An adaptive weighted polynomial baseline correction method for electrochemical aptamer-based sensors [0.03%]
一种用于电化学适配体传感器的自适应加权多项式基线校正方法
Zhijian Wen,Yasmin Liu,Emeka J Itumoh et al.
Zhijian Wen et al.
A background signal, or baseline, is typically a low frequency signal that compounds a target signal of interest and complicates the analysis of electrochemical biosensing data. Square Wave Voltammetry (SWV) has been widely used to acquire ...
Haider Hussain,Paulina Putko,Dariusz Gołowicz et al.
Haider Hussain et al.
We introduce composition gradients of the solvent as a powerful new dimension for NMR analysis on both high-field and benchtop instruments. Taking advantage of the differences in the density and miscibility of binary solvent mixtures with d...
Lyophilised colourimetric LAMP for visual readout with dual colour indicators [0.03%]
具有双重颜色指示剂的冻干可视化LAMP反应体系
Kenny Malpartida-Cardenas,Oliver W Stringer,Matthew L Cavuto et al.
Kenny Malpartida-Cardenas et al.
Loop-mediated isothermal amplification (LAMP) is increasingly recognised as a practical alternative to PCR for pathogen detection, offering rapid turnaround time, a constant operating temperature, and compatibility with a wide range of dete...
Dielectric barrier discharge ionization (DBDI) enables rapid analysis of new psychoactive substances with ion mobility-mass spectrometry [0.03%]
介质阻挡放电离子化结合离子淌度质谱可快速分析新型精神活性物质
Bradley B Garrison,Copeland R Johnson,Ralph Aderorho et al.
Bradley B Garrison et al.
New psychoactive substances (NPS) present a major public health crisis across the world due to their variable potency, constant evolution within the recreational drug community, and ability to skirt legal/policy regulations. Because of the ...
Stable focusing of proteins within a packed microbead bed by ion concentration polarization in a paper-based analytical device [0.03%]
基于纸基分析设备中离子浓度极化在充满微珠床内稳定聚焦蛋白质
Sommer Osman,Kira L Rahn,Quinlan G Pollak et al.
Sommer Osman et al.
Paper-based analytical devices (PADs), and particularly lateral flow assays (LFAs), provide many advantages for protein sensing in clinical and resource-limited settings. This class of devices is an important tool for point-of-care (POC) di...
A spatially invariant noise model for minimum noise fraction (MNF) denoising of hyperspectral datasets: applications to large-scale infrared spectroscopic pathology [0.03%]
一种用于高光谱数据集最小噪声分数(MNF)去噪的空间不变噪声模型：大规模红外光谱病理学的应用
Dougal Ferguson,Peter Gardner
Dougal Ferguson
Use of Minimum Noise Fraction (MNF) denoising, previously developed for remote sensing applications, is an increasingly popular denoising technique for Infrared (IR) imaging data. The original MNF method proposed by Green et al. along with ...
Focused traveling surface acoustic wave-based acoustofluidic chip for label-free cell sorting [0.03%]
一种基于聚焦式传播表面声波的无标记分选芯片及其分选方法
Jingxiang Deng,Yang Yang,Zixin Wang et al.
Jingxiang Deng et al.
Label-free and effective sorting of red and white blood cells based on their physical properties is crucial for subsequent single-cell analysis or immune cell engineering applications. However, cell sorting relying on the physical effects o...
A hollow-core fiber based optofluidic chip for rapid immunofluorescence detection with simultaneous enhancement of sensitivity and enrichment efficiency [0.03%]
一种基于空芯光纤的光流控芯片实现快速免疫荧光检测及其灵敏度和捕获效率的同步增强
Xiao Ren,Tian Wen,Yukai Liu et al.
Xiao Ren et al.
Although conventional ELISA is highly sensitive, its intricate workflow, significant background interference and dependence on laboratory infrastructure severely restrict its use for on-site testing. Lateral-flow assays (LFAs) are simple an...
Nadine Nieste,Steven W M Olde Damink,Ron M A Heeren et al.
Nadine Nieste et al.
Pancreatic cancer remains one of the deadliest malignancies, due to its highly aggressive tumour biology and often late diagnosis at advanced stages. Profound intratumour heterogeneity and a complex tumour microenvironment (TME) are critica...
Super-lightweight, low-cost and wireless water quality monitor for remote chlorine rate management in water-circulating cooling facilities [0.03%]
一种超轻便低成本无线水质监测设备用于远程循环冷却水余氯率管控
Masayuki Kawakami,Toshihiro Kasama,Tomomi Sato et al.
Masayuki Kawakami et al.
There is a growing demand for the continuous monitoring of residual chlorine in water-circulating cooling facilities to remotely maintain concentrations within an appropriate range. This study aims to develop a lightweight, low-cost, and wi...