Interpretable machine learning model-driven electrochemical impedance spectroscopic analysis for the determination of nitrate, nitrite, and ammonium ions in water [0.03%]
K Reji,Ramakrishnan Vishnuraj,Adithyakrishna Narayanaswamy et al.
K Reji et al.
Rapid advances in materials chemistry and data-driven approaches have accelerated the development of aquatic chemical sensors, yet accurate, real long-term nutrient monitoring remains a significant challenge. Reliable real-time detection of...
Cellular level lipidomics of two-dimensional cultures of adherent gut epithelial cell lines confirms a metabolic switch [0.03%]
Qianying Xu,Jake A Penny,Emily Fraser et al.
Qianying Xu et al.
In vitro cell models of the gut epithelium, particularly those based on the Caco-2 and HT29-MTX cell lines, play an important role in studying the uptake and metabolism of nutrients and pharmaceuticals. Previous studies using mass spectrome...
Hui Ma,David M Raizen,Haim H Bau
Hui Ma
Caenorhabditis elegans exhibits multiple forms of taxis that couple sensation modalities to directed locomotion. Dissecting the genetic architecture underlying these behaviors requires scalable, high-throughput screening tools that convert ...
Zinc finger protein arrays in an epoxy-functionalized, pump-free microfluidic device for amplification-free, colorimetric detection of double-stranded DNA [0.03%]
Shaikh Al Mahmud Bhuiyan,Rylan Shumway,Christine Trinkle et al.
Shaikh Al Mahmud Bhuiyan et al.
Rapid pathogen detection is essential during the early stages of disease treatment, as timely identification directly influences the selection of appropriate therapeutic agents. Zinc finger domains can be engineered into customizable protei...
DNA nanotechnology for nucleic acid analysis: detection of RNA and dsDNA amplicons using a multifunctional DNAzyme nanomachine (DNM) [0.03%]
Muhannad Ateiah,Sofia S Zablotskaya,Maria S Rubel et al.
Muhannad Ateiah et al.
DNA has long been recognized as a promising material for biotechnological applications. Here, we demonstrate how DNA nanotechnology can enhance the sensing of practically important forms of nucleic acid analytes, including folded single-str...
Analysis of cholesterol-induced mechanical modulation of cell membranes by nanopipette-generated fluid flow [0.03%]
Shu-Yue Xu,Meng-Qi Zhao,Xin-Yue Liu et al.
Shu-Yue Xu et al.
Here, we report a label-free membrane oscillation strategy based on nanopipette-generated fluid flow to investigate cholesterol-induced mechanical alterations in living cell membranes. The assay relies on ionic current fluctuations to revea...
A metaproteomic platform for integrated host-pathogen-microbiota profiling in zebrafish larvae [0.03%]
一种用于斑马鱼幼虫宿主-病原体-微生物群综合谱学分析的平台技术
Javiera Ortiz-Severín,Antonia Ramos-Guzmán,Ian Pérez et al.
Javiera Ortiz-Severín et al.
Understanding host-pathogen-microbiota interactions requires analytical strategies capable of resolving multiple biological compartments within a single experimental framework. Here, we present a global metaproteomic workflow that enables t...
Monte Carlo-like peaks assignment using a time-resolved in situ NMR approach for complex reaction monitoring: a case study of the photodegradation of retinyl acetate [0.03%]
基于时间分辨原位核磁共振的类似蒙特卡洛峰分配法监测复杂反应：视黄醇乙酸酯光降解实例研究
Farwa Khalid,Chunchesh Malangi Gajendramurthy,Franz F Westermair et al.
Farwa Khalid et al.
Photoactive molecules are of central interest due to their roles in light-matter interaction and in biological systems, and their applications in technology and medicine. Many important photoactive molecules undergo photodegradation, which ...
Effect of O-acetylation on ketene and carbonyl yields from conventional and emerging cannabinoids [0.03%]
O-乙酰化对传统和新兴大麻素裂解产生乙烯基酮和羰基的影响
Rhianna L Evans,C Noel Corley,Haylee C Hunsaker et al.
Rhianna L Evans et al.
The pulmonary toxicant, ketene, has been observed from electronic (e-) cigarette vaping and dabbing (flash vaporisation) of acetylated compounds such as Vitamin E Acetate (VEA) and the O-acetates of select few cannabinoids. Yet for the majo...
Organoid models through the lens of metabolomics: a systematic review of experimental applications and analytical approaches [0.03%]
从代谢组学角度审视类器官模型：实验应用和分析方法的系统评价
Martina Lombardi,Andrea Ingenito,Antonietta Santoro et al.
Martina Lombardi et al.
Organoid models have transformed experimental biology by enabling three-dimensional systems that recapitulate tissue architecture, cellular heterogeneity, and metabolic activity patterns more faithfully than conventional in vitro cultures. ...
Review
The Analyst. 2026 Apr 24. DOI:10.1039/d6an00186f 2026