Protein migration via dissolution of ATP-stabilized condensate in a gradient of AMP [0.03%]
通过AMP梯度溶解ATP稳定凝聚物实现蛋白质迁移
Shikha Shikha,Sakshi Juneja,Subhabrata Maiti
Shikha Shikha
We report the condensate-forming tendency of bovine serum albumin (BSA) increases in the presence of adenosine triphosphate (ATP) in macromolecularly crowded media. However, in the presence of adenosine monophosphate (AMP), the condensate d...
Switchable N-H vs. C3-H carboxylation of indoles using dual-function reagents [0.03%]
含双功能试剂的吲哚N-氢与C3-氢的切换羧基化反应
Katherine E Marris,Jazmine T Thorne,Daniel J Ryder-Mahoney et al.
Katherine E Marris et al.
The carboxylation of indoles through a CO2 transfer reaction with carboxylate salts is described. By altering the reaction conditions either N-H or C3-H carboxylation can occur. The reaction is also applicable to the carboxylation of other ...
Aleksandra Tołoczko,Marcin Kaźmierczak,Vladyslav Maliuzhenko et al.
Aleksandra Tołoczko et al.
The coupling between the spin state and the complex motion of the individual alkyl chains results in a unique thermal hysteresis exhibiting an "inverted" loop. Specifically, the high-spin (HS) → low-spin (LS) transition upon cooling occurs...
Regioselective chalcogenation of glycals: DBU and iodine-mediated, transition-metal-free synthesis of heteroaryl thio- and seleno-glycoconjugates [0.03%]
糖醛衍生物的选择性含硫/硒化反应：DBU和碘介导的、不需要过渡金属参与的杂芳基硫醚/硒醚糖缀合物的合成
Pallavi Saha,Deepak K Sharma
Pallavi Saha
We report a transition-metal-free approach of regioselective C-2 chalcogenation of glycals, employing 2-thio- and 2-selenocyanato-glycals as chalcogen sources. Synergistic combination of DBU and catalytic iodine promotes the in situ generat...
An-Ping Koh,Gaël Vernezoul,Jun Fan et al.
An-Ping Koh et al.
This study describes a bis(N-heterocyclic carbene)-borylene that activates heteroallenes. The borylene undergoes a bora-Staudinger reaction with azide to afford an NHC-iminoborane, and also catalyzes the cyclotrimerization of isocyanates to...
Carbon dots in the generation of reactive oxygen species for antibacterial therapy: advances and challenges [0.03%]
用于抗菌治疗的碳点介导的活性氧生成：进展与挑战
Peiyao Chen,Li-Ge He,Hui Zhai et al.
Peiyao Chen et al.
Bacterial infections remain a major threat to global public health. While antibiotics have been the cornerstone of clinical antibacterial therapy, their efficacy is increasingly compromised by the emergence of resistant bacterial strains. T...
Unraveling the role of Co-O-Ni motifs in MOF-derived CoNi-LDH for the enhanced oxygen evolution reaction [0.03%]
揭秘MOF衍生CoNi-LDH中Co-O-Ni基元在提升氧析出反应性能中的作用
Di Li,Ruihui Gan,Yongping Zheng et al.
Di Li et al.
The electrocatalytic oxygen evolution reaction (OER) is a critical bottleneck in water splitting due to its sluggish kinetics. Herein, we developed a MOF-derived CoNi-LDH catalyst (MDCoNi-LDH) based on an in situ etching strategy. We demons...
A novel directed evolution platform for engineering chemically gated protein switches [0.03%]
一种用于工程化学门控蛋白开关的新型定向进化平台
Luis A Vázquez-Rivera,Jiaqi Shen,Gwendolyn Shingles et al.
Luis A Vázquez-Rivera et al.
Chemically gated protein switches have broad applications in regulating cellular activities. In this study, we introduce DuoSelect, a yeast surface selection platform for selecting protein switches based on signal-to-background ratios by co...
Unusual capacity boost in Li/TiF3 cells enabled by a Li+/Na+ mixed solid electrolyte with high-voltage stability [0.03%]
一种可在高电压下工作的锂/钠混合固态电解质用于提高Li/TiF3电池的容量性能
Kaisei Sano,Reona Miyazaki,Takehiko Hihara
Kaisei Sano
TiF3 exhibits an anomalously large capacity when paired with a Li+/Na+ mixed NaI-NaBH4-LiI electrolyte. TiF3 shows no Ti3+ redox during operation, indicating interfacial Li+ storage as the dominant process. The Li+/Na+ mixed electrolyte pro...
Degradation and interfacial chemistry of inorganic cathodes for potassium-ion batteries [0.03%]
钾离子电池无机正极材料的衰减与界面化学反应
Weiwei Sun,Shiyan Zhu,Mingxuan Gu et al.
Weiwei Sun et al.
Potassium-ion batteries (KIBs) have emerged as promising, cost-effective alternatives to lithium-ion batteries. However, their practical viability is still hampered by persistent instabilities associated with cathode materials and their int...