Dissolving microdroplet electroanalysis enables attomolar-level detection [0.03%]
溶解微滴电分析可在原子摩尔水平上检测分子
James H Nguyen,Ashutosh Rana,Savannah M Hatch et al.
James H Nguyen et al.
Trace detection is critical for identifying chemicals that would otherwise remain undetectable. While analytical techniques, such as spectroscopy, spectrometry, and electrochemical sensors, are effective at detecting low concentrations, ach...
A LEGO®-inspired pipette-free approach for a fully-integrated molecular diagnostic kit isothermally operated at near body temperature for the detection of antibacterial resistance [0.03%]
一种基于乐高的无需吸头的一步法集成分子诊断试剂盒的新方法，可在接近体温的恒温下操作，用于检测抗菌药物耐药性
Kieu The Loan Trinh,So Yeon Park,Hyunji Lee et al.
Kieu The Loan Trinh et al.
Herein, we introduce a LEGO®-inspired molecular diagnostic microdevice fully integrated with DNA extraction, loop-mediated isothermal amplification (LAMP), and colorimetric detection functionalities for rapid detection of antibacterial res...
A mass spectrometry-based proteomics strategy to detect long-chain S-acylated peptides [0.03%]
一种基于质谱的蛋白质组学策略用于检测长链S-酰化肽段
Samiksha Sardana,Andrea Trezza,Francine Rodrigues Ianiski et al.
Samiksha Sardana et al.
Long-chain S-acylation is the addition of long-chain fatty acids to cysteine residues on proteins. This lipid modification is essential for protein membrane association and signalling but presents analytical challenges due to both its hydro...
Determining the hydrodynamic diameters of nanoplastics via short-end capillary zone electrophoresis-Taylor dispersion analysis in tandem [0.03%]
基于短端毛细管区带电泳-泰勒展开分析联用技术测定纳米塑料的水动力学直径
Ebuka Anizoba,Alison Bain,Vincent T Remcho
Ebuka Anizoba
As plastics persist in the environment, they are broken down into smaller pieces through processes including UV degradation and mechanical forces. Current research focuses on developing analytical methods to characterize plastics
Assessment of wheat straw and corn cob-derived biochar in the design of a novel electrochemical sensor for the determination of carbendazim [0.03%]
评估小麦秸秆和玉米芯衍生生物炭在新型卡巴肼电化学传感器设计中的应用
Jasmina Anojčić,Sanja Mutić,Tamara Apostolović et al.
Jasmina Anojčić et al.
During the development of quick, inexpensive, and environmentally friendly analytical techniques like voltammetric methods, two distinct waste resources, wheat straw (WBC) and corn cob (CBC), were utilized to synthesize biochars (BCs) at tw...
Protoporphyrin-functionalized reduced graphene oxide as a novel sensing platform for the electrochemical determination of lead ions [0.03%]
用于电化学检测铅离子的新传感平台——与低氧化石墨烯相连的原卟啉素传感器
Lu Hou,Ping-Shan Wen,Jun-Chang Xue et al.
Lu Hou et al.
The development of simple, rapid, and sensitive techniques for quantifying toxic heavy metal ions is crucial due to their risks to human and environmental health. Herein, a protoporphyrin-functionalized reduced graphene oxide (PP-rGO) nanoc...
SERS mapping combined with explainable deep learning for exosome analysis to enhance lung cancer detection [0.03%]
结合可解释的深度学习的表面增强拉曼光谱映射技术在外泌体分析中提升肺癌检测能力
Hui Chen,Luyao Wang,Dandan Fan et al.
Hui Chen et al.
Exosomes are critical biomarkers for early cancer diagnosis and prognosis due to their rich biological information. Nevertheless, analyzing exosomal biomarkers comprehensively remains challenging. Surface-enhanced Raman scattering (SERS) ha...
A pyrene-modified carbon nanodot as a fluorescence nanosensor for nitroaniline herbicide detection and smartphone-assisted RGB analysis using hydrogel detection kits [0.03%]
一种荧光纳米传感器用于硝基苯胺除草剂检测及其基于水凝胶检测试剂盒的智能手机RGB辅助分析
Dilek Öztürk,Vildan Sanko,Alireza Khataee et al.
Dilek Öztürk et al.
Nitroaniline herbicides are widely used to combat broadleaf weeds, yet their high toxicity and persistence raise serious environmental and health concerns. Effective and sensitive detection of these herbicides in complex matrices such as so...
Cost-effective distance-based paper microfluidic sensor for hemoglobin quantification in human serum samples for rapid diagnosis and follow-up of blood disorders [0.03%]
一种低成本的距离型纸基微流控传感器用于人体血清中血红蛋白定量以快速诊断和监测血液疾病
Kawin Khachornsakkul,Natkrittaya Saengsawang,Elliot Friesen et al.
Kawin Khachornsakkul et al.
Blood disorders such as anemia are among the most prevalent and debilitating disease conditions worldwide that require routine monitoring. Hemoglobin is clinically used as a key indicator for the rapid diagnosis of these blood-based disease...
Assessment of IgG stability in a low pH elution buffer using ATR-FTIR spectroscopic imaging and microfluidics [0.03%]
采用ATR-FTIR光谱成像和微流控技术评估IgG在低pH洗脱缓冲液中的稳定性
Céline van Haaren,Bernadette Byrne,Sergei G Kazarian
Céline van Haaren
Monoclonal antibodies (mAbs) represent the largest class of biopharmaceuticals, playing a vital role in the treatment of a wide range of diseases. Although the production of high quality mAbs has significantly improved over the last three d...