Heterogeneity in the efficacy of bosentan for hypertensive nephropathy: a study on individualized benefit prediction models based on pathological subtyping and dynamic trajectories [0.03%]
波生坦治疗高血压肾病疗效异质性研究：基于病理分型和动态轨迹的个体化效益预测模型探索
Xiang Yu,XinYan Gong,BaoLong Wang et al.
Xiang Yu et al.
Background: Many patients with hypertensive nephropathy progress to chronic kidney disease (CKD). Targeting the core pathophysiological pathway of endothelin-1 activation, this study aimed to elucidate response patterns t...
The TRAP complex (SSR1-SSR4): mechanistic roles and therapeutic opportunities [0.03%]
TRAP复合体（SSR1-SSR4）：机制作用及治疗机会
Jiaqi Zhang,Xing Wan,Aixia Gong
Jiaqi Zhang
Background: Esophageal squamous cell carcinoma (ESCC) is a highly aggressive cancer with a poor prognosis, and its molecular mechanisms remain unclear. Our previous research identified the signal sequence receptor subunit...
Multiple electrolyte imbalances in hospitalized patients: a multimorbidity perspective from a large, retrospective cohort study [0.03%]
多病共存角度探究住院患者的多种电解质紊乱：一项大规模回顾性队列研究视角
Nan Jiang,Siyu Liang,Yuelun Zhang et al.
Nan Jiang et al.
Introduction: Multiple electrolyte imbalances (MEIs) are underexplored in hospitalized patients. We aimed to determine: (1) the prevalence and prognostic impact of MEIs; (2) the associations between electrolyte imbalance ...
Letter regarding 'the association between serum iodine concentration in the first trimester and foetal ultrasound biometric parameters and birth size among Chinese pregnant women' [0.03%]
关于“中国孕妇孕早期血碘浓度与胎儿超声生物物理参数及出生体格的关系”的信件
Jingjing Xu,Shuying Wang,Guopan Zhang
Jingjing Xu
Incidence and risk factors for malignancy in patients with incidental solitary pulmonary nodules: a systematic review and meta-analysis [0.03%]
孤立性肺结节患者恶性肿瘤的发生率和危险因素的系统评价和meta分析
Huiyu Zheng,Zhipeng Shao,Wensong Shi et al.
Huiyu Zheng et al.
Background: The increasing use of chest imaging has led to a higher detection rate of incidental solitary pulmonary nodules (SPNs), often causing patient anxiety. Determining the malignancy rate and associated risk factor...
Letter to editor: 'respiratory - swallow coordination training using bimodal signal biofeedback for patients with post - stroke dysphagia: a randomized controlled trial' [0.03%]
致编辑的信：关于“生物反馈在卒中后吞咽障碍患者吸气-吞咽协调训练中的应用：一项随机对照试验”的评论
Isha Goel,Subhasish Chatterjee,Mousumi Saha
Isha Goel
The diagnostic yield of a structured comorbidity workup in a real-life outpatient population with obstructive sleep apnea: a cross-sectional study [0.03%]
以阻塞性睡眠呼吸暂停的门诊人群为基础构建共病评估体系并进行诊断：横断面研究
Xiaolei Zhang,Huan Tang,Teng Han et al.
Xiaolei Zhang et al.
Background: Obstructive sleep apnea (OSA) is associated with multiple systemic complications. However, evidence-based recommendations for comorbidity screening remain sparse. This study aimed to evaluate whether a structu...
Observational Study
Annals of medicine. 2026 Dec;58(1):2622175. DOI:10.1080/07853890.2026.2622175 2026
Testicular ageing as a central hallmark of male senescence: characteristics, molecular mechanisms and emerging therapeutic strategies [0.03%]
睾丸衰老是男性衰老的核心特征：特点、分子机制和新兴的治疗策略
Jun Gao,Lixue Wang,Wanjun Li et al.
Jun Gao et al.
Background: The testis is a male-specific organ that plays a central role in spermatogenesis and androgen secretion. Testicular ageing is a hallmark of male senescence. However, the underlying mechanisms, as well as strat...
Comparative effectiveness of percutaneous coronary intervention strategies for coronary small-vessel disease: a network meta-analysis of randomized trials [0.03%]
冠状动脉小血管疾病的经皮冠状动脉介入治疗策略的疗效比较：随机试验的网络 meta 分析
Changjiang Deng,Chao Fan,Zhiyan Du et al.
Changjiang Deng et al.
Background: Coronary small-vessel disease (SVD) remains challenging for percutaneous coronary intervention (PCI) because small lumens magnify restenosis and ischemic risk. Multiple devices are available, yet their compara...