Comparison of liposomal bupivacaine and bupivacaine hydrochloride intercostal nerve blocks for postoperative analgesia after thoracic surgery: a multicenter, randomized, three arms trial protocol [0.03%]
用于胸部手术后镇痛的脂质体布比卡因与盐酸布比卡因肋间神经阻滞的多中心随机三臂试验方案：比较研究
Junyi Huang,Lihua Wang,Shiyou Wei et al.
Junyi Huang et al.
Introduction: Whether intercostal nerve block can fully realize the prolonged analgesic potential of liposomal bupivacaine remains uncertain. This study aims to evaluate whether liposomal bupivacaine administered via inte...
Wan-Gang Gu,Gui-Zhen Yin,Yan-Peng Zhang
Wan-Gang Gu
Background: Protease (PR) inhibitors (PIs) are widely regarded as the most significant agents in the treatment of human immunodeficiency virus (HIV) and have been instrumental in the success of highly active antiretrovira...
Choosing real-world data for clinical and epidemiological research: methodological lessons from NHIRD and TriNetX-A narrative review [0.03%]
面向临床和流行病学研究的真实世界数据选择：从NHIRD和TriNetX中获得的方法启示——综述文章
Teng-Li Lin,Yi-Ju Chen,Chun-Ying Wu
Teng-Li Lin
Introduction: Large-scale real-world data (RWD) are increasingly used in clinical and epidemiological research, although database-specific structures and limitations may affect study validity and applicability. The Taiwan...
Long-term mortality in pediatric sepsis: a systematic review and meta-analysis [0.03%]
儿童脓毒症的长期死亡率：系统回顾和荟萃分析
Yongbiao Lv,Jiayi Zheng,Junxiang Cai et al.
Yongbiao Lv et al.
Background: Pediatric sepsis represents a significant factor in the mortality rates among children, with survivors remaining highly fragile during the period following discharge. While in-hospital and short-term mortality...
Current research hotspots and difficulties of chronic prostatitis/chronic pelvic pain syndrome: neuroendocrine mechanism [0.03%]
慢性前列腺炎/慢性盆腔疼痛综合征当前研究热点与难点：神经内分泌机制
Bo Shao,Kaixiu Wu,Zhengkai Fan et al.
Bo Shao et al.
Background: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) presents a significant clinical challenge in urology. Traditional pathophysiological models emphasize infection and local inflammation; however, the l...
Response to letter regarding 'bidirectional association of daily steps with sarcopenia: a longitudinal study' [0.03%]
关于“步数与肌肉减少症双向关联的纵向研究”的来信回复
Yilun Wang,Ziying Wu,Yuqing Zhang et al.
Yilun Wang et al.
Coagulation dysfunction in children with secondary hemophagocytic lymphohistiocytosis: a comprehensive analysis [0.03%]
儿童继发性噬血细胞综合征凝血功能障碍的综合分析
Chaojun Duan,Qing Liao,Jiale Gong et al.
Chaojun Duan et al.
Objective: Coagulation dysfunction plays a critical role in the pathogenesis and prognosis of secondary haemophagocytic lymphohistiocytosis (sHLH) in children. This study aims to systematically analyze the coagulation pro...
Corneal macrophages and limbal stem cells: emerging roles in ocular surface regeneration [0.03%]
角膜巨噬细胞和角膜缘干细胞在眼表再生中的新兴作用
Yi Mao,Shangkun Ou,Wei Si et al.
Yi Mao et al.
Background: Corneal integrity and visual acuity rely on limbal stem cells (LSCs) and immune homeostasis. Macrophages, as critical immune regulators, are increasingly recognized for their roles in stem cell niche maintenan...