Thrombocytogenesis by megakaryocyte; Interpretation by protoplatelet hypothesis [0.03%]
巨核细胞血小板生成的原小板假说解释
Goro Kosaki,Junichi Kambayashi
Goro Kosaki
Serial transmission electron microscopy of human megakaryocytes (MKs) revealed their polyploidization and gradual maturation through consecutive transition in characteristics of various organelles and others. At the beginning of differentia...
Development of biomimetic catalytic oxidation methods and non-salt methods using transition metal-based acid and base ambiphilic catalysts [0.03%]
基于过渡金属的酸碱双功能催化剂仿生催化氧化及非盐方法的发展研究
Shun-Ichi Murahashi
Shun-Ichi Murahashi
This review focuses on the development of ruthenium and flavin catalysts for environmentally benign oxidation reactions based on mimicking the functions of cytochrome P-450 and flavoenzymes, and low valent transition-metal catalysts that re...
Transition metal catalyzed manipulation of non-polar carbon-hydrogen bonds for synthetic purpose [0.03%]
过渡金属催化的非极性碳氢键的合成转化
Shinji Murai
Shinji Murai
The direct addition of ortho C-H bonds in various aromatic compounds such as ketones, esters, imines, imidates, nitriles, and aldehydes to olefins and acetylenes can be achieved with the aid of transition metal catalysts. The ruthenium cata...
Masayuki Nakahata
Masayuki Nakahata
Solar neutrino experiments observed fluxes smaller than the expectations from the standard solar model. This discrepancy is known as the "solar neutrino problem". Flux measurements by Super-Kamiokande and SNO have demonstrated that the sola...
2-Aminophenoxazine-3-one and 2-amino-4,4α-dihydro-4α,7-dimethyl-3H-phenoxazine-3-one cause cellular apoptosis by reducing higher intracellular pH in cancer cells [0.03%]
2-氨基苯氧azines-3-酮和2-氨基-4,4α-二氢-4α,7-二甲基-3H-苯氧嗪-3-酮通过降低癌细胞内的pH值诱导细胞凋亡
Xiao-Fang Che,Chun-Lei Zheng,Shin-Ichi Akiyama et al.
Xiao-Fang Che et al.
We examined intracellular pH (pHi) of ten cancer cell lines derived from different organs and two normal cell lines including human embryonic lung fibroblast cells (HEL) and human umbilical vein endothelial cells (HUVEC) in vitro, and found...
Jin-ichi Inokuchi
Jin-ichi Inokuchi
Since I was involved in the molecular cloning of GM3 synthase (SAT-I), which is the primary enzyme for the biosynthesis of gangliosides in 1998, my research group has been concentrating on our efforts to explore the physiological and pathol...
Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia [0.03%]
Flt-1（血管内皮生长因子受体-1）与癌症和子痫前期的关系
Masabumi Shibuya
Masabumi Shibuya
We previously isolated a novel tyrosine kinase receptor, Flt-1, now known as VEGF-receptor (VEGFR)-1. The VEGF-VEGFR system plays a pivotal role in not only physiological but also pathological angiogenesis. We examined the role of Flt-1 in ...
Establishment of the milk-borne transmission as a key factor for the peculiar endemicity of human T-lymphotropic virus type 1 (HTLV-1): the ATL Prevention Program Nagasaki [0.03%]
母乳传播是成人T细胞白血病病毒Ⅰ型(HTLV-1)特异流行的关键因素：长崎预防计划
Shigeo Hino
Shigeo Hino
In late 2010, the nation-wide screening of pregnant women for human T-lymphotropic virus type 1 (HTLV-1) infection was implemented in Japan to prevent milk-borne transmission of HTLV-1. In the late 1970s, recognition of the adult T-cell leu...
Computational performance of Free Mesh Method applied to continuum mechanics problems [0.03%]
自由网格法在连续介质力学问题中的计算性能分析
Genki Yagawa
Genki Yagawa
The free mesh method (FMM) is a kind of the meshless methods intended for particle-like finite element analysis of problems that are difficult to handle using global mesh generation, or a node-based finite element method that employs a loca...
Genki Yagawa
Genki Yagawa
The finite element method (FEM) has been commonly employed in a variety of fields as a computer simulation method to solve such problems as solid, fluid, electro-magnetic phenomena and so on. However, creation of a quality mesh for the prob...