NOP58 modulates radiosensitivity in non-small cell lung cancer via DDX18-mediated DNA damage repair [0.03%]
NOP58通过DDX18介导的DNA损伤修复调节非小细胞肺癌放射敏感性
Yiqian Jiang,Weijun Zhang,Yanhong Bao et al.
Yiqian Jiang et al.
Non-small cell lung cancer (NSCLC) constitutes 80-85% of lung cancers, with advanced cases showing a 20-30% 5-year survival rate. Radiation resistance limits radiotherapy efficacy, and the function of NOP58 in this process is unknown. This ...
Cost-effectiveness analysis of intensity modulated radiation therapy versus robot-assisted radical prostatectomy for patients with low-risk prostate cancer in Japan [0.03%]
日本低危前列腺癌患者强度调制放射治疗与机器人辅助根治性前列腺切除术的成本效益分析
Ataru Igarashi,Keiichi Jingu,Kaoru Ito et al.
Ataru Igarashi et al.
This study evaluated the cost-effectiveness of hypofractionated intensity-modulated radiation therapy delivered in 20 fractions (IMRT-20) compared with robot-assisted radical prostatectomy (RARP) for patients with localized low-risk prostat...
First clinical implementation of dynamic tumor-tracking volumetric modulated arc therapy with a gimbal-mounted linac: short delivery time and high precision [0.03%]
基于万向支架直线加速器的动态肿瘤跟踪容积旋转调强放射治疗技术首次临床应用：短治疗时间和高精度
Noriko Kishi,Mitsuhiro Nakamura,Hideaki Hirashima et al.
Noriko Kishi et al.
Dynamic tumor tracking (DTT) is an effective respiratory motion management strategy for thoracic and abdominal tumors and enables treatment delivery under free breathing using gimbal-mounted linac, without requiring breath-holding. To date,...
Yuhei Koike,Satoaki Nakamura,Hodaka Numasaki et al.
Yuhei Koike et al.
Daily attendance requirements for radiotherapy (RT) make geographic accessibility a critical determinant of treatment adherence and completion. Although facility surveys indicate that advanced modalities such as intensity-modulated radiothe...
Time-dependent 53BP1 foci kinetics in X-irradiated human hair follicle dermal papilla cells [0.03%]
X射线辐照人毛乳头细胞中时间依赖性的53BP1斑点动力学研究
Daisuke Hanamiya,Reo Etani,Mitsuaki Ojima
Daisuke Hanamiya
We investigated the feasibility of a biological dosimetry method using human hair follicle dermal papilla cells (HFDPCs). Cultured HFDPCs were X-irradiated at doses of 50-20 000 mGy, and 53BP1 foci were analyzed up to 96 h post-irradiation ...
Competitive cell transplantation in rat mammary tissue and its use for radiation-induced cell competition and tumor clonality assays [0.03%]
大鼠乳腺组织中的竞争性细胞移植及其在辐射诱导的细胞竞争和肿瘤克隆性检测中的应用
Kento Nagata,Yukiko Nishimura-Yano,Ayaka Hosoki et al.
Kento Nagata et al.
Competitive transplantation of cells expressing distinct fluorescent proteins is an attractive method for assessing cell competition and tumor clonality, albeit its use has been limited to mouse models. Rat mammary cancer is an alternative ...
Development and clinical application of biological dosimetry technology: insights from the HICARE/IAEA 2025 international training course [0.03%]
生物剂量计技术的研发及其临床应用——HICARE/国际原子能机构2025国际培训班见闻与思考
Wanwisa Sudprasert,Oleg Belyakov,Satoshi Tashiro
Wanwisa Sudprasert
The HICARE/IAEA 2025 International Training Course on Biological and Internal Dosimetry, held at Hiroshima University from 10 to 14 February 2025, convened 20 participants from nine countries- Brazil, Indonesia, Japan, Korea, the Philippine...
Salvage stereotactic body radiotherapy for post-prostatectomy recurrence: are we almost there? [0.03%]
前列腺切除术后立体定向放疗治疗复发性前列腺癌：我们准备好了吗？
Zhe Chen,Van Ton Tran,Masaki Matsuda et al.
Zhe Chen et al.
The use of hypofractionated radiotherapy (HFRT) after prostatectomy has expanded because of its radiobiological advantages and its potential to reduce treatment burden. Stereotactic body radiotherapy (SBRT), an even more condensed treatment...
Effect of tumor size on motion tracking and dosimetric accuracy using Radixact Synchrony [0.03%]
放射肿瘤大小对Radixact Synchrony运动追踪及剂量准确性的影响研究
Ryoto Kaido,Akihiro Takemura,Kakeru Sato et al.
Ryoto Kaido et al.
This study aimed to evaluate how planning target volume (PTV) size influences treatment-planning parameters and their relationship to tracking and irradiation accuracy. A high-resolution two-dimensional diode array mounted on a motion phant...
Willingness to engage in nuclear or radiological emergency response among medical personnel at four university hospitals in Kyushu, Japan [0.03%]
日本九州4所大学医院医务人员参与核事故或辐射应急反应意愿的调查分析
Arkhat Omarbek,Keita Iyama,Takanobu Otaguro et al.
Arkhat Omarbek et al.
Following the Fukushima Daiichi Nuclear Power Plant accident, Japan enhanced its nuclear disaster preparedness framework. However, personnel shortages stemming from fear and anxiety persist as a critical issue during such disasters. This st...