High-flux entangled photon generation via clinical megavoltage radiotherapy beams for quantum imaging and theranostics [0.03%]
基于临床兆伏特放射治疗束的高通量纠缠光子产生在量子成像和诊疗学中的应用研究
Gustavo Olivera,Bashkim Ziberi,Stephen Avery et al.
Gustavo Olivera et al.
Objective: To evaluate whether clinical megavoltage radiotherapy beams can function as dual-purpose sources that deliver therapeutic dose while simultaneously generating high-flux entangled 511 keV photon pairs for quantu...
AI-assisted cryo-dose estimation and tissue injury modeling for assessing side effects in MRI-guided prostate cryoablation: a retrospective study [0.03%]
基于人工智能的前列腺冷冻消融磁共振引导下的剂量估计及组织损伤建模和副作用评价:回顾性研究
Pedro Moreira,Mijia Ma,Nicholas P Fordham et al.
Pedro Moreira et al.

Focal therapy offers a middle ground between active surveillance and whole-gland treatment for patients with low- and intermediate-risk prostate cancer, aiming to eliminate tumor tissue while preserving surrounding structures. Among av...
A mechanistic and time-resolved analytical model of oxygen-mediated DSB fixation: bridging LET physics and hypoxic biology for predictive heavy ion radiotherapy [0.03%]
一种介导氧气固定的双链断裂的机理和时间解析分析模型:弥合LET物理和放射抵抗生物学,以进行预测性重离子放疗
Ladan Rezaee
Ladan Rezaee
Objective: This research outlines a time-resolved analytical model that predicts the chance of fixation of radiation-induced DNA double-strand breaks (DSBs) according to oxygen concentration, linear energy transfer (LET),...
Combining proton FLASH and spatially fractionated radiotherapy: experimental and simulation-based dosimetric characterization [0.03%]
结合质子FLASH和空间分割放射治疗:实验与模拟剂量学特征研究
Gulakhshan Mustafa Hamad,Yannick Poirier,Sina Mossahebi et al.
Gulakhshan Mustafa Hamad et al.
Background: Ultra-high dose rate (UHDR) proton therapy and spatially fractionated radiotherapy (SFRT) are two emerging techniques that independently offer enhanced tumor control and improved normal tissue sparing.Their in...
Study of the over-response of radiochromic films in ultra-high dose rate and dose per pulse electron beams [0.03%]
超高剂量率及脉冲剂量电子束射线橡胶片过响应现象研究
Felix Horst,Andreas Schüller,Ralf-Peter Kapsch et al.
Felix Horst et al.
Many pre-clinical experiments on FLASH radiotherapy, in which biological samples are irradiated at conventional and ultra-high dose rate (UHDR), make use of radiochromic films as an absolute dose reference because their response is typicall...
HU-to-density calibration curves using diagnostic CT for radiotherapy treatment planning: a feasibility study [0.03%]
基于诊断CT的HU值与电子密度校准曲线在放射治疗计划中的可行性研究
Miguel Martínez Albaladejo,Francisco Martínez Sánchez,David Ramos Amores et al.
Miguel Martínez Albaladejo et al.
Objective: Accurate radiotherapy dose calculation critically depends on reliable conversion of Hounsfield units (HU) to density, traditionally achieved through scanner‑specific calibration using dedicated simulation computed tomography (CT...
Clinical validation of perfusion imaging with pulmonary function test data using Voronoi-based discretization [0.03%]
基于Voronoi离散化的灌注成像与肺功能测试数据的临床验证
Jorge Cisneros,Caleb J Herrera,Yi-Kuan Liu et al.
Jorge Cisneros et al.
Accurate lung function assessment is essential for diagnosing and managing diseases like COPD, pulmonary emboli, and lung cancer. Single-photon emission computed tomography (SPECT) provides valuable 3D functional imaging of ventilation and ...
Diffusion skewness imaging using Q-space trajectory imaging with positivity constraints [0.03%]
基于正约束的Q空间轨迹成像扩散偏度影像学研究
Jun Li,Zan Chen,Zhaoyi Teng et al.
Jun Li et al.
Diffusion magnetic resonance imaging (dMRI) is a non-invasive technique used to characterize tissue microstructure by measuring the diffusion of water molecules. Conventional Q-space trajectory imaging (QTI) estimates diffusion using low-or...
Zhijia Wang,Xinyu Liu,Xing Chen et al.
Zhijia Wang et al.
Medical image registration serves as a cornerstone for precision diagnosis and treatment, particularly for dynamic organs like the lungs, where high deformability and complex motion patterns impose significant challenges. Traditional iterat...
Quantification of dual-state 5-ALA-induced PpIX fluorescence: methodology and validation in tissue-mimicking phantoms [0.03%]
双态5-氨基乙酰丙酸诱导的原卟啉IX荧光的量化:方法及组织仿体中的验证
Silvere Segaud,Charlie Budd,Matthew Elliot et al.
Silvere Segaud et al.
Quantification of protoporphyrin IX (PpIX) fluorescence in human brain tumours has the potential to significantly improve patient outcomes in neuro-oncology, but represents a formidable imaging challenge. Protoporphyrin is a biological mole...