Dissecting the physics of bacterial biofilms with agent-based simulations [0.03%]
基于代理的仿真解析细菌生物膜的物理特性
Kee-Myoung Nam,Changhao Li,Bastiaan J R Cockx et al.
Kee-Myoung Nam et al.
Biofilms are surface-attached bacterial communities encased within extracellular matrices (ECMs) of biopolymers that play many significant roles in health and society. Biofilms are versatile, living biomaterials that are resilient to a wide...
Advancements in fluorescence lifetime imaging microscopy Instrumentation: Towards high speed and 3D [0.03%]
荧光寿命成像显微镜技术的进展：朝向高速和三维方向的发展
Jongchan Park,Liang Gao
Jongchan Park
Fluorescence lifetime imaging microscopy (FLIM) is a powerful imaging tool offering molecular specific insights into samples through the measurement of fluorescence decay time, with promising applications in diverse research fields. However...
Rohit Unni,Mingyuan Zhou,Peter R Wiecha et al.
Rohit Unni et al.
For over a decade, machine learning (ML) models have been making strides in computer vision and natural language processing (NLP), demonstrating high proficiency in specialized tasks. The emergence of large-scale language and generative ima...
Understanding how bacterial collectives organize on surfaces by tracking surfactant flow [0.03%]
通过追踪表面活性剂的流动来理解细菌集体如何在表面上组织自己
Summer Kasallis,Jean-Louis Bru,Rendell Chang et al.
Summer Kasallis et al.
Swarming is a collective bacterial behavior in which a dense population of bacterial cells moves over a porous surface, resulting in the expansion of the population. This collective behavior can guide bacteria away from potential stressors ...
Rachel E Detwiler,Jessica R Kramer
Rachel E Detwiler
Mucus is an essential barrier material that separates organisms from the outside world. This slippery material regulates the transport of nutrients, drugs, gases, and pathogens toward the cell surface. The surface of the cell itself is coat...
Systems approaches to uncovering the contribution of environment-mediated drug resistance [0.03%]
系统方法揭露环境介导的药物抗性贡献
Marc Creixell,Hyuna Kim,Farnaz Mohammadi et al.
Marc Creixell et al.
Cancer drug response is heavily influenced by the extracellular matrix (ECM) environment. Despite a clear appreciation that the ECM influences cancer drug response and progression, a unified view of how, where, and when environment-mediated...
Atcha Hamza,Jairaman Amit,Evans Elizabeth L et al.
Atcha Hamza et al.
The immune system performs critical functions to defend against invading pathogens and maintain tissue homeostasis. Immune cells reside within or are recruited to a host of mechanically active tissues throughout the body and, as a result, a...
Chad R Snyder,Dean M DeLongchamp
Chad R Snyder
Organic semiconductors may be processed from fluids using graphical arts printing and patterning techniques to create complex circuitry. Because organic semiconductors are weak van der Waals solids, the creation of glassy phases during proc...
Overcoming the limitations of COVID-19 diagnostics with nanostructures, nucleic acid engineering, and additive manufacturing [0.03%]
利用纳米结构、核酸工程和增材制造克服COVID-19诊断的局限性
Nantao Li,Bin Zhao,Robert Stavins et al.
Nantao Li et al.
The COVID-19 pandemic revealed fundamental limitations in the current model for infectious disease diagnosis and serology, based upon complex assay workflows, laboratory-based instrumentation, and expensive materials for managing samples an...