Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms [0.03%]
土壤微生物产生的两类几丁质抑制剂Argifin和Argadin的研究进展
Tomoyasu Hirose,Toshiaki Sunazuka,Satoshi Omura
Tomoyasu Hirose
Chitin, the second most abundant polysaccharide in nature, occurs in fungi, some algae and many invertebrates, including insects. Thus, chitin synthesis and degradation could represent specific targets for fungicides and insecticides. Chiti...
Inside view of cell locomotion through single-molecule: fast F-/G-actin cycle and G-actin regulation of polymer restoration [0.03%]
单分子视角下的细胞运动：快速F-/G-肌动蛋白循环和单体肌动蛋白调控聚合物重建
Naoki Watanabe
Naoki Watanabe
The actin cytoskeleton drives cell locomotion and tissue remodeling. The invention of live-cell fluorescence single-molecule imaging opened a window for direct viewing of the actin remodeling processes in the cell. Since then, a number of u...
Kazutomo Imahori
Kazutomo Imahori
Alzheimer's disease has been characterized by senile plaque and neurofibrillary tangle in the brain. However, their relation to etiology of this disease has been left unclear. Recently it has been clarified that neurofibrillary tangle consi...
Molecular mechanisms of the physiological functions of the aryl hydrocarbon (dioxin) receptor, a multifunctional regulator that senses and responds to environmental stimuli [0.03%]
芳烃受体（二恶英受体）的生理功能及其分子机制，一种能感应和应答环境刺激的多功能调节因子
Yoshiaki Fujii-Kuriyama,Kaname Kawajiri
Yoshiaki Fujii-Kuriyama
The aryl hydrocarbon receptor (AhR) was originally identified as a ligand-activated transcription factor that is involved in the induction of xenobiotic-metabolizing Cytochrome P4501A1 (CYP1A1). For several decades, AhR has been studied in ...
Unique features of animal mitochondrial translation systems. The non-universal genetic code, unusual features of the translational apparatus and their relevance to human mitochondrial diseases [0.03%]
动物线粒体翻译系统的独特特征。非通用遗传密码、翻译装置的特殊性质及其与人类线粒体疾病的相关性
Kimitsuna Watanabe
Kimitsuna Watanabe
In animal mitochondria, several codons are non-universal and their meanings differ depending on the species. In addition, the tRNA structures that decipher codons are sometimes unusually truncated. These features seem to be related to the s...
Spectroscopy of antiprotonic helium atoms and its contribution to the fundamental physical constants [0.03%]
反质子氦原子光谱及其对基本物理常数的贡献
Ryugo S Hayano
Ryugo S Hayano
Antiprotonic helium atom, a metastable neutral system consisting of an antiproton, an electron and a helium nucleus, was serendipitously discovered, and has been studied at CERN's antiproton decelerator facility. Its transition frequencies ...
Mechanism of cadmium induced crystal defects in developing rat tooth enamel [0.03%]
镉致大鼠乳牙釉质发育缺陷的机理研究
Mitsuo Kakei,Toshiro Sakae,Masayoshi Yoshikawa
Mitsuo Kakei
It is well known that exposure to environmental cadmium causes itai-itai (ouch-ouch) disease. However, the exact mechanism underlying this bone disease remains unresolved. By focusing on the calcification mechanism, we examined developing t...
Atsuko H Iwane,Masatoshi Morimatsu,Toshio Yanagida
Atsuko H Iwane
Until recently, actin was thought to act merely as a passive track for its motility partner, myosin, during actomyosin interactions. Yet a recent report having observed dynamical conformational changes in labeled skeletal muscle alpha-actin...
Development of newly designed VHF interferometer system for observing earthquake-related atmospheric anomalies [0.03%]
一种观测与地震相关的大气异常的新设计的VHF干涉仪系统的发展
Isao Yamamoto,Hironobu Fujiwara,Masashi Kamogawa et al.
Isao Yamamoto et al.
Temporal correlation between atmospheric anomalies and earthquakes has recently been verified statistically through measuring VHF FM radio waves transmitted beyond the line-of-sight. In order to locate the sources of such atmospheric anomal...
Yoshiaki Orihara,Masashi Kamogawa,Toshiyasu Nagao et al.
Yoshiaki Orihara et al.
Nearly twenty anomalous geoelectric field changes were observed before earthquakes at Kozu-shima Island, Japan, from 1997 to 2000. In order to help locating the current sources of the observed anomalous changes, a bipole-dipole resistivity ...