Cu single-atom catalyst-based flexible hydrogen peroxide electrochemical sensor with oxygen resistance for monitoring ROS bursts [0.03%]
一种基于铜单原子催化剂的柔性过氧化氢电化学传感器用于监测ROS爆发且可抵抗氧气干扰
Meihong Peng,Jing Jiang,Shutong Chen et al.
Meihong Peng et al.
The study of cellular responses linked to oxidative stress mechanisms is crucial in comprehending diverse physiological and pathological life processes, including mitochondrial dysfunction. Nonetheless, despite the interference of O2, the m...
MAGPIX and FLEXMAP 3D Luminex platforms for direct detection of miR-122-5p through dynamic chemical labelling [0.03%]
MAGPIX和FLEXMAP 3D Luminex平台通过动态化学标记直接检测miR-122-5p
Antonio Marín-Romero,Valerie Regele,Dajana Kolanovic et al.
Antonio Marín-Romero et al.
MicroRNAs (miRs) have emerged as promising biomarkers for diagnosing and predicting the prognosis of liver injury. This study aimed to compare the performance of two Luminex platforms, MAGPIX and FLEXMAP 3D, utilizing the innovative Dynamic...
Fusion data from FT-IR and MALDI-TOF MS result in more accurate classification of specific microbiota [0.03%]
傅里叶变换红外光谱和基质辅助激光解吸/电离飞行时间质谱融合数据可更准确地分类特定微生物群落
Wenjing Gao,Ying Han,Liangqiang Chen et al.
Wenjing Gao et al.
Microbes are usually present as a specific microbiota, and their classification remains a challenge. MALDI-TOF MS is particularly successful in library-based microbial identification at the species level as it analyzes the molecular weight ...
Small-molecule fluorescent probes for bioactive species in inflammatory disease: arthritis, pneumonia and hepatitis [0.03%]
用于炎症性疾病中小分子荧光探针的研究：关节炎、肺炎和肝炎
Xiaolei Zhang,Fuyan Tang,Wei Shu et al.
Xiaolei Zhang et al.
Inflammation as an adaptive response underlies a wide variety of physiological and pathological processes. The progression of inflammation is closely intertwined with various bioactive molecules. To dissect the biological mechanisms and phy...
Influence of bovine and human serum albumin on the binding kinetics of biomolecular interactions [0.03%]
牛血清白蛋白和人血清白蛋白对生物分子相互作用结合动力学的影响
Benjamin Charron,Alexandre Delorme,Caroline Dubois et al.
Benjamin Charron et al.
Bovine serum albumin (BSA) containing buffers are the standard blocking buffer in biosensing, yet human serum is the intended application for most clinical sensors. However, the effect of human serum albumin (HSA) on binding assays remains ...
An improved algorithm for resolving overlapping peaks in ion mobility spectrometry and its application to the separation of glycan isomers [0.03%]
改进的离子移动性谱峰解析算法及其在糖链异构体分离中的应用研究
Xiangyang Hu,Junfei Zhou,Junhui Li et al.
Xiangyang Hu et al.
Despite the popularity of ion mobility spectrometry (IMS) for glycan analysis, its limited structural resolution hinders the effective separation of many glycan isomers. This leads to the overlap of IMS peaks, consequently impacting the acc...
Visualization detection of mycotoxin patulin in fruit juices by a small-molecule fluorescent probe [0.03%]
一种用于检测果汁中灰霉毒素的荧光探针的方法研究
Rong Li,Zunpan She,Fang Zeng et al.
Rong Li et al.
The mycotoxin patulin is a common contaminant in rotten fruits, posing severe food safety risks and threats to human health. Developing a convenient, sensitive and reliable method for patulin detection is of utmost importance but remains ch...
New synthetic red- and orange-emitting luciferases to upgrade in vitro and 3D cell biosensing [0.03%]
用于体外和三维细胞生物传感的新合成红色和橙色发光酶
Maria Maddalena Calabretta,Denise Gregucci,Elisa Michelini
Maria Maddalena Calabretta
Bioluminescence (BL), i.e., the emission of light in living organisms, has become an indispensable tool for a plethora of applications including bioassays, biosensors, and in vivo imaging. Current efforts are focused on the obtainment of ne...
Parahydrogen hyperpolarized NMR detection of underivatized short oligopeptides [0.03%]
原初氢极化寡肽的核磁共振检测
Nele Reimets,Kerti Ausmees,Sirje Vija et al.
Nele Reimets et al.
Parahydrogen hyperpolarization has evolved into a versatile tool in NMR, allowing substantial sensitivity enhancements in analysis of biological samples. Herein we show how its application scope can be extended from small metabolites to und...
Unique development of a new dual application probe for selective detection of antiparallel G-quadruplex sequences [0.03%]
一种新型双应用探针的独特开发 用于反平行G-四链体序列的选择性检测
Vardhaman Babagond,Kariyappa Katagi,Anup Pandith et al.
Vardhaman Babagond et al.
G-Quadruplex (G4) structures play vital roles in many biological processes; consequently, they have been implicated in various human diseases like cancer, Alzheimer's disease etc. The selective detection of G4 DNA structures is of great int...