Teruo Ono,Shoji Odani
Teruo Ono
Our colleagues and we have determined the complete primary structure of a low molecular weight cytoplasmic FABP (also known as z-protein) that binds to LCFAs with high affinities, obtained from rat liver. At the same time, we were the first...
Asymmetric hydrogenation of ketones: tactics to achieve high reactivity, enantioselectivity, and wide scope [0.03%]
酮的不对称氢化：实现高活性、对映选择性和广泛底物范围的方法学研究
Takeshi Ohkuma
Takeshi Ohkuma
Ru complexes with chiral diphosphines and amine-based ligands achieve high catalytic activity and enantioselectivity for the hydrogenation of ketones under neutral to slightly basic conditions. The chiral environment is controllable by chan...
Exploratory research on bioactive natural products with a focus on biological phenomena [0.03%]
以生命现象为导向的活性天然产物探索研究
Daisuke Uemura
Daisuke Uemura
The discovery of new basic compounds holds the key for advancing material sciences. We have focused on the identification and characterization of natural key compounds that control biologically and physiologically intriguing phenomena. The ...
Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity [0.03%]
两种日本海兔的细胞毒活性物质：化学及生物活性研究
Kiyoyuki Yamada,Makoto Ojika,Hideo Kigoshi et al.
Kiyoyuki Yamada et al.
From the sea hares belonging to two genera, Aplysia and Dolabella, a variety of new cytotoxic substances were isolated as minute constituents: their chemical structures were determined and their cytotoxicity was evaluated. Regarding the hig...
Polyamorphism in water [0.03%]
水的多胺聚形态
Osamu Mishima
Osamu Mishima
Water, the most common and important liquid, has peculiar properties like the density maximum at 4 degrees C. Such properties are thought to stem from complex changes in the bonding-network structure of water molecules. And yet we cannot un...
Hironari Miyazawa
Hironari Miyazawa
Fermions and bosons are quite different kinds of particles, but it is possible to unify them in a supermultiplet, by introducing a new mathematical scheme called superalgebra. In this article we discuss the development of the concept of sym...
Toshiki Tajima
Toshiki Tajima
Laser acceleration is based on the concept to marshal collective fields that may be induced by laser. In order to exceed the material breakdown field by a large factor, we employ the broken-down matter of plasma. While the generated wakefie...
Establishment of a concept of visceral fat syndrome and discovery of adiponectin [0.03%]
内脏脂肪症候群的概念建立及脂连素的发现
Yuji Matsuzawa
Yuji Matsuzawa
Although obesity is a major background of life style-related diseases such as diabetes mellitus, lipid disorder, hypertension and cardiovascular disease, the extent of whole body fat accumulation does not necessarily the determinant for the...
Molecular approach to human leukemia: isolation and characterization of the first human retrovirus HTLV-1 and its impact on tumorigenesis in adult T-cell leukemia [0.03%]
人类白血病的分子方法：HTLV-1的人类第一个逆转录病毒的分离、表征及其对成人T细胞白血病发病机制的影响
Mitsuaki Yoshida
Mitsuaki Yoshida
Molecular biology of mouse and chicken retroviruses had identified oncogenes and provided a revolutionary concept in understanding of cancers. A human retrovirus was established during 1980-1982 in linkage with a unique human leukemia, conc...
Recent advances in rice genome and chromosome structure research by fluorescence in situ hybridization (FISH) [0.03%]
近年应用荧光原位杂交技术研究水稻基因组与染色体结构的进展
Nobuko Ohmido,Kiichi Fukui,Toshiro Kinoshita
Nobuko Ohmido
Fluorescence in situ hybridization (FISH) is an effective method for the physical mapping of genes and repetitive DNA sequences on chromosomes. Physical mapping of unique nucleotide sequences on specific rice chromosome regions was performe...