Development of a light-initiated chemiluminescence system for the detection of human plasma p-tau181 [0.03%]
开发用于检测人类血浆p- tau181的光引发化学发光系统
Yang Yang,Xu Wang
Yang Yang
Phosphorylated tau 181 (p-tau181) is a promising biomarker for predicting and monitoring Alzheimer's disease (AD) neuropathology. However, existing commercial assays suffer from disadvantages such as high cost and insufficient detection sen...
A holistic approach to understanding biochemical degradation of human tissues using high resolution MALDI MS [0.03%]
基于高分辨MALDI质谱的人体组织生化降解的全面分析方法研究
Jerika Ho,Naomi L Stock,Vaughn Mangal et al.
Jerika Ho et al.
Estimating the postmortem interval (PMI) is crucial in medico-legal death investigations, but existing methods are highly influenced by environmental and physiological factors. This study proposes a novel biochemical strategy for PMI estima...
High-throughput DeepPRM-Stellar proteomics coupled with machine learning enables precise quantification of atherosclerosis-stroke progression biomarkers and risk prediction [0.03%]
高通量深度参数-恒星蛋白质组学结合机器学习能够精确量化动脉粥样硬化-中风进展生物标志物和风险预测
Ye Liu,Ouyang Hu,Zhenxin Wang et al.
Ye Liu et al.
Predicting the progression of asymptomatic large-artery atherosclerosis (LAA) to acute ischemic stroke (AIS) remains a significant challenge when relying solely on anatomical stenosis. To address this clinical gap, we integrated discovery-p...
Unusual response behavior of ion exchange-based potassium ion-selective nano-optodes based on bis(crown ether) neutral ionophores and a cationic solvatochromic dye [0.03%]
基于双冠醚中性离子载体和阳离子溶致变色染料的离子交换型钾离子选择性纳米光学传感器的非常规响应行为研究
Naoya Matsumoto,Kenji Sueyoshi,Tatsuro Endo et al.
Naoya Matsumoto et al.
In this study, we used three different potassium ionophores developed for ion-selective electrodes to fabricate nanoemulsion-type ion-selective optodes (NE-ISOs) with a pH-independent response mechanism based on cation exchange between a po...
NAFLD progression in metabolic syndrome: a Raman spectroscopy and machine learning approach in an animal model [0.03%]
代谢综合征状态下非酒精性脂肪肝病的进展：动物模型中拉曼光谱及机器学习的应用研究
Adán Ramírez,Guadalupe Donjuán-Loredo,Ricardo Espinosa-Tanguma et al.
Adán Ramírez et al.
Nonalcoholic fatty liver disease (NAFLD) is emerging as the leading cause of chronic liver disease in many regions, particularly in association with the rising prevalence of Metabolic syndrome (MetS), affecting more than 30% of the populati...
Room-temperature phosphorescence sensor array for the detection and discrimination of neonicotinoid insecticides based on a host-guest doping strategy [0.03%]
基于主客体掺杂策略的新型室温磷光传感器阵列用于新烟碱类农药的检测及鉴别研究
Caicai Liu,Ran Li,Peng Yun et al.
Caicai Liu et al.
Detection and discrimination of neonicotinoid insecticides (NNIs) are highly desired, but they are still challenging tasks owing to the minor differences in the molecular structures among the massive subtypes of NNIs. In this work, a room-t...
Colorimetric detection of bisphenol A in water: a smartphone-based sensor using inverse opal molecularly imprinted photonic crystal hydrogel [0.03%]
基于智能手机传感器的反向光子晶胶离子印迹技术在水相中检测双酚A
Sree Sanker S S,Subin Thomas,Dhanya P Jacob et al.
Sree Sanker S S et al.
Molecularly imprinted photonic crystal hydrogel (MIPCH) serves as a highly effective platform for the sensitive and selective detection of various analyte molecules. In this study, we present a smartphone-based inverse opal MIPCH (IOMIPCH) ...
Raman sensor assisted by cascade signal amplification for simultaneous detection of two extracellular antibiotic resistance genes [0.03%]
级联信号放大辅助拉曼传感器同时检测两种胞外抗生素抗性基因
Xinli Shi,Qi Wang,Yan Zhang et al.
Xinli Shi et al.
Accompanied by the widespread use of antibiotics, antibiotic resistance genes (ARGs) have rapidly proliferated in the environment, necessitating the urgent development of sensitive detection methods. However, most reported methods focus on ...
Conformation-induced ratiometric electrochemical aptasensor for the detection of aflatoxin B1 in urban wetland environments [0.03%]
用于城市湿地环境中黄曲霉毒素B1检测的构象诱导比率电化学生物传感器
Zhentong Zhu,Jiamin Fan,Xinzhong Zhang et al.
Zhentong Zhu et al.
Monitoring waterborne pathogens with high specificity and sensitivity is critical for public health and environmental safety. Herein, we developed a ratiometric electrochemical biosensing platform utilizing aptamer recognition-triggered, en...
A novel cataluminescence sensor for rapid detection of methanol at low working temperature based on Ni/CeO2 catalyst [0.03%]
一种基于Ni/CeO₂催化剂在低温下快速检测甲醇的催化发光传感器
Shufang Lou,Fangyuan Yuan,Zhenhua Qin et al.
Shufang Lou et al.
Cataluminescence (CTL) is an attractive chemiluminescence phenomenon that occurs at the gas-solid catalytic interface, and there is a strong anticipation for highly efficient CTL. Herein, Ni/CeO2 catalyst was successfully developed by using...