Biomedical advances and future prospects of high-precision three-dimensional radiotherapy and four-dimensional radiotherapy [0.03%]
高精度三维和四维放疗的医学进展与未来展望
Hiroki Shirato
Hiroki Shirato
Biomedical advances of external-beam radiotherapy (EBRT) with improvements in physical accuracy are reviewed. High-precision (±1 mm) three-dimensional radiotherapy (3DRT) can utilize respective therapeutic open doors in the tumor control p...
Sooyeon Kim,Latiefa Kamarulzaman,Yuichi Taniguchi
Sooyeon Kim
Studying the central dogma at the single-cell level has gained increasing attention to reveal hidden cell lineages and functions that cannot be studied using traditional bulk analyses. Nonetheless, most single-cell studies exploiting genomi...
Highly enantioselective hydroxymethylation of unmodified α-substituted aryl ketones in water [0.03%]
未修饰的α-取代芳香酮在水中的高对映选择性羟甲基化反应
Taku Kitanosono,Tomoya Kawase,Yasuhiro Yamashita et al.
Taku Kitanosono et al.
Catalytic asymmetric direct-type aldol reactions of ketones with aldehydes are a perennial puzzle for organic chemists. Notwithstanding the emergence of a myriad of chiral catalysts to address the inherent reversibility of the aldol product...
On the occasion of the 100th volume of the Proceedings of the Japan Academy, Series B (PJA-B) [0.03%]
纪念日本学术会议Bulletin(B辑)刊行第100卷
Kunihiko Suzuki,Shigekazu Nagata
Kunihiko Suzuki
Hiroyuki Isobe,Masahiro Hirama
Hiroyuki Isobe
Rikō Majima published seven papers in this journal, and seeing these papers and their surrounding contexts allows us to glance at the birth of a galaxy of scientists. ...
At the dawn of novel aromatics: "On the Synthesis of Hinokitiol" by Tetsuo Nozoe et al [0.03%]
新颖芳香族化合物的黎明——端田哲夫等《关于桧醇的合成》论文
Hiroyuki Isobe
Hiroyuki Isobe
A paper titled "On the Synthesis of Hinokitiol" appeared in this journal in 1950 and marked the beginning of a new research field of novel aromatics. ...
Shigekazu Nagata
Shigekazu Nagata
In the late 1970s, crude interferon samples were found to exhibit anti-tumour activity. This discovery led to the interferon as a "magic drug" for cancer patients. Many groups, including those in Tokyo, Zürich, and San Francisco, attempted...
Improvement of patient care using cancer genomic profiling: SCRUM-/CIRCULATE-Japan experience [0.03%]
基于癌症基因组谱分析的患者治疗改善：SCRUM-/CIRCULATE-日本经验
Atsushi Ohtsu,Koichi Goto,Takayuki Yoshino
Atsushi Ohtsu
We launched SCRUM-Japan platform for the cancer genome profiling (CGP) test screening followed by the enrollment to genomically-matched clinical trials in 2015. More than 30,000 tissue-based and 10,000 liquid-based CGP tests have already be...
Thirty-five years since the discovery of chemotactic cytokines, interleukin-8 and MCAF: A historical overview [0.03%]
趋化性细胞因子的发现——白细胞介素-8和MCAF三十年回顾
Kouji Matsushima,Shigeyuki Shichino,Satoshi Ueha
Kouji Matsushima
Inflammation is a host defense response to various invading stimuli, but an excessive and persistent inflammatory response can cause tissue injury, which can lead to irreversible organ damage and dysfunction. Excessive inflammatory response...
Environmental catalysts advance focused on lattice oxygen for the decomposition of harmful organic compounds [0.03%]
环境催化剂研究聚焦晶格氧在有害有机物分解中的作用
Nobuhito Imanaka,Naoyoshi Nunotani
Nobuhito Imanaka
The recent industrial growth has made our lives more comfortable; however, it has led to an increase in the concentration of harmful compounds, such as carbon monoxide, volatile organic compounds (e.g., toluene), and phenolic compounds (e.g...