Difference in the Association between Growth Differentiation Factor 15 and Coronary Calcified Plaque According to Chronic Kidney Disease [0.03%]
慢性肾脏病患者GDF-15与冠状动脉钙化斑块相关性的差异性研究
Hayato Shimizu,Satoshi Hoshide,Hiroshi Funayama et al.
Hayato Shimizu et al.
Growth differentiation factor-15 (GDF-15), a member of the TGF-beta superfamily, is upregulated in response to tissue ischemia and proinflammatory cytokines that promote the onset and progression of atherosclerosis. Given that GDF-15 is als...
Impact of the Environmental and/or Modifiable Factors on the Clinical Characteristics of Cardiomyopathies [0.03%]
环境和/或可改变因素对心肌病临床特征的影响
Takashi Hiruma,Hiroyuki Morita
Takashi Hiruma
Xuejiao Wu,Fang Liu,Le Jin et al.
Xuejiao Wu et al.
Atrial fibrillation (AF) is a common arrhythmia that can reduce the quality of life of patients. Observational studies have reported that work and sleep are associated with the development of AF, but the causal relationship is unclear.Based...
Sirtuin-3 Regulates the Mechanism of Doxorubicin-induced Cardiotoxicity [0.03%]
Sirtuin-3调节多柔比星致心肌毒性的机制
Cheng Zhang,Dan Shi,Ping Yang
Cheng Zhang
Doxorubicin (DOX) is a widely used and efficacious anthracycline in clinical practice for the treatment of various tumors; however, a major limitation of DOX therapy is its cardiotoxicity, which significantly restricts its clinical applicat...
Nicotine Induces Fetal Cardiac Dysfunction by Promoting Cardiomyocyte Apoptosis Through Regulating the KCTD10-Notch Signaling [0.03%]
尼古丁通过调节KCTD10-notch信号促进心肌细胞凋亡诱导胎儿期心脏功能障碍
Lilin Zhong,Xiaoqing Yang,Huifen Zhang et al.
Lilin Zhong et al.
Congenital heart defects (CHD) are internal risk factors that cause cardiac dysfunction. Maternal smoking is a cause of inducing CHD and cardiac dysfunction. Here, we aimed to investigate the influence of nicotine on fetal cardiac dysfuncti...
Risk Factors and Construction of a Predictive Model for Postoperative Early Cognitive Dysfunction in Aortic Dissecting Aneurysms [0.03%]
主动脉夹层术后早期认知功能障碍的风险因素及预测模型构建
Lu Ding,Yinhuan Xu,Guangpu Fan
Lu Ding
This study aimed to investigate the factors influencing cognitive dysfunction in patients with aortic dissection after surgery and to construct a risk prediction model for it.This retrospective study analyzed 122 patients with aortic dissec...
Kazuhiro Shimizu,Ruiko Ohno,Masahiro Iwakawa et al.
Kazuhiro Shimizu et al.
Left ventricular hypertrophy (LVH), with the accompanying decrease in diastolic function, can originate from an augmented cardiac load caused by arterial stiffness (AS). The Cardio-Ankle Vascular Index (CAVI) is widely used as a good evalua...
Observational Study
International heart journal. 2025;66(3):449-455. DOI:10.1536/ihj.24-727 2025
High Prevalence of Thyroid Gland Dysfunction after Pulmonary Arterial Hypertension Treatment According to Real-World Data [0.03%]
基于真实世界数据的肺动脉高压治疗后甲状腺功能障碍的高发率
Noriaki Takama,Yohei Ishibashi,Batgerel Naidankhoo et al.
Noriaki Takama et al.
Continuous intravenous epoprostenol or treprostinil therapy is essential for the treatment of severe pulmonary arterial hypertension (PAH). However, it has several side effects, including thyroid gland dysfunction. This study aimed to estim...
Association Between Hemodynamic Monitoring Need and Prognosis of Patients with Sepsis in the Intensive Care Unit [0.03%]
重症监护室脓毒症患者血流动力学监测需求及其预后之间的关系研究
Ruitong Zhou,Le Fu,Yide Li et al.
Ruitong Zhou et al.
Sepsis, a life-threatening disease characterized by organ dysfunction, is primarily caused by an abnormally regulated host response to infection. This study aimed to evaluate the association between hemodynamic monitoring (HM) and the progn...
Relationship between Uric Acid and All-Cause and Cardiovascular Mortality in Individuals with Hypertension [0.03%]
高血压患者尿酸与全因及心血管死亡关系的前瞻性队列研究
Tian-Ming Gan,Yingjie Yang,Guan-Lian Mo et al.
Tian-Ming Gan et al.
Hypertension is a common disease in the general population. Serum uric acid (SUA) levels have been linked to the occurrence and worsening of hypertension. However, it is unclear whether SUA has an impact on all-cause mortality (ACM) and car...