Trends in hypofractionated radiotherapy use among patients with breast or prostate cancer: a multicenter study in Osaka, Japan [0.03%]
日本大阪多中心乳腺癌和前列腺癌患者的低分割放射治疗应用趋势研究
Toshiki Ikawa,Toshitaka Morishima,Kayo Nakata et al.
Toshiki Ikawa et al.
The uptake of hypofractionated radiotherapy in Japan is not well documented. This study examined trends in the proportion of patients with breast or prostate cancer who received hypofractionated radiotherapy, using hospital-based cancer reg...
Low- and high-dose-rate radiation exposure alters the cellular composition and dynamics of the rat mammary epithelium for weeks preceding carcinogenesis [0.03%]
辐射暴露改变小鼠乳腺上皮细胞的组成和动态preceding致癌作用持续数周
Kento Nagata,Yukiko Nishimura-Yano,Mayumi Nishimura et al.
Kento Nagata et al.
In animals, low-dose-rate radiation induces cancer at a reduced rate compared with a high-dose-rate at an identical cumulative dose, although the underlying mechanism is not well understood. The immediate responses of cells to irradiation a...
Hiroyuki Okamoto,Fuma Tojo,Kazuyoshi Kurita et al.
Hiroyuki Okamoto et al.
When electrons exceed the speed of light in a medium, they emit low-intensity visible light, known as Cherenkov emission (CE). This study proposes a novel CE-based quality assurance (QA) test for linear accelerators. A CE-based QA (C-QA) ph...
Evaluating the capability of large language models in radiotherapy through professional certification examinations in Japan [0.03%]
通过日本专业资格考试评估大型语言模型在放射治疗中的能力
Noriyuki Kadoya,Yoshiyuki Takahashi,Seiya Koga et al.
Noriyuki Kadoya et al.
Large language models (LLMs), such as ChatGPT and Grok, have rapidly advanced in natural language understanding and are increasingly being applied to specialized fields, including medicine. In this study, we evaluated the domain-specific kn...
Early radiobiological effects of flattening filter (FF) and flattening filter-free (FFF) beams and the radioprotective role of melatonin in rat brain: a preclinical study [0.03%]
调Q自由扇束CT系统中材料分解的可行性研究：以NaI(Tl)探测器为例
Şule Baz Baz Çifci,Serhat Aras,Fatih Hacımustafaoğlu et al.
Şule Baz Baz Çifci et al.
The study aimed to investigate early radiobiological effects of Flattening Filter (FF) and Fattening Filter-Free (FFF) beams on brain tissue in experimental rat models and to evaluate the potential radioprotective role of melatonin (MEL) us...
Abscopal-like antitumor effect induced by localized low-temperature plasma application of normal tissue in mice [0.03%]
低温等离子体局部作用于正常组织诱导小鼠的类似远隔效应的抗肿瘤作用
Ryo Ono,Ryota Sumitomo,Kengo Wada et al.
Ryo Ono et al.
We have previously reported that the localized application of gaseous plasma to normal tissues suppresses distant tumor growth in mice, resembling the abscopal effect of radiotherapy. Plasma, a partially ionized gas generated by a high-volt...
Imaging dose in image-guided radiotherapy for localized prostate intensity-modulated radiotherapy: a nationwide survey in Japan [0.03%]
日本全身范围内的影像引导放射治疗的前列腺调强放疗 imaging剂量：一项全国性调查
Satoshi Kito,Takeshi Takizawa,Satoshi Tanabe et al.
Satoshi Kito et al.
This study aimed to establish the diagnostic reference levels (DRLs) of imaging doses for image-guided radiotherapy (IGRT) used in intensity-modulated radiotherapy for prostate cancer in Japan. A nationwide survey was conducted to gather da...
Machine learning-DeepSurv prediction model integrating mpMRI radiomics and genomic biomarkers for BCR-free survival and tumor response in prostate radiotherapy [0.03%]
基于mpMRI影像组学和基因标志物的前列腺癌放疗无生化复发生存及肿瘤反应机器学习-DeepSurv预测模型
Hossein Taheri,Mohammadbagher Tavakoli,Maryam Farghadani et al.
Hossein Taheri et al.
The purpose of this study was to design a radiogenomics machine learning-DeepSurv model for biochemical recurrence-free (BCR-free) survival and treatment response (TR) prediction for radiotherapy (RT) of prostate cancer (PCa). In this study...
Impact of off-center diagonal profile depth pairing on gamma pass rates in portal dosimetry [0.03%]
门户剂量学中非中心对角剖面深度配对对γ通过率的影响
Yuya Suzuki,Atsushi Yamashita,Yoshiaki Okada et al.
Yuya Suzuki et al.
This study evaluated the impact of off-center diagonal (OCD) profile depth pairing between the treatment planning system (TPS) and the electronic portal imaging device (EPID) on gamma pass rates in portal dosimetry. In clinical workflows, O...
18F-BPA as a surrogate tracer for BPA in BNCT: comparative analysis of transport mechanisms and biodistribution [0.03%]
18F-BPA作为BNCT中BPA的示踪剂：运输机制及生物分布的比较分析
Li Li,Xiaoping Sun,Fu Lin et al.
Li Li et al.
4-Borono-L-phenylalanine (BPA) is a key 10B carrier used in boron neutron capture therapy (BNCT), while its PET tracer analogue, 4-borono-2-18F-fluoro-L-phenylalanine (18F-BPA), enables non-invasive visualization of tumour boron uptake. Sin...