Jiro Suzuki
Jiro Suzuki
The convulsions of the EL mouse (EL) were described by Imaizumi et al. in 1954 and were established as epilepsy by Suzuki in 1976. The EL mouse has been kept as an inbred strain and is considered one of the best animal models originated in ...
Donald M Marcus
Donald M Marcus
The research program of my laboratory included three major topics: the structures and immunology of human carbohydrate blood group and glycosphingolipid antigens; the tissue distribution, subcellular localization and biosynthesis of glycosp...
Tatsuya Haga
Tatsuya Haga
Muscarinic acetylcholine receptors, which comprise five subtypes (M1-M5 receptors), are expressed in both the CNS and PNS (particularly the target organs of parasympathetic neurons). M1-M5 receptors are integral membrane proteins with seven...
Structure and function studies on enzymes with a catalytic carboxyl group(s): from ribonuclease T1 to carboxyl peptidases [0.03%]
催化羧基酶的结构与功能研究：从核糖核酸酶T1到羧基肽酶
Kenji Takahashi
Kenji Takahashi
A group of enzymes, mostly hydrolases or certain transferases, utilize one or a few side-chain carboxyl groups of Asp and/or Glu as part of the catalytic machinery at their active sites. This review follows mainly the trail of studies perfo...
Estimation of the total population moving into and out of the 20 km evacuation zone during the Fukushima NPP accident as calculated using "Auto-GPS" mobile phone data [0.03%]
利用手机GPS数据估算福岛事故期间20公里疏散区内的总人口流动量
Ryugo S Hayano,Ryutaro Adachi
Ryugo S Hayano
The first objective data showing the geographical locations of people in Fukushima after the Fukushima Dai-ichi nuclear power plant accident, obtained by an analysis of GPS (Global Positioning System)-enabled mobile phone logs, are presente...
Tomoo Hirano
Tomoo Hirano
Cerebellar long-term depression (LTD) is a type of synaptic plasticity and has been considered as a critical cellular mechanism for motor learning. LTD occurs at excitatory synapses between parallel fibers and a Purkinje cell in the cerebel...
Microbial production of isoquinoline alkaloids as plant secondary metabolites based on metabolic engineering research [0.03%]
基于代谢工程研究的异喹啉类生物碱微生物合成体系构建及优化
Fumihiko Sato,Hidehiko Kumagai
Fumihiko Sato
Plants produce a variety of secondary metabolites that possess strong physiological activities. Unfortunately, however, their production can suffer from a variety of serious problems, including low levels of productivity and heterogeneous q...
Internal radiocesium contamination of adults and children in Fukushima 7 to 20 months after the Fukushima NPP accident as measured by extensive whole-body-counter surveys [0.03%]
福岛核事故后7至20个月大人和小孩体内放射性铯污染的分布：全身计数器调查结果
Ryugo S Hayano,Masaharu Tsubokura,Makoto Miyazaki et al.
Ryugo S Hayano et al.
The Fukushima Dai-ichi NPP accident contaminated the soil of densely-populated regions in Fukushima Prefecture with radioactive cesium, which poses significant risks of internal and external exposure to the residents. If we apply the knowle...
Synaptic inhibition and γ-aminobutyric acid in the mammalian central nervous system [0.03%]
哺乳动物中枢神经系统的突触抑制和γ氨基丁酸
Kunihiko Obata
Kunihiko Obata
Signal transmission through synapses connecting two neurons is mediated by release of neurotransmitter from the presynaptic axon terminals and activation of its receptor at the postsynaptic neurons. γ-Aminobutyric acid (GABA), non-protein ...
Koichi Honke
Koichi Honke
Sulfation confers negative charge on glycolipids and the attached sulfate group presents a part of determinants for the molecular interactions. Mammalian sulfoglycolipids are comprised of two major members, sulfatide (SO3-3Gal-ceramide) and...