Konrad Sandhoff
Konrad Sandhoff
Analysis of lipid storage in postmortem brains of patients with amaurotic idiocy led to the recognition of five lysosomal ganglioside storage diseases and identification of their inherited metabolic blocks. Purification of lysosomal acid sp...
Reminiscence of our research on membrane phospholipids in mammalian cells by using the novel technology [0.03%]
回忆我们应用新技术进行哺乳类细胞膜磷酸脂研究的日子
Yuzuru Akamatsu
Yuzuru Akamatsu
By using "our devised up-to-the-second technique" over 30 years ago, we succeeded in the first isolation in the world of the three different kinds of mammalian cell mutants defective in the biosynthesis on each of phosphatidylserine (PS), c...
Molecular genetics, physiology and biology of self-incompatibility in Brassicaceae [0.03%]
十字花科自交不亲和性的分子遗传、生理及其生物学机制研究进展
Masao Watanabe,Keita Suwabe,Go Suzuki
Masao Watanabe
Self-incompatibility (SI) is defined as the inability to produce zygotes after self-pollination in a fertile hermaphrodite plant, which has stamens and pistils in the same flower. This structural organization of the hermaphrodite flower inc...
A group of glycosphingolipids found in an invertebrate: their structures and biological significance [0.03%]
无脊椎动物糖脂的多样性：结构与生物学意义
Mei Satake,Eishichi Miyamoto
Mei Satake
A novel group of glycosphingolipids was identified in the nervous tissue and skin of the mollusc, Aplysia kurodai, which lacks gangliosides. More than 30 glycolipids were detected on HPTLC plates and the structures of 9 major glycolipids we...
Akira Ishihama
Akira Ishihama
After determination of the whole genome sequence, the research frontier of bacterial molecular genetics has shifted to reveal the genome regulation under stressful conditions in nature. The gene selectivity of RNA polymerase is modulated af...
Accident at the Fukushima Dai-ichi nuclear power stations of TEPCO--outline & lessons learned [0.03%]
福岛第一核电厂事故概要及教训
Shun-ichi Tanaka
Shun-ichi Tanaka
The severe accident that broke out at Fukushima Dai-ichi nuclear power stations on March 11, 2011, caused seemingly infinite damage to the daily life of residents. Serious and wide-spread contamination of the environment occurred due to rad...
Happy experience of a medical doctor curing from pancreatic cancer: a 60-day diary [0.03%]
一名医生的抗癌经历——胰腺癌患者60天日记
Yousuke Seyama
Yousuke Seyama
Pancreatic cancer was found by an abdominal CT scan in a medical doctor, the author of this article, before the appearance of any symptoms. After considering all the imaging findings including the CT, MRI, and PET, a diagnosis was made. He ...
Intra-abdominal fat area is a predictor for new onset of individual components of metabolic syndrome: MEtabolic syndRome and abdominaL ObesiTy (MERLOT study) [0.03%]
腹腔内脂肪面积是代谢综合征各组分新发事件的预测因子：MEtabolic syndRome and abdominaL ObesiTy（MERLOT研究）
Yoko M Nakao,Takashi Miyawaki,Shinji Yasuno et al.
Yoko M Nakao et al.
Objective: To investigate the significance of intra-abdominal fat area (IAFA) on new onset of individual components of the metabolic syndrome: high blood pressure, dyslipidemia, or hyperglycemia. ...
Ryoichi Hayakawa,Teruyuki Hayakawa,Kohsuke Takeda et al.
Ryoichi Hayakawa et al.
Apoptosis signal-regulating kinase 1 (ASK1) is a member of the mitogen-activated protein kinase kinase kinase (MAP3K) family that activates downstream MAP kinases (MAPKs), c-Jun N-terminal kinases (JNKs) and p38 MAPKs, in response to variou...
Hideaki Tanaka,Tomitake Tsukihara
Hideaki Tanaka
Vault is the largest nonicosahedral cytosolic nucleoprotein particle ever described. The widespread presence and evolutionary conservation of vaults suggest important biologic roles, although their functions have not been fully elucidated. ...