Yoshibumi Tomoda
Yoshibumi Tomoda
A history of studies on the gravity measurements at sea in Japan is reviewed with an emphasis on the contribution of the author. The first successful measurements at sea were made in 1923 by Vening Meinesz in the Netherlands using the pendu...
Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica [0.03%]
药用植物黄连中异喹啉类生物碱O-甲基转移酶的分子特性研究
Takashi Morishige,Masanori Tamakoshi,Tomoya Takemura et al.
Takashi Morishige et al.
O-Methyltransferases, which catalyze the production of small molecules in plants, play a crucial role in determining biosynthetic pathways in secondary metabolism because of their strict substrate specificity. Using three O-methyltransferas...
Progress in muscular dystrophy research with special emphasis on gene therapy [0.03%]
肌营养不良症研究进展——特别关注基因治疗
Hideo Sugita,Shin&#x;ichi Takeda
Hideo Sugita
Duchenne muscular dystrophy (DMD) is an X-linked, progressive muscle-wasting disease caused by mutations in the DMD gene. Since the disease was described by physicians in the 19th century, information about the subject has been accumulated....
Akira Kobata
Akira Kobata
Comparative study of the oligosaccharide profiles of individual human milk revealed the presence of three different patterns. Four oligosaccharides containing the Fucalpha1-2Gal group were missing in the milk of non-secretor, and three olig...
Interleukin 6 in autoimmune and inflammatory diseases: a personal memoir [0.03%]
自身免疫和炎症性疾病中的白细胞介素 6：个人回忆
Toshio Hirano
Toshio Hirano
In this review, the author discusses the research that led to the identification and characterization of interleukin 6 (IL-6), including his own experience isolating IL-6, and the roles this cytokine has on autoimmune and inflammatory disea...
Akira Ichihara
Akira Ichihara
This article summarizes my research over 40 years. The main theme of my work is nitrogen metabolism of amino acids, though later I focused on protein turnover in the cell. In the first years of my research work, I was busy dissecting the pa...
Transthyretin-related familial amyloidotic polyneuropathy-Progress in Kumamoto, Japan (1967-2010)- [0.03%]
甲状腺素转运蛋白相关的家族性淀粉样变性多发神经病变——日本熊本（1967-2010）的进展
Shukuro Araki,Yukio Ando
Shukuro Araki
The authors reviewed contribution of Kumamoto University group to the progress of the studies on transthyretin (TTR)-related familial amyloidotic polyneuropathy (TTR-related FAP) for 42 years (from 1967 to 2009). Andrade (1952) first descri...
Yasuo Kagawa
Yasuo Kagawa
ATP synthase (F(o)F(1)) consists of an ATP-driven motor (F(1)) and a H(+)-driven motor (F(o)), which rotate in opposite directions. F(o)F(1) reconstituted into a lipid membrane is capable of ATP synthesis driven by H(+) flux. As the basic s...
Seiji Miyashita
Seiji Miyashita
Various types ordering processes in systems with large fluctuation are overviewed. Generally, the so-called order-disorder phase transition takes place in competition between the interaction causing the system be ordered and the entropy cau...
Conversion of brain cytosol profile from fetal to adult type during the perinatal period: taurine-NAA exchange [0.03%]
围生期脑细胞溶质从胎儿型向成人型转换：taurom宁酰胺的交换
Tsutomu Nakada
Tsutomu Nakada
Mammals face drastic environmental changes at birth. Appropriate adjustments of various systems must take place rapidly to accommodate this once in a life time event. The brain undergoes significant adjustments as well, the most obvious of ...