Clinical progress of therapeutics and vaccines: Rising hope against COVID-19 treatment [0.03%]
治疗和疫苗的临床进展：对抗新冠肺炎治疗的新希望
Ravi Bandaru,Smruti Rekha Rout,Omkar S Kamble et al.
Ravi Bandaru et al.
Cases of deaths due to COVID-19 (COrona VIrus Disease-19) infection are increasing gradually worldwide. Immense research is ongoing to control this pandemic condition. Continual research outcomes are indicating that therapeutic and prophyla...
In silico investigations of heparin binding to SARS-CoV-2 variants with a focus at the RBD/ACE2 interface [0.03%]
计算模拟他汀类药物与SARS-CoV-2变异株结合：重点研究RBD/ACE2界面
Nemat Ali,Rehan Khan,Abdullah F AlAsmari et al.
Nemat Ali et al.
The increased infectivity and transmissibility of SARS-CoV-2 new variants were contributed largely by increase binding of receptor binding domain (RBD) domain of the Spike (S) protein to its cellular receptor ACE2 (Angiotensin-Converting En...
Clean and folded: Production of active, high quality recombinant human interferon-λ1 [0.03%]
无菌和可折叠的：活性高质量重组人干扰素-λ1的生产
Aram Shaldzhyan,Yana Zabrodskaya,Nikita Yolshin et al.
Aram Shaldzhyan et al.
Type III interferons exhibit antiviral activity against influenza viruses, coronaviruses, rotaviruses, and others. In addition, this type of interferon theoretically has therapeutic advantages, in comparison with type I interferons, due to ...
Repurposing the inhibitors of COVID-19 key proteins through molecular docking approach [0.03%]
基于分子对接的COVID-19关键蛋白抑制剂重定位研究
Huda Ahmed Alghamdi,Syed Awais Attique,Wei Yan et al.
Huda Ahmed Alghamdi et al.
The severe acute respiratory syndrome coronavirus 2, famous as COVID-19, has recently emerged as a novel virus and imposed an unrecoverable loss to global health and the economy. At present, no effective drug against COVID-19 is available a...
Artificial intelligence: Potential tool to subside SARS-CoV-2 pandemic [0.03%]
人工智能或可助力控制新型冠状病毒肺炎疫情扩散
Nishanth Gopinath
Nishanth Gopinath
Artificial intelligence (AI), a method of simulating the human brain in order to complete tasks in a more effective manner, has had numerous implementations in fields from manufacturing sectors to digital electronics. Despite the potential ...
Effect of microbial fuel cell operation time on the disinfection efficacy of electrochemically synthesised catholyte from urine [0.03%]
运行时间对尿素微生物燃料电池阴极电解液合成消毒效力的影响
I Merino-Jimenez,O Obata,G Pasternak et al.
I Merino-Jimenez et al.
Microbial fuel cells (MFCs) offer an excellent solution to tackle some of the major challenges currently faced by humankind: sustainable energy sources, waste management and water stress. Besides treating wastewater and producing useful ele...
Rapid determination of remdesivir (SARS-CoV-2 drug) in human plasma for therapeutic drug monitoring in COVID-19-Patients [0.03%]
快速测定人血浆中的瑞德西韦(新型冠状病毒药物)以进行新冠肺炎患者的治疗药物监测
Raghavendra Rao Pasupuleti,Pei-Chien Tsai,Vinoth Kumar Ponnusamy et al.
Raghavendra Rao Pasupuleti et al.
To tackle the harmful consequences of the widespread COVID-19 pandemic, a broad-spectrum anti-viral drug remdesivir (RDV) has gained the utmost attention recently due to its promising application in treating COVID-19 patients. However, a fa...
Isolation and detection of a KDEL-tagged recombinant cholera toxin B subunit from Nicotiana benthamiana [0.03%]
从尼科特尼亚•班哲明茄中分离和鉴定KDEL标记的重组霍乱毒素B亚单位
David A Morris,Micaela A Reeves,Joshua M Royal et al.
David A Morris et al.
Here we describe refined methods for the isolation and detection of a KDEL-tagged, plant-produced recombinant cholera toxin B subunit (CTB) that exhibits unique mucosal wound healing activity. The protein was transiently overexpressed in Ni...
Plant cell-secreted stem cell factor stimulates expansion and differentiation of hematopoietic stem cells [0.03%]
植物细胞分泌的干细胞因子刺激造血干细胞的扩增和分化
Xiaoting Wang,Uddhab Karki,Hasara Abeygunaratne et al.
Xiaoting Wang et al.
Ex vivo generation of red blood cells (RBCs) from hematopoietic stem cells (HSCs) used for blood transfusion represents one of the focuses in current regenerative medicine. However, massive production of HSCs-based RBCs requires a significa...
Topical review on nano-vaccinology: Biochemical promises and key challenges [0.03%]
纳米疫苗学的专题评论：生化前景与关键挑战
Tean Zaheer,Kaushik Pal,Iqra Zaheer
Tean Zaheer
Nanomaterials have wide-ranging biomedical applications in prevention, treatment and control of diseases. Nanoparticle based vaccines have proven prodigious prophylaxis of various infectious and non-infectious diseases of human and animal c...