherapy (nICT) on intraoperative opioid consumption during esophagectomy for cancer is not well understood. IoC2 enables real-time antinociceptive depth monitoring. This...
Observational Study
Annals of medicine. 2026 Dec;58(1):2707864. DOI:10.1080/07853890.2026.2707864 2026
Robotic-assisted intracorporeal radical cystectomy with modified ileal conduit reduces ureteroileal anastomotic stenosis risk: a comparative study with laparoscopic surgery [0.03%]
改良式的回肠导管机器人辅助腹腔镜下经天然孔道根治性膀胱切除术可降低输尿管吻合口狭窄风险：与传统腹腔镜手术对比研究
Tengfei Gu,Roberta Gunelli,Ting Chen et al.
Tengfei Gu et al.
Background: This study aims to evaluate the clinical efficacy of an innovative robot-assisted totally intracorporeal antecolic modified ileal conduit procedure (robotic group) versus laparoscopic surgery (laparoscopic gro...
Comparative Study
Annals of medicine. 2026 Dec;58(1):2703361. DOI:10.1080/07853890.2026.2703361 2026
Short-term efficacy and safety of 5MHz fractional microneedle radiofrequency for facial rejuvenation: a prospective study [0.03%]
5兆赫分数型微针射频在面部年轻化中的短期疗效及安全性：一项前瞻性研究
Houhuang Qiu,Xixin Wu,Yutong Wu et al.
Houhuang Qiu et al.
Background: Facial aging is a multifactorial process driven by both intrinsic senescence and extrinsic environmental factors. Although fractional microneedle radiofrequency (FMR) is widely used for facial rejuvenation, cl...
Clinical Trial
Annals of medicine. 2026 Dec;58(1):2708398. DOI:10.1080/07853890.2026.2708398 2026
Development and internal validation of a nomogram for predicting postoperative bone nonunion in infectious spondylitis: a retrospective cohort study [0.03%]
预测感染性脊椎炎术后骨不连的列线图构建及内部验证：回顾性队列研究
Wentao Zhao,Lu Xing,Yongrui Yang et al.
Wentao Zhao et al.
Background: Postoperative bone nonunion remains a major complication after instrumented fusion for infectious spondylitis, with substantially higher rates than in aseptic spinal surgery. Existingmodels lack validation and...