A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation [0.03%]
Banghao Zhou,Lixiang Guo,Yi-Chun Tsai et al.
Banghao Zhou et al.
Objective: While FLASH radiotherapy (FLASH-RT) is recognized for normal tissue sparing, its effect in mitigating the toxicity of late-responding organs remains uncertain, limiting clinical adoption. With its clinical impo...
Refining photon- and particle-induced chromosome aberration predictions for simplified and detailed radiation damage models [0.03%]
Shannon J Thompson,Kevin M Prise,Stephen J McMahon
Shannon J Thompson
Besides preferential tumour targeting, particle therapy has an increased relative biological effectiveness compared to X-rays, but uncertainties in this effectiveness prevent full exploitation of its clinical benefits. Mechanistic radiation...
Christopher B C Dean,Maria Laura Perez Lara,Emma Horton et al.
Christopher B C Dean et al.
To systematically assess the accuracy and computational performance of a newly proposed stochastic differential equation (SDE)-based model for proton beam dose calculation by benchmarking it against Geant4 in a set of simplified but increas...
Phantom-based residual error correction using individualized system estimates (PRECISE) -pushing the boundaries of geometric fidelity in MRI [0.03%]
Chad Harris,Curtis N Wiens,Taha Kashif et al.
Chad Harris et al.
Residual gradient non-linearity (GNL) distortions persist after vendor-supplied correction. This work describes and evaluates the performance of a method entitled Phantom-based Residual Error Correction using Individualized System Estimates...
Robust external-beam calibration of plastic scintillation detectors and uncertainty analysis for In-Vivo dosimetry in HDR brachytherapy [0.03%]
Chahrazed Ghannoudi,Marie-Claude Lavallée,Benjamin Côté et al.
Chahrazed Ghannoudi et al.
Objective: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that confirms correct dose delivery. This s...
Arianna Liles,John Whitaker,Kolade Agboola et al.
Arianna Liles et al.
Objective: AAPM Task Group Report 203 (TG203) recommends implantable cardiac pacemaker (ICP) dependent patients receive elevated precautions and that maximum dose rates to ICPs should be less than 0.2 Gy/min. Unfortunatel...
Average glandular dose prediction for breast model with patient-specific fibroglandular distribution in mammography and digital breast tomosynthesis: a machine-learning algorithms comparison [0.03%]
Alice Barcella,Rodrigo Trevisan Massera,Cristina Lenardi et al.
Alice Barcella et al.
Objective To investigate Machine Learning (ML) methodologies for predicting glandular dose conversion coefficients for breast models with patient-specific fibroglandular distribution (Γpatient) in digital mammography (DM) and digital breas...
Atmospheric pressure influence on the charge collection efficiency of air-vented ionization chambers in ultra-high dose per pulse electron beams for FLASH radiotherapy [0.03%]
Miguel Angel Flores-Mancera,Andreas Schüller,José Paz-Martín et al.
Miguel Angel Flores-Mancera et al.
This work studies the dependency of the charge collection efficiency (CCE) on the atmospheric pressure of commercial ionization chambers (ICs) using an ultra-high dose-per-pulse (DPP) electron beam and proves a theoretical model of this phe...
Automatic prompt-guided incremental fine-tuning for offset detection in radiotherapy patient positioning [0.03%]
Jing Zhang,Yang Liu,Yuchi Jiang et al.
Jing Zhang et al.
Objective: Radiotherapy (RT) requires accurate and consistent patient positioning to ensure precise radiation delivery and minimize unnecessary exposure to healthy tissues. Conventional workflows rely heavily on clinician...
End-to-end testing of an online adaptive radiotherapy workflow for liver tumors using a dynamic thoraco-abdominal anthropomorphic phantom [0.03%]
Anahita Bakhtiari Moghaddam,Raquel Figueiredo Augusto,Patrick Darremont et al.
Anahita Bakhtiari Moghaddam et al.
Adaptive radiotherapy (ART) requires robust end-to-end (E2E) testing tools capable of reproducing organ deformation, physiological motion, and multimodal imaging properties. The TAM-ARa (ThoracicAnthropomorphic Phantom withMotion forAdaptiv...