Feasibility of retrieval-augmented generation for large language models with Japanese input in radiotherapy [0.03%]
基于检索增强生成的大模型在放射治疗中的日文输入可行性研究
Yoshiyuki Takahashi,Noriyuki Kadoya,Kazuhiro Arai et al.
Yoshiyuki Takahashi et al.
Large language models (LLMs) have recently gained attention for their potential. However, concerns remain regarding their reliability due to limitations such as hallucinations and insufficient domain-specific knowledge. Retrieval-augmented ...
Fundamental evaluation of a novel upright shield to protect medical personnel from scattered radiation during endoscopic retrograde cholangiopancreatography using a C-arm system [0.03%]
一种新型直立防护罩的理论评估结果：在使用C形臂系统的内镜逆行胰胆管造影术中保护医务人员免受散射线的影响
Hiroki Ishii,Koichi Chida,Yohei Inaba et al.
Hiroki Ishii et al.
Medical personnel performing endoscopic retrograde cholangiopancreatography (ERCP) are at a high risk of developing radiation-induced injuries, such as cataracts, due to scattered radiation, making the use of appropriate radiation protectio...
Deep learning-based dose prediction in proton beam therapy for hepatocellular carcinoma: comparison of network architectures and loss functions [0.03%]
基于深度学习的质子束治疗肝细胞癌剂量预测：网络结构和损失函数的比较
Shuta Ogawa,Noriyuki Kadoya,Takahiro Kato et al.
Shuta Ogawa et al.
In proton beam therapy (PBT) for hepatocellular carcinoma (HCC), deep learning (DL)-based dose prediction offers clinical value by providing immediate reference dose distributions as a guideline tool for treatment planners and enabling virt...
Feasibility of nonspinal bony landmark-based image registration in CyberKnife ® robotic radiotherapy for pelvic and femoral bone tumors [0.03%]
基于非脊柱骨性解剖标志的图像配准在CyberKnife立体定向机器人放射治疗盆腔及股骨肿瘤中的可行性研究
Yasuhide Miyabe,Hiromu Yamanaka,Hiroto Seki et al.
Yasuhide Miyabe et al.
In stereotactic body radiotherapy for bone metastases using the CyberKnife system, spinal anatomy is generally employed as the alignment reference. However, when treating pelvic tumors such as those in the pubic bone or proximal femur, the ...
BMSCs alleviate inflammation and inhibit apoptosis in radiation pneumonitis treatment by modulating the NF-κB/NLRP3 signaling pathway [0.03%]
骨髓间充质干细胞通过调节NF-κB/NLRP3信号通路缓解放射性肺损伤炎症并抑制细胞凋亡
Yiwei Song,Yuxin Wen,Huaqing Zhai et al.
Yiwei Song et al.
Radiation pneumonitis (RP) is a severe consequence of thoracic radiation, and its pathophysiology is tightly linked to NLRP3 inflammasome-mediated hyperinflammatory reactions. The nuclear factor κB (NF-κB) signaling system, which regulate...
Endovascular pulmonary arterial fiducial marker placement for particle radiotherapy using proton or carbon-ion beams for lung cancer [0.03%]
经血管肺动脉定位标记物植入术用于肺癌颗粒放射治疗
Kazuki Terashima,Tomoyuki Gentsu,Daiki Takahashi et al.
Kazuki Terashima et al.
This study evaluated the safety, feasibility and efficacy of endovascular pulmonary arterial fiducial marker (EVFM) placement for image-guided particle therapy using proton or carbon-ion beams in patients with primary or metastatic lung can...
Masanori Machida,Takashi Ono,Koki Ando et al.
Masanori Machida et al.
Few studies have evaluated the efficacy of proton beam therapy (PBT) for external auditory canal cancer (EACC) or middle ear cancer (MEC). Therefore, the present study aimed to evaluate the efficacy and toxicity of PBT for EACC and MEC. Bet...
Feasibility and treatment outcomes of simultaneous definitive chemoradiotherapy for elderly patients with synchronous hypopharyngeal and esophageal squamous cell carcinoma [0.03%]
同步放化疗治疗老年同期发生喉咽和食管鳞癌患者的可行性及其疗效分析
Yuki Wada,Tetsugaku Shinozaki,Satoshi Kumagai et al.
Yuki Wada et al.
Hypopharyngeal and esophageal squamous cell carcinoma may occur synchronously; however, optimal treatment strategies, particularly for elderly patients, remain undefined. We evaluated the feasibility and outcomes of simultaneous definitive ...
Quantitative analysis of autophagic flux reveals radiation-induced activation of SQSTM1-mediated degradation of protein aggregates and ER-phagy [0.03%]
定量分析自噬流量揭示辐射诱导的SQSTM1介导的蛋白质聚集和内质网吞噬作用
Takahito Moriwaki,Tsuyoshi Masuda
Takahito Moriwaki
Autophagy is an evolutionarily conserved process that degrades and recycles intracellular components through lysosomes, thereby maintaining cellular homeostasis under stress conditions. Although radiation is known to influence autophagy, mo...
Restorative effect of Rehmanniae radix praeparata on T-cell and NK-cell-mediated immune reconstitution in mice following radiation-induced injury [0.03%]
制备玄参根对放射损伤小鼠T细胞和NK细胞介导的免疫重建的影响
Xiaodan Zheng,Hongyun Lan,Yuhai Hu et al.
Xiaodan Zheng et al.
Functional impairment of T and NK cells following irradiation (IR) undermine anti-tumor immune responses. This study aimed to investigate the characteristics of T-cell and NK-cell reconstitution in mice following low-dose radiation-induced ...